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  1. Content type: Protocol

    Parents of babies admitted to neonatal units experience an arduous emotional journey. Feelings of helplessness, fear, sadness, guilt, grief and anger are common. These feelings can lead to anxiety, depression ...

    Authors: Harriet Hunt, Rebecca Whear, Kate Boddy, Leanna Wakely, Alison Bethel, Christopher Morris, Rebecca Abbott, Susan Prosser, Andrew Collinson, Jennifer Kurinczuk and Jo Thompson-Coon

    Citation: Systematic Reviews 2018 7:179

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  2. Content type: Protocol

    Liver transplant recipients suffer many complications, but few intraoperative interventions supported by high-quality evidence have been found effective to reduce their incidence or severity. Fluid balance has...

    Authors: François Martin Carrier, Michaël Chassé, Han Ting Wang, Pierre Aslanian, Marc Bilodeau and Alexis F. Turgeon

    Citation: Systematic Reviews 2018 7:180

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  3. Content type: Protocol

    Data on the effects of motivational interviewing (MI) on modifying unhealthy lifestyles and promoting weight status during childhood is controversial. Adolescents are more prone to assume higher personal respo...

    Authors: Parisa Amiri, Elham Kazemian, Mohammad Masih Mansouri-Tehrani, Ahmad Khalili and Atieh Amouzegar

    Citation: Systematic Reviews 2018 7:178

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  4. Content type: Protocol

    Chronic diseases contribute to about half of the adult disease burden in the South Asian region. Meanwhile, physical activity levels are declining despite the global evidence of its role in the prevention of c...

    Authors: Susan Paudel, Alice J. Owen, Ebenezer Owusu-Addo and Ben J. Smith

    Citation: Systematic Reviews 2018 7:177

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  5. Content type: Research

    Outcome after nerve repair of the hand needs standardized psychometrically robust measures. We aimed to systematically review the psychometric properties of available functional, motor, and sensory assessment ...

    Authors: Marisa de Cássia Registro Fonseca, Valéria Meireles Carril Elui, Emily Lalone, Natália Claro da Silva, Rafael Inácio Barbosa, Alexandre Márcio Marcolino, Flávia Pessoni Faleiros Macedo Ricci and Joy C. MacDermid

    Citation: Systematic Reviews 2018 7:175

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  7. Content type: Protocol

    People with mobility impairments may have difficulties in everyday life motor activities, and assessing these difficulties is crucial to plan rehabilitation interventions and evaluate their effectiveness. Wear...

    Authors: Fabian Marcel Rast and Rob Labruyère

    Citation: Systematic Reviews 2018 7:174

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  8. Content type: Research

    Systematic reviews (SRs) depend on comprehensive searches for evidence to provide balanced, accurate results. Requesting published and unpublished studies from pharmaceutical manufacturers has been proposed as...

    Authors: Marian S. McDonagh, Sujata Thakurta and Kim Peterson

    Citation: Systematic Reviews 2018 7:172

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  9. Content type: Protocol

    Respiratory failure requiring mechanical ventilation is a common manifestation of end-organ damage among patients with sepsis and has a high morbidity and mortality rate, as well as substantial associated trea...

    Authors: Thomas P. Clyde, Michael Coletta, Christopher Jones, Hope Kilgannon, Brian M. Fuller, Stephen Trzeciak and Brian W. Roberts

    Citation: Systematic Reviews 2018 7:171

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  10. Content type: Protocol

    Acute kidney injury (AKI) refers to a broad spectrum of kidney damage and is attributed a high morbidity and mortality rate at all degrees of severity. Obesity increases the risk for developing AKI. However, s...

    Authors: Maria P Barrett, David Moore, Fang Gao Smith and Indranil Dasgupta

    Citation: Systematic Reviews 2018 7:173

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  11. Content type: Research

    Conducting systematic reviews is time-consuming but crucial to construct evidence-based patient decision aids, clinical practice guidelines and decision analyses. New methods might enable developers to produce...

    Authors: Øystein Eiring, Kjetil Gundro Brurberg, Kari Nytrøen and Magne Nylenna

    Citation: Systematic Reviews 2018 7:168

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  12. Content type: Protocol

    Acute critical bleeding is one of the most feared complications during treatment with oral anticoagulating agents. As more patients undergo treatment with anticoagulating agents, critically bleeding episodes i...

    Authors: Christian Ovesen, Jan Purrucker, Christian Gluud, Janus Christian Jakobsen, Hanne Christensen and Thorsten Steiner

    Citation: Systematic Reviews 2018 7:169

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  13. Content type: Protocol

    The burden of non-communicable diseases such as type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVDs) has drastically increased in developing countries over the years. Although recent evidence poi...

    Authors: Tawanda M. Nyambuya, Phiwayinkosi V. Dludla and Bongani B. Nkambule

    Citation: Systematic Reviews 2018 7:167

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  14. Content type: Research

    Postpartum hemorrhage (PPH) and the amount of blood loss are directly related to management of the third stage of labor. No previous report has compared the effects of carbetocin to those of misoprostol. The a...

    Authors: Mohamed A. Abd El Aziz, Ahmed Iraqi, Parvin Abedi and Shayesteh Jahanfar

    Citation: Systematic Reviews 2018 7:170

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  15. Content type: Protocol

    Systematic information retrieval generally requires a two-step selection process for studies, which is conducted by two persons independently of one another (double-screening approach). To increase efficiency,...

    Authors: Siw Waffenschmidt, Elke Hausner, Wiebke Sieben, Thomas Jaschinski, Marco Knelangen and Inga Overesch

    Citation: Systematic Reviews 2018 7:166

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  16. Content type: Protocol

    Ethnic minorities in multi-ethnic societies like the UK and USA have poorer outcomes for some cancer types when compared with the majority. The causes of ethnic inequalities in cancer outcomes are complex and ...

    Authors: Bogdan Chiva Giurca, William Hamilton and Tanimola Martins

    Citation: Systematic Reviews 2018 7:164

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  17. Content type: Protocol

    Dyslipidemia is a major risk factor in triggering cardiovascular events, which can lead to the death of millions of people around the world. Thus, several pharmacological and non-pharmacological therapeutic st...

    Authors: Patricia M. Fortes, Solomar M. Marques, Karolline A. Viana, Luciane R. Costa, Alessandra V. Naghettini and Paulo Sucasas Costa

    Citation: Systematic Reviews 2018 7:165

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  19. Content type: Research

    Diabetes mellitus (DM) poses a significant risk for the development of active tuberculosis (TB) and complicates its treatment. However, there is inconclusive evidence on whether the TB-DM co-morbidity is assoc...

    Authors: Balewgizie Sileshi Tegegne, Melkamu Merid Mengesha, Andreas A. Teferra, Mamaru Ayenew Awoke and Tesfa Dejenie Habtewold

    Citation: Systematic Reviews 2018 7:161

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  20. Content type: Protocol

    Osteoarthritis is a degenerative joint disease that is highly prevalent worldwide. Knee osteoarthritis is the most common form of osteoarthritis and is a major cause of pain and disability. However, there rema...

    Authors: En Lin Goh, Winston Choong Ngan Lou, Swathikan Chidambaram and Shaocheng Ma

    Citation: Systematic Reviews 2018 7:162

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  21. Content type: Research

    Attentional bias modification (ABM) interventions have been developed to address addiction by reducing attentional bias for substance-related cues. This study provides a systematic review of the effectiveness ...

    Authors: Janika Heitmann, Elise C. Bennik, Madelon E. van Hemel-Ruiter and Peter J. de Jong

    Citation: Systematic Reviews 2018 7:160

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  22. Content type: Methodology

    Overviews of systematic reviews (SRs) attempt to systematically retrieve and summarise the results of multiple systematic reviews. This is the second of two papers from a study aiming to develop a comprehensiv...

    Authors: Carole Lunny, Sue E. Brennan, Steve McDonald and Joanne E. McKenzie

    Citation: Systematic Reviews 2018 7:159

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  23. Content type: Protocol

    According to the United Nations Trends in Contraceptive Use 2015 report, at least one in ten married or in-union women in most regions of the world has an unmet need for family planning. Family Planning 2020 r...

    Authors: Shimona Prosad, Tivani P Mashamba-Thompson and Elizabeth Ojewole

    Citation: Systematic Reviews 2018 7:157

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  24. Content type: Protocol

    Magnetic resonance spectroscopy (MRS) is a non-invasive analytical technique that investigates the presence and concentrations of brain metabolites. In the context of major depressive disorder (MDD), MRS has r...

    Authors: Thomas Drago, Patrick W O’Regan, Ivan Welaratne, Shane Rooney, Aoife O’Callaghan, Marissa Malkit, Elena Roman, Kirk J Levins, Lauren Alexander, Denis Barry, Erik O’Hanlon, Veronica O’Keane and Darren William Roddy

    Citation: Systematic Reviews 2018 7:158

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  25. Content type: Research

    Postpartum haemorrhage is a direct cause of maternal death worldwide and usually occurs during the third stage of labour. Most women receive some type of prophylactic management, which may include pharmacologi...

    Authors: Yuko Masuzawa, Yaeko Kataoka, Kana Fujii and Satomi Inoue

    Citation: Systematic Reviews 2018 7:156

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  27. Content type: Protocol

    By 2035, older adults will outnumber children for the first time in the United States (US). In light of its aging population, the US has supported services focused on enabling older adults to continue living i...

    Authors: Amy Rosenwohl-Mack, Karen Schumacher, Min-Lin Fang and Yoshimi Fukuoka

    Citation: Systematic Reviews 2018 7:155

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  28. Content type: Research

    Comparisons between narrative synthesis and meta-analysis as synthesis methods in systematic reviews are uncommon within the same systematic review. We re-analysed a systematic review on the effects of plain p...

    Authors: G J Melendez-Torres, James Thomas, Theo Lorenc, Alison O’Mara-Eves and Mark Petticrew

    Citation: Systematic Reviews 2018 7:153

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  29. Content type: Protocol

    Surgical site infection describes an infectious complication of surgical wounds. This single complication is thought to occur in close to 20% of surgical cases. This complication has been described in all kind...

    Authors: Dawid Pieper, Tanja Rombey, Johannes Doerner, Julian-Dario Rembe, Hubert Zirngibl, Konstantinos Zarras and Peter C. Ambe

    Citation: Systematic Reviews 2018 7:152

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  30. Content type: Protocol

    Heart failure (HF) is a common condition affecting more than 10% of those over 70 years of age. Reliable estimates of survival following a diagnosis of HF are important to guide management and facilitate advan...

    Authors: Nicholas R. Jones, Andrea K. Roalfe, Ibiye Adoki, F. D. Richard Hobbs and Clare J. Taylor

    Citation: Systematic Reviews 2018 7:151

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  31. Content type: Protocol

    Acute coronary syndrome (ACS) is a common, sometimes difficult to diagnose spectrum of diseases occurring after abrupt reduction in blood flow through a coronary artery. Given the diagnostic challenge, it is s...

    Authors: Christopher Byrne, Cristian Toarta, Barbra Backus and Tim Holt

    Citation: Systematic Reviews 2018 7:148

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  33. Content type: Protocol

    Low back pain (LBP) is one of the most prevalent and recurrent conditions in the general population, with personal, professional, social and economic impact. However, there is a lack of consistent evidence abo...

    Authors: Liliane Mendonça, Matilde Monteiro-Soares and Luís Filipe Azevedo

    Citation: Systematic Reviews 2018 7:149

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  34. Content type: Protocol

    Hepatitis B causes death mainly due to liver disease worldwide. Human immunodeficiency virus increases the pathological effect of hepatitis viruses and potentiates re-activation of latent hepatitis infections ...

    Authors: Steve Leumi, Jean Joel Bigna, Marie A. Amougou, Leopold N. Aminde, Ulrich Flore Nyaga and Jean Jacques Noubiap

    Citation: Systematic Reviews 2018 7:146

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  36. Content type: Protocol

    Mendelian randomization (MR) is fast becoming a popular method to judge causality from routinely conducted observational studies. However, stringent underlying statistical assumptions, missing biological infor...

    Authors: Sandeep Grover, Fabiola Del Greco M. and Inke R. König

    Citation: Systematic Reviews 2018 7:145

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  37. Content type: Research

    Hypomethylating agents (HMA), azacitidine, and decitabine are frequently used in the management of myelodysplastic syndromes (MDS). However, there are no clinical trials that have directly compared these agent...

    Authors: Jehad Almasri, Hassan B. Alkhateeb, Belal Firwana, Mohamad Bassam Sonbol, Moussab Damlaj, Zhen Wang, M. Hassan Murad and Aref Al-Kali

    Citation: Systematic Reviews 2018 7:144

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  38. Content type: Protocol

    A key determinant of survival after out-of-hospital cardiac arrest (OHCA) is bystander cardio pulmonary resuscitation (CPR) which can more than double an individual’s chances of surviving to discharge from hos...

    Authors: Fiona Dobbie, Kathryn Angus, Isabelle Uny, Edward Duncan, Lisa MacInnes, Liz Hasseld and Gareth Clegg

    Citation: Systematic Reviews 2018 7:143

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  39. Content type: Protocol

    Failure to sustain knowledge translation (KT) interventions impacts patients and health systems, diminishing confidence in future implementation. Sustaining KT interventions used to implement chronic disease m...

    Authors: Andrea C. Tricco, Julia E. Moore, Nicole Beben, Ross C. Brownson, David A. Chambers, Lisa R. Dolovich, Annemarie Edwards, Lee Fairclough, Paul P. Glasziou, Ian D. Graham, Brenda R. Hemmelgarn, Bev Holmes, Wanrudee Isaranuwatchai, Chantelle C. Lachance, France Legare, Jessie McGowan…

    Citation: Systematic Reviews 2018 7:140

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  40. Content type: Protocol

    Suboptimal diagnostics for pulmonary tuberculosis (PTB) drives use of ‘trial-of-antibiotics (non-tuberculosis)’ in an attempt to distinguish PTB patients from those with bacterial lower respiratory tract infec...

    Authors: Titus H. Divala, Katherine L. Fielding, Marriott Nliwasa, Derek J. Sloan, Ankur Gupta-Wright and Elizabeth L. Corbett

    Citation: Systematic Reviews 2018 7:141

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  41. Content type: Research

    Estimates of survival for women diagnosed with early staged breast cancer are available based on stratification into prognostic categories defined using the Nottingham Prognostic Index (NPI). This review aimed...

    Authors: Ewan Gray, Anna Donten, Katherine Payne and Peter S. Hall

    Citation: Systematic Reviews 2018 7:142

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  42. Content type: Protocol

    Type 2 diabetes mellitus (T2DM) remains a public health problem in low-income countries, including African countries. Risk factors of this disease in Africa are still unclear. This study will examine the modif...

    Authors: Ayuba Issaka, Yin Paradies and Christopher Stevenson

    Citation: Systematic Reviews 2018 7:139

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  43. Content type: Research

    To assess the financial burden due to out of pocket (OOP) payments, two mutually exclusive approaches have been used: catastrophic health expenditure (CHE) and impoverishment. Sub-Saharan African (SSA) countri...

    Authors: Purity Njagi, Jelena Arsenijevic and Wim Groot

    Citation: Systematic Reviews 2018 7:136

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  44. Content type: Protocol

    Skin and soft tissue infections (SSTIs) in hospital and community settings impose a substantial socio-economic burden. Therapeutic uncertainty due to the availability of a wide range of antibiotics and the nee...

    Authors: Jessica J. Bartoszko, Dominik Mertz, Lehana Thabane and Mark Loeb

    Citation: Systematic Reviews 2018 7:138

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  45. Content type: Research

    Lean is a quality improvement management system from the Toyota manufacturing industry. Since the early 2000’s, Lean has been used as an intervention for healthcare improvement. Lean is intended to reduce cost...

    Authors: Rachel Flynn, Amanda S. Newton, Thomas Rotter, Dawn Hartfield, Sarah Walton, Michelle Fiander and Shannon D. Scott

    Citation: Systematic Reviews 2018 7:137

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  47. Content type: Protocol

    Fear of cancer recurrence (FCR) is reportedly common, persistent, associated with significant morbidity and often higher in cancer caregivers than cancer patients. This review will summarise empirical research...

    Authors: Stuart Leske, Allan Ben Smith, Sylvie D. Lambert and Afaf Girgis

    Citation: Systematic Reviews 2018 7:134

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  48. Content type: Protocol

    Childhood obesity has become a global epidemic irrespective of the socioeconomic status of a country or nation. Obesity increases the risk of various diseases in children, for example asthma, sleep apnea, bone...

    Authors: Abdul Wajid, Muhammad Kashif Mughal, Deborah McNeil, Helen Lee Robertson and Dawn Kingston

    Citation: Systematic Reviews 2018 7:133

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  49. Content type: Protocol

    Breast cancer and its treatment can have many physical and psychological effects on affected women. Women’s personal goals may provide insight into their priorities and motivations in the context of breast can...

    Authors: Andrea Chow, Justin Presseau, Iris Perelman, Lindsey Sikora and Dean Fergusson

    Citation: Systematic Reviews 2018 7:132

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  50. Content type: Protocol

    Unsafe abortion is a neglected public health problem contributing for 13% of maternal death worldwide. In Africa, 99% of abortions are unsafe resulting in one maternal death per 150 cases. The prevalence of un...

    Authors: Merhawi Gebremedhin, Agumasie Semahegn, Tofik Usmael and Gezahegn Tesfaye

    Citation: Systematic Reviews 2018 7:130

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Systematic Reviews

ISSN: 2046-4053