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  1. Lower respiratory tract infection (LRTI) caused by respiratory syncytial virus (RSV) has been associated with greater risk of recurrent wheezing and subsequent asthma. However, it is still unclear whether this...

    Authors: Lauren Alexandra Quinn, Michael D. Shields and Helen E. Groves
    Citation: Systematic Reviews 2019 8:333
  2. Our understanding of recovery after moderate-to-severe traumatic brain injury (TBI) has shifted. Until recently, it was presumed that following a period of acute neurological vulnerability, the brain remained ...

    Authors: Bhanu Sharma, Alana T. Changoor, Leanne Monteiro, Brenda Colella and Robin E. A. Green
    Citation: Systematic Reviews 2019 8:332
  3. Stroke is a leading cause of death and disability worldwide. Identifying the aetiology of ischaemic stroke is essential in order to initiate appropriate and timely secondary prevention measures to reduce the r...

    Authors: Emma P. Bray, Naoimh E. McMahon, Munirah Bangee, A. Hakam Al-Khalidi, Valerio Benedetto, Umesh Chauhan, Andrew J. Clegg, Rachel F. Georgiou, Josephine Gibson, Deirdre A. Lane, Gregory Y. H. Lip, Elizabeth Lightbody, Alakendu Sekhar, Kausik Chatterjee and Caroline L. Watkins
    Citation: Systematic Reviews 2019 8:331
  4. Hypertension, type 2 diabetes mellitus and cardiovascular disease are among the leading causes of mortality globally. Exercise is one of the commonly recommended interventions/preventions for hypertension, typ...

    Authors: Anupa Rijal, Emil Eik Nielsen, Bianca Hemmingsen, Dinesh Neupane, Peter Haulund Gæde, Michael Hecht Olsen and Janus Christian Jakobsen
    Citation: Systematic Reviews 2019 8:330
  5. Pyrazinamide (PZA) is a key component of current and future regimens for tuberculosis (TB). Inclusion of PZA at higher doses and for longer durations may improve efficacy outcomes but must be balanced against ...

    Authors: James D. Millard, Elizabeth A. Mackay, Laura J. Bonnett and Geraint R. Davies
    Citation: Systematic Reviews 2019 8:329
  6. Research shows that there are inadequate interventions in resource-limited settings that could enable women of reproductive age to access and use health services in those settings. The main objective of this s...

    Authors: Joyce T. Shatilwe and Tivani P. Mashamba-Thompson
    Citation: Systematic Reviews 2019 8:328
  7. Over the past decades, there has been an increase in overweight and obesity in women of childbearing age, as well as the general population. Overweight and obesity are related to a later, increased risk of typ...

    Authors: Pernille Kjaergaard Christiansen, Mette Maria Skjøth, Mette Juel Rothmann, Christina Anne Vinter, Ronald Francis Lamont and Eva Draborg
    Citation: Systematic Reviews 2019 8:327
  8. The use of substances is a growing concern in Ethiopia, and their impacts on younger generation have been a concern of different professionals. Even though students are at high-risk of substance abuse, there i...

    Authors: Hirbo Shore Roba, Addisu Shunu Beyene, Asnake Ararsa Irenso and Berhe Gebremichael
    Citation: Systematic Reviews 2019 8:326
  9. Living systematic reviews (LSRs) offer an approach to keeping high-quality evidence synthesis continually up to date, so the most recent, relevant and reliable evidence can be used to inform policy and practic...

    Authors: Tanya Millard, Anneliese Synnot, Julian Elliott, Sally Green, Steve McDonald and Tari Turner
    Citation: Systematic Reviews 2019 8:325
  10. Fatigue is a common symptom in cancer patients that can persist beyond the curative treatment phase. This systematic review evaluated the effectiveness of psychological interventions for cancer-related fatigue...

    Authors: T. K. Corbett, A. Groarke, D. Devane, E. Carr, J. C. Walsh and B. E. McGuire
    Citation: Systematic Reviews 2019 8:324
  11. Severe acute malnutrition affects more than 20 million children. Africa is pointed out as a region where the problem is highly prevalent. There were individual studies on the recovery rate and its determinants...

    Authors: Kassahun Gebeyehu Yazew, Chanyalew Worku Kassahun, Amare Wondim Ewnetie, Habtamu Kerebih Mekonen and Endalamaw Salilew Abagez
    Citation: Systematic Reviews 2019 8:323
  12. Over the past decade, mesenchymal stromal cells have been increasingly investigated for their therapeutic potential in several different illnesses. However, cell therapy can be limited by potentially serious a...

    Authors: Alvin Tieu, Mitchell Slobodian, Dean A. Fergusson, Joshua Montroy, Dylan Burger, Duncan J. Stewart, Risa Shorr, David S. Allan and Manoj M. Lalu
    Citation: Systematic Reviews 2019 8:322
  13. Trastuzumab is a monoclonal antibody for patients with HER2 (human epidermal growth factor receptor 2)-positive breast cancer, which is added to regular treatment and reduces mortality. Originally, trastuzumab...

    Authors: Miriam Van den Nest, Anna Glechner, Maria Gold and Gerald Gartlehner
    Citation: Systematic Reviews 2019 8:321
  14. There has been increased interest in the role of cannabis for treating medical conditions. The availability of different cannabis-based products can make the side effects of exposure unpredictable. We sought t...

    Authors: Misty Pratt, Adrienne Stevens, Micere Thuku, Claire Butler, Becky Skidmore, L. Susan Wieland, Mark Clemons, Salmaan Kanji and Brian Hutton
    Citation: Systematic Reviews 2019 8:320
  15. The World Health Organization describes the perpetuation of human rights violations against people with mental health problems as a global emergency. Despite this observation, recent studies suggest that coerc...

    Authors: Pierre Pariseau-Legault, Sandrine Vallée-Ouimet, Marie-Hélène Goulet and Jean-Daniel Jacob
    Citation: Systematic Reviews 2019 8:318
  16. The growing number of medical literature and textual data in online repositories led to an exponential increase in the workload of researchers involved in citation screening for systematic reviews. This work a...

    Authors: Corrado Lanera, Paola Berchialla, Abhinav Sharma, Clara Minto, Dario Gregori and Ileana Baldi
    Citation: Systematic Reviews 2019 8:317
  17. The global prevalence of people living with dementia is expected to increase exponentially and yet evidence suggests gaps in dementia-specific knowledge amongst practitioners. Evidence-based learning approache...

    Authors: Kevin Muirhead, Leah Macaden, Charlotte Clarke, Keith Smyth, Rob Polson and Chris O’Malley
    Citation: Systematic Reviews 2019 8:316
  18. Emergency and disaster are on the rise in the world. One of the most important components of disaster risk management is the early warning system. Studies have shown divergent models of warning systems with di...

    Authors: Hamid Reza Khankeh, Seyed Hossein Hosseini, Mehrdad Farrokhi, Mohammad Ali Hosseini and Nasir Amanat
    Citation: Systematic Reviews 2019 8:315
  19. To meet global targets for the treatment of HIV, high-prevalence countries are launching or expanding differentiated models of service delivery (DSD) for antiretroviral therapy (ART). Ongoing studies report on...

    Authors: Lawrence Long, Salome Kuchukhidze, Sophie Pascoe, Brooke Nichols, Refiloe Cele, Caroline Govathson, Amy Huber, David Flynn and Sydney Rosen
    Citation: Systematic Reviews 2019 8:314
  20. Smoking remains a major public health concern. School-based social networks influence uptake of smoking among peers. During the past two decades, the UK macro-systemic context within which schools are nested a...

    Authors: H. J. Littlecott, J. Hawkins, M. Mann, G. J. Melendez-Torres, F. Dobbie and G. Moore
    Citation: Systematic Reviews 2019 8:313
  21. Intimate partner violence among young women continues to be a worldwide concern. Globally, a considerable number of studies reported numerous factors that influence intimate partner violence among the young. T...

    Authors: Maria Suzana B. Maguele and Nelisiwe Khuzwayo
    Citation: Systematic Reviews 2019 8:312
  22. Mechanically ventilated patients in the intensive care unit (ICU) experience profound communication impairment, placing them at risk for poor physical and psychological outcomes. Patient communication strategi...

    Authors: Laura Istanboulian, Louise Rose, Yana Yunusova, Franklin Gorospe and Craig Dale
    Citation: Systematic Reviews 2019 8:311
  23. Type 2 diabetes mellitus (T2DM) is a worldwide epidemic, and while its etiology is polygenic, the role of environmental contaminant exposure in T2DM pathogenesis is of increasing importance. However, the evide...

    Authors: Julia Hildebrand, Swarni Thakar, Tonya-Leah Watts, Laura Banfield, Lehana Thabane, Joseph Macri, Stephen Hill and M. Constantine Samaan
    Citation: Systematic Reviews 2019 8:309
  24. Metabolic syndrome (MetS) is defined as an accumulation of risk factors that include chronic hypertension, dyslipidaemia, insulin resistance and obesity and leads to an increased risk for diabetes, cardiovascu...

    Authors: Philip Norris, Bianca Viljoen, Nicholas Ralph, Jeff Gow and Natalie Silvey
    Citation: Systematic Reviews 2019 8:308
  25. There is a widespread belief that information technologies will improve diagnosis, treatment and care. Evidence about their effectiveness in health care is, however, mixed. It is not clear why this is the case...

    Authors: Justin Keen, Joanne Greenhalgh, Rebecca Randell, Peter Gardner, Justin Waring, Roberta Longo, Jon Fistein, Maysam Abdulwahid, Natalie King and Judy Wright
    Citation: Systematic Reviews 2019 8:307
  26. Sepsis is a major cause of morbidity and mortality among neonates and infants. Antibiotics are a central part of the first line treatment for sepsis in neonatal intensive care units worldwide. However, the evi...

    Authors: Steven Kwasi Korang, Sanam Safi, Christian Gluud, Ulrik Lausten-Thomsen and Janus C. Jakobsen
    Citation: Systematic Reviews 2019 8:306
  27. Practitioner-level implementation interventions such as audit and feedback, communities of practice, and local opinion leaders have shown potential to change nurses’ behaviour in clinical practice and improve ...

    Authors: Guillaume Fontaine, Sylvie Cossette, Marc-André Maheu-Cadotte, Marie-France Deschênes, Geneviève Rouleau, Andréane Lavallée, Catherine Pépin, Ariane Ballard, Gabrielle Chicoine, Alexandra Lapierre, Patrick Lavoie, Jérémie Blondin and Tanya Mailhot
    Citation: Systematic Reviews 2019 8:305
  28. Antibiotic resistance is a global public health threat. Water from human activities is collected at wastewater treatment plants where processes often do not sufficiently neutralize antibiotic resistant bacteri...

    Authors: Daloha Rodríguez-Molina, Petra Mang, Heike Schmitt, Mariana Carmen Chifiriuc, Katja Radon and Laura Wengenroth
    Citation: Systematic Reviews 2019 8:304
  29. Physical inactivity is the fourth leading risk factor for global mortality. Reducing sedentary behaviour and increasing physical activity are efficacious for improving many physical and mental health condition...

    Authors: Jean-Pierre Laake and Joanna Fleming
    Citation: Systematic Reviews 2019 8:303
  30. Chinese herbal medicines (CHMs) are the major interventions of traditional Chinese medicine (TCM), which are typically administered as either single herbs or formulas. The Cochrane systematic reviews (SRs) of ...

    Authors: Xuan Zhang, Qi-Ying Aixinjueluo, Si-Yao Li, Lisa-L Song, Chung-Tai Lau, Ran Tan and Zhao-Xiang Bian
    Citation: Systematic Reviews 2019 8:302
  31. In the U.S., Hispanic women experience a disproportionate rate of obesity and obesity-related chronic diseases. At the same time, Hispanic women remain considerably underrepresented in behavioral weight loss i...

    Authors: Kristin E. Morrill, Melissa Lopez-Pentecost, Guadalupe Ballesteros, Jeanne L. Pfander, Melanie D. Hingle, Yann C. Klimentidis, Cynthia A. Thomson and David O. Garcia
    Citation: Systematic Reviews 2019 8:301
  32. Fathers are under-represented in research and programs addressing early childhood health and development. Recruiting fathers into these interventions can be hampered for multiple reasons, including recruitment...

    Authors: Elizabeth M. Keys, Jill M. Norris, Emily E. Cameron, Katherine S. Bright, Lianne M. Tomfohr-Madsen and Karen M. Benzies
    Citation: Systematic Reviews 2019 8:300
  33. Opioid agonist maintenance treatment (OAMT) is a first-line treatment for heroin dependence, but its effectiveness has been assessed primarily through clinical outcomes with a limited attention to patient pers...

    Authors: Ivan Solà, Joan Trujols, Elisa Ribalta, Saul Alcaraz, Gemma Robleda, Clara Selva Olid and José Pérez de los Cobos
    Citation: Systematic Reviews 2019 8:299
  34. The present protocol was designed for a systematic review and meta-analysis aimed at determining the association of telomere length with substance use disorders with the exclusion of nicotine addiction, and to...

    Authors: Fernando Navarro-Mateu, María Rubio-Aparicio, Pedro Cayuela, Francisco-Javier Álvarez, Agustín Roca-Vega, María Dolores Chirlaque, María Luisa Cayuela, Mathilde Husky, Salvador Martínez and Julio Sánchez-Meca
    Citation: Systematic Reviews 2019 8:298
  35. Prevention of antenatal and postnatal depression is crucial, given its high prevalence and severe consequences. Although several systematic reviews and meta-analyses have examined the effects of psychological ...

    Authors: Naonori Yasuma, Zui Narita, Natsu Sasaki, Erika Obikane, Junpei Sekiya, Takuma Inagawa, Aiichiro Nakajima, Yuji Yamada, Ryuichi Yamazaki, Asami Matsunaga, Tomomi Saito, Kazuhiro Watanabe, Kotaro Imamura, Norito Kawakami and Daisuke Nishi
    Citation: Systematic Reviews 2019 8:297
  36. Active school travel by bike may provide appropriate means to promote physical activity through commuting to and from school, expanding the mobility during leisure time, and integrating a lifelong positive beh...

    Authors: Dorothea M. I. Schönbach, Teatske M. Altenburg, Mai J. M. Chinapaw, Adilson Marques and Yolanda Demetriou
    Citation: Systematic Reviews 2019 8:296
  37. A healthy and productive health workforce is central to a well-functioning health system. However, health workers are at high risk of poor psychological wellbeing due to their particularly strenuous work deman...

    Authors: Julia Lohmann, Denny John and Aso Dzay
    Citation: Systematic Reviews 2019 8:294
  38. Exosomes may have critical roles in the maternal-embryo cross-talk for the recognition and maintenance of pregnancy during maternal aging. Exosomes have the capability to carry developmental signaling molecule...

    Authors: Halimeh Mobarak, Reza Rahbarghazi, Francesca Lolicato, Mohammad Heidarpour, Fariba Pashazadeh, Mohammad Nouri and Mahdi Mahdipour
    Citation: Systematic Reviews 2019 8:293
  39. The implementation of trauma systems in many high-income countries over the last 50 years has led to important reductions in injury mortality and disability in many healthcare jurisdictions. Injury organizatio...

    Authors: Brice Batomen, Lynne Moore, Mabel Carabali, Pier-Alexandre Tardif, Howard Champion and Arijit Nandi
    Citation: Systematic Reviews 2019 8:292
  40. Nutritional therapy practice guidelines are designed to improve nutritional practices and thus the delivery of nutritional therapy in critically ill patients. However, they are not implemented despite the stro...

    Authors: Nomaxabiso M. Mooi and Busisiwe P. Ncama
    Citation: Systematic Reviews 2019 8:291
  41. Childhood adiposity has increased dramatically in the last few decades and is an important predictor of adulthood chronic disease. Later eating rhythm, termed night eating (NE), is increasingly prevalent in ad...

    Authors: Mengxuan Zou, Kate Northstone, Rachel Perry, Laura Johnson and Sam Leary
    Citation: Systematic Reviews 2019 8:290
  42. Since the deinstitutionalization policy, in psychiatric hospitals, the care of patients with schizophrenia was left to their families which has been imposing a heavy burden on them. Family caregiver burden cou...

    Authors: Zahra Tamizi, Masoud Fallahi-Khoshknab, Asghar Dalvandi, Farahnaz Mohammadi-Shahboulaghi, Eesa Mohammadi and Enayatollah Bakhshi
    Citation: Systematic Reviews 2019 8:289
  43. Obesity and its consequences are worldwide epidemic problem; therefore, studies with strategies and mechanisms that favor weight loss to improve outcomes in health are necessary. Effects of mushrooms on body w...

    Authors: Denise Grotto, Isabella Ferreira Camargo, Katia Kodaira, Lauren Giustti Mazzei, Juliana Castro, Raquel Andrade Leite Vieira, Cristiane de Cásia Bergamaschi and Luciane Cruz Lopes
    Citation: Systematic Reviews 2019 8:288
  44. Inflammation in anterior uveitis is characterised by breakdown of the blood-ocular barrier, which allows leakage of blood constituents of higher molecular weight into the aqueous humour. In routine clinical ca...

    Authors: Thomas W. McNally, Xiaoxuan Liu, Sophie Beese, Pearse A. Keane, David J. Moore and Alastair K. Denniston
    Citation: Systematic Reviews 2019 8:287
  45. Despite advances in resuscitation care, mortality rates following cardiac arrest (CA) remain high. Between one-quarter (in-hospital CA) and two-thirds (out of hospital CA) of patients admitted comatose to inte...

    Authors: Alex Monk and Shashank Patil
    Citation: Systematic Reviews 2019 8:286
  46. Despite existing best practice care recommendations for addressing tobacco smoking, alcohol consumption and weight management in preconception and antenatal care, such recommendations are often not implemented...

    Authors: Emma Doherty, Melanie Kingsland, Luke Wolfenden, John Wiggers, Julia Dray, Jenna Hollis, Elizabeth J. Elliott, Justine B. Daly, Kylie A. Bailey, John Attia, Mandy Hunter, Ian Symonds, Belinda Tully, Danika Tremain and Rebecca K. Hodder
    Citation: Systematic Reviews 2019 8:285
  47. Oropharyngeal dysphagia or swallowing difficulties are common in acute care and critical care, affecting 47% of hospitalised frail elderly, 50% of acute stroke patients and approximately 62% of critically ill ...

    Authors: Sallyanne Duncan, Jennifer Mc Gaughey, Richard Fallis, Daniel F. McAuley, Margaret Walshe and Bronagh Blackwood
    Citation: Systematic Reviews 2019 8:283

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