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  1. Vitamin D (vitD) deficiency is a global childhood health problem. Food fortification is a promising strategy to curb vitD deficiency. We aimed to assess the effectiveness of utilizing vitD fortification in sta...

    Authors: Reem Al Khalifah, Rawan Alsheikh, Yossef Alnasser, Rana Alsheikh, Nora Alhelali, Ammar Naji and Nouf Al Backer
    Citation: Systematic Reviews 2020 9:144
  2. Health practitioners from different professions, and with differing competencies, need to collaborate to provide quality care. Competencies in interprofessional working need developing in undergraduate educati...

    Authors: Renée Allvin, Carl Thompson and Samuel Edelbring
    Citation: Systematic Reviews 2020 9:142
  3. There is no consensus on the role of inflammatory markers in identifying chorioamnionitis in preterm prelabour rupture of membranes (PPROM). We set out to evaluate the accuracy of maternal blood C-reactive pro...

    Authors: Angela Koech Etyang, Geoffrey Omuse, Abraham Mwaniki Mukaindo and Marleen Temmerman
    Citation: Systematic Reviews 2020 9:141
  4. A model that can predict treatment response for a patient with specific baseline characteristics would help decision-making in personalized medicine. The aim of the study is to develop such a model in the trea...

    Authors: Yan Luo, Konstantina Chalkou, Ryo Yamada, Satoshi Funada, Georgia Salanti and Toshi A. Furukawa
    Citation: Systematic Reviews 2020 9:140
  5. US opioid prescribing and use escalated over the last two decades, with parallel increases in opioid misuse, opioid-related deaths, and concerns about diversion. Postoperatively prescribed opioids contribute t...

    Authors: Lori Schirle, Amanda L. Stone, Matthew C. Morris, Sarah S. Osmundson, Philip D. Walker, Mary S. Dietrich and Stephen Bruehl
    Citation: Systematic Reviews 2020 9:139
  6. Alcohol use is a challenging problem which attributes to more than 5% of the overall global burden of disease. It is more common among persons with HIV infection than the general population. Although there are...

    Authors: Birhanie Mekuriaw, Zelalem Belayneh, Alemayehu Molla and Tsegaye Mehare
    Citation: Systematic Reviews 2020 9:138
  7. Diabetes is a highly prevalent chronic disease that places a large burden on individuals and health care systems. Models predicting the risk (also called predictive models) of other conditions often compare pe...

    Authors: Ruth Ndjaboue, Imen Farhat, Carol-Ann Ferlatte, Gérard Ngueta, Daniel Guay, Sasha Delorme, Noah Ivers, Baiju R. Shah, Sharon Straus, Catherine Yu and Holly O. Witteman
    Citation: Systematic Reviews 2020 9:137
  8. Work-related musculoskeletal disorders impose a significant and most often underappreciated burden to the individual, nation, healthcare system, and society as a whole. To the best of our knowledge, there is a...

    Authors: Tsiwaye Gebreyesus, Kalkidan Nigussie, Moges Gashaw and Balamurugan Janakiraman
    Citation: Systematic Reviews 2020 9:136
  9. Metabolic syndrome is a constellation of various cardiovascular and type 2 diabetes risk factors, such as abdominal obesity, atherogenic dyslipidemia, high blood pressure, and high blood glucose, but its preva...

    Authors: Nicholas Kofi Adjei, Florence Samkange-Zeeb, Mihiretu Kebede, Maham Saleem, Thomas L. Heise and Hajo Zeeb
    Citation: Systematic Reviews 2020 9:134
  10. Community-based peer and community health worker-led diabetes self-management programs (COMP-DSMP) can benefit diabetes care, but the supporting evidence has been inadequately assessed. This systematic review ...

    Authors: Mahmoud Werfalli, Peter J. Raubenheimer, Mark Engel, Alfred Musekiwa, Kirsten Bobrow, Nasheeta Peer, Cecilia Hoegfeldt, Sebastiana Kalula, Andre Pascal Kengne and Naomi S. Levitt
    Citation: Systematic Reviews 2020 9:133
  11. Network meta-analyses (NMAs) of psoriasis treatments, undertaken as part of the NICE Single Technology Appraisal (STA) process, have included heterogeneous studies. When there is inconsistency or heterogeneity...

    Authors: Ros Wade, Sahar Sharif-Hurst and Sofia Dias
    Citation: Systematic Reviews 2020 9:132
  12. Delirium is an acute confusional state, common in critical illness and associated with cognitive decline. There is no effective pharmacotherapy to prevent or treat delirium, although it is scientifically plaus...

    Authors: Cathrine A. McKenzie, Valerie J. Page, W. David Strain, Bronagh Blackwood, Marlies Ostermann, David Taylor, Peter E. Spronk and Daniel F. McAuley
    Citation: Systematic Reviews 2020 9:131
  13. Despite the enormous financial and humanistic burden of chronic low back pain (CLBP), there is little consensus on what constitutes the best treatment options from a multitude of competing interventions. The o...

    Authors: Trevor Thompson, Sofia Dias, Damian Poulter, Sharon Weldon, Lucy Marsh, Claire Rossato, Jae Il Shin, Joseph Firth, Nicola Veronese, Elena Dragioti, Brendon Stubbs, Marco Solmi, Christopher G. Maher, Andrea Cipriani and John P. A. Ioannidis
    Citation: Systematic Reviews 2020 9:130
  14. According to the UK’s Office for National Statistics, England and Wales reported a 2.9% increase in sexual aggression cases (3.4 million females and 631,000 males) between 2009 and 2019. In Scotland, sexual ag...

    Authors: Delarise Maud Mulqueeny, Jennifer Roberts and Senzelokuhle Mpumelelo Nkabini
    Citation: Systematic Reviews 2020 9:129
  15. Healthy aging (HA) is a contemporary challenge for population health worldwide. Electronic health (e-Health) interventions have the potential to support empowerment and education of adults aged 50 and over.

    Authors: Ronald Buyl, Idrissa Beogo, Maaike Fobelets, Carole Deletroz, Philip Van Landuyt, Samantha Dequanter, Ellen Gorus, Anne Bourbonnais, Anik Giguère, Kathleen Lechasseur and Marie-Pierre Gagnon
    Citation: Systematic Reviews 2020 9:128
  16. Six core behavioural risk factors (poor diet, physical activity, sedentary behaviour, alcohol misuse, smoking and unhealthy sleep patterns) have been identified as strong determinants of chronic disease, such ...

    Authors: Louise Thornton, Bridie Osman, Annie B. Wescott, Matthew Sunderland, Katrina Champion, Olivia Green, Frances Kay-Lambkin, Tim Slade, Nickie Newton, Cath Chapman, Maree Teesson, Katherine Mills, Louise Birrell, David Lubans, Pepijn Van de Ven, John Torous…
    Citation: Systematic Reviews 2020 9:127
  17. Perinatal loss is a traumatic and complex experience that contributes to negative maternal psychological states and adverse outcomes impacting fetal development, maternal-fetal/infant bonding, marital/partner ...

    Authors: Elyse M. Charrois, Katherine S. Bright, Abdul Wajid, Muhammad Kashif Mughal, K. Alix Hayden and Dawn Kingston
    Citation: Systematic Reviews 2020 9:125
  18. Current understandings of the etiology of traumatic brain injury (TBI) and the trajectory of care significantly lack consideration for the inclusion of Black populations. The global prevalence of TBI is increa...

    Authors: Samira Omar, LLana James, Angela Colantonio and Stephanie A. Nixon
    Citation: Systematic Reviews 2020 9:124
  19. Barriers to receiving optimal healthcare exist for Indigenous populations globally for a range of reasons. To overcome such barriers and enable greater access to basic and specialist care, developments in info...

    Authors: Rachel Reilly, Jacqueline Stephens, Jasmine Micklem, Catalin Tufanaru, Stephen Harfield, Ike Fisher, Odette Pearson and James Ward
    Citation: Systematic Reviews 2020 9:123
  20. Chronic musculoskeletal pain represents an enormous burden in society. Best-practice care for chronic musculoskeletal pain suggests adoption of self-management strategies. Telehealth interventions (e.g., video...

    Authors: Lívia G. Fernandes, Hemakumar Devan, Steven J. Kamper, Christopher M. Williams and Bruno T. Saragiotto
    Citation: Systematic Reviews 2020 9:122
  21. First responders are a high-risk population for occupational stress injuries as they often encounter prolonged stress within their line of work. The aim of this rapid overview of reviews is to summarize existi...

    Authors: Jesmin Antony, Raman Brar, Paul A. Khan, Marco Ghassemi, Vera Nincic, Jane P. Sharpe, Sharon E. Straus and Andrea C. Tricco
    Citation: Systematic Reviews 2020 9:121
  22. Continuous glucose monitorings (CGMs) have been used to manage diabetes with reasonable glucose control amongst patients with type 2 diabetes (T2D) in recent decades. CGMs measure interstitial fluid glucose le...

    Authors: Mingyue Zheng, Yunting Luo, Wei Lin, Adeel Khoja, Qian He, Shenqiao Yang, Xuan Zhao and Peng Hu
    Citation: Systematic Reviews 2020 9:120
  23. With an increase in wildfire activity across the globe and growing numbers of personnel involved each year, it is necessary to explore the health impacts of occupational exposure to wildfires and the practices...

    Authors: Erica Koopmans, Trina Fyfe, Mike Eadie and Chelsea A. Pelletier
    Citation: Systematic Reviews 2020 9:119
  24. Peripheral nerves are constant targets of traumatic injury which may result in neurotmesis and which invariably requires surgical treatment. In view of this, tissue engineering studies developed biomaterials w...

    Authors: Ana Camila Nobre de Lacerda Brito, Sara Emanuely Veríssimo Santos, Wilayane Alves Martins, Paulo César da Silva Queiroz, Wenddy Wyllie Damascena Sougey, Paula Ketilly Nascimento Alves, Kalline Lourenço Ribeiro, Maria Danielly Lima de Oliveira and Sílvia Regina Arruda de Moraes
    Citation: Systematic Reviews 2020 9:118
  25. Meta-analysts rely on the availability of data from previously conducted studies. That is, they rely on primary study authors to register their outcome data, either in a study’s text or on publicly available w...

    Authors: Joshua R. Polanin, Dorothy L. Espelage, Jennifer K. Grotpeter, Alberto Valido, Katherine M. Ingram, Cagil Torgal, America El Sheikh and Luz E. Robinson
    Citation: Systematic Reviews 2020 9:116
  26. This work aimed to identify studies of interventions seeking to address mental health inequalities, studies assessing the economic impact of such interventions and factors which act as barriers and those that ...

    Authors: Laura-Louise Arundell, Helen Greenwood, Helen Baldwin, Eleanor Kotas, Shubulade Smith, Kasia Trojanowska and Chris Cooper
    Citation: Systematic Reviews 2020 9:115
  27. Neurotrauma is an important global health problem. The largest cause of neurotrauma worldwide is road traffic collisions (RTCs), particularly in low- and middle-income countries (LMICs). Neurotrauma and RTCs a...

    Authors: Santhani M Selveindran, Tamara Tango, Muhammad Mukhtar Khan, Daniel Martin Simadibrata, Peter J. A. Hutchinson, Carol Brayne, Christine Hill, Franco Servadei, Angelos G. Kolias, Andres M. Rubiano, Alexis J. Joannides and Hamisi K. Shabani
    Citation: Systematic Reviews 2020 9:114
  28. Water, sanitation, and hygiene interventions often fail to show long-term impact on diarrhoeal and/or intestinal parasite risk in many low- and middle-income countries. Less attention has been paid to wider co...

    Authors: Benn Sartorius, Hugo Legge and Rachel Pullan
    Citation: Systematic Reviews 2020 9:113
  29. The literature on the implementation of knowledge products is extensive. However, this literature is still difficult to interpret for policymakers and other stakeholders when faced with choosing implementation...

    Authors: Hervé Tchala Vignon Zomahoun, José Massougbodji, André Bussières, Aliki Thomas, Dahlia Kairy, Claude Bernard Uwizeye, Nathalie Rheault, Ali Ben Charif, Ella Diendéré, Léa Langlois, Sébastien Tchoubi, Serigne Abib Gaye and France Légaré
    Citation: Systematic Reviews 2020 9:112
  30. To date multimorbidity has not received much attention in health policies, even though multiple chronic diseases put high demands on the health care system in industrial nations. Enormous costs of care and a p...

    Authors: Simone Schweda and Inga Krauss
    Citation: Systematic Reviews 2020 9:110
  31. Environmental factors such as pollution, pesticide exposure and socio-demographic location have been implicated as a pressure capable of altering genetic make-up. Altered genetic sequence of genes encoding enz...

    Authors: Nkosinathi Banhela, Pragalathan Naidoo and Saloshni Naidoo
    Citation: Systematic Reviews 2020 9:109
  32. COVID-19 is a rapidly spreading virus infection that has quickly caused extensive burden to individual, families, countries, and the globe. No intervention has yet been proven effective for the treatment of CO...

    Authors: Sophie Juul, Niklas Nielsen, Peter Bentzer, Areti Angeliki Veroniki, Lehana Thabane, Adam Linder, Sarah Klingenberg, Christian Gluud and Janus Christian Jakobsen
    Citation: Systematic Reviews 2020 9:108
  33. Endovascular therapy is a fundamental treatment for peripheral arterial disease. However, the success rate of endovascular therapy remains poor, as a third of patients with critical limb ischemia ultimately re...

    Authors: Mark Rockley, Prasad Jetty and George Wells
    Citation: Systematic Reviews 2020 9:107
  34. Antibiotics are prescribed frequently for upper respiratory tract infections (URTIs) even though most URTIs do not require antibiotics. This over-prescription contributes to antibiotic resistance which is a ma...

    Authors: Sameh Mortazhejri, Patrick Jiho Hong, Ashley M. Yu, Brian Younho Hong, Dawn Stacey, R. Sacha Bhatia and Jeremy M. Grimshaw
    Citation: Systematic Reviews 2020 9:106
  35. Despite recent improvements in the burden of cardiovascular disease (CVD) in the UK, deaths from CVD are relatively high compared with other high-income countries. An estimated 7 million people in the UK are l...

    Authors: Olalekan A. Uthman, Lena Al-Khudairy, Chidozie U. Nduka, Rachel Court, Hema Mistry, G . J. Melendez-Torres, Sian Taylor-Phillips and Aileen Clarke
    Citation: Systematic Reviews 2020 9:105
  36. With technological advances, there has been increasing interest in developing contactless and/or non-invasive wearable technologies that continuously monitor vital signs in the clinical setting, and in particu...

    Authors: Peter Y. Chan, John McNeil, Tam Nguyen, Nicholas Ryan and Ingrid Hopper
    Citation: Systematic Reviews 2020 9:104
  37. Vascular endothelial growth factor (VEGF) is one of the angiogenesis regulators, which plays an important role in tumor angiogenesis and tumor progression. Current studies have found that VEGF plays an importa...

    Authors: Mingzhu Song, Huiping Wang and Qianling Ye
    Citation: Systematic Reviews 2020 9:103
  38. A growing number of studies suggest that social isolation and loneliness are associated with premature mortality and are more prevalent among people with mental illness than in the general population, outlinin...

    Authors: Adriano Winterton, Linn Rødevand, Lars T. Westlye, Nils Eiel Steen, Ole A. Andreassen and Daniel S. Quintana
    Citation: Systematic Reviews 2020 9:102
  39. Many epidemiological studies have investigated the prevalence of type 2 diabetes in individuals with a psychiatric disorder. In an umbrella review, we aim to systematically summarize existing systematic review...

    Authors: N. Lindekilde, S. Scheuer, F. Rutters, J. E. Henriksen, K. H. Rubin, M. Lasgaard, G. S. Andersen and F. Pouwer
    Citation: Systematic Reviews 2020 9:101
  40. The fourth meeting of the International Collaboration for Automation of Systematic Reviews (ICASR) was held 5–6 November 2019 in The Hague, the Netherlands. ICASR is an interdisciplinary group whose goal is to...

    Authors: Annette M. O’Connor, Paul Glasziou, Michele Taylor, James Thomas, René Spijker and Mary S. Wolfe
    Citation: Systematic Reviews 2020 9:100
  41. Cotton workers are exposed to various hazards in the textile industry that might result in different ailments including hypertension (HTN). However, few attempts have been made to systematically review the pre...

    Authors: Naureen Akber Ali and Anam Shahil Feroz
    Citation: Systematic Reviews 2020 9:99
  42. Gasless laparoscopy, developed in the early 1990s, was a means to minimize the clinical and financial challenges of pneumoperitoneum and general anaesthesia. It has been used in a variety of procedures such as...

    Authors: Haitham Shoman, Simone Sandler, Alexander Peters, Ameer Farooq, Magdalen Gruendl, Shauna Trinh, James Little, Alex Woods, William Bolton, Abubakar Abioye and David Ljungman
    Citation: Systematic Reviews 2020 9:98
  43. Network meta-analysis (NMA) has rapidly grown in use during the past decade for the comparison of healthcare interventions. While its general use in the comparison of conventional medicines has been studied pr...

    Authors: Misty Pratt, Susan Wieland, Nadera Ahmadzai, Claire Butler, Dianna Wolfe, Kusala Pussagoda, Becky Skidmore, Argie Veroniki, Patricia Rios, Andrea C. Tricco and Brian Hutton
    Citation: Systematic Reviews 2020 9:97
  44. In children and adolescents, anxiety disorders (ADs) are among the most prevalent mental disorders. While there is a solid empirical foundation to support CBT as an evidence-based treatment for childhood ADs, ...

    Authors: Kathrin Schopf, Cornelia Mohr, Michael W. Lippert, Katharina Sommer, Andrea Hans Meyer and Silvia Schneider
    Citation: Systematic Reviews 2020 9:96
  45. Acute hypoxemic respiratory failure is one of the leading causes of intensive care unit admission and is associated with high mortality. Noninvasive oxygenation strategies such as high-flow nasal cannula, stan...

    Authors: Bruno L. Ferreyro, Federico Angriman, Laveena Munshi, Lorenzo Del Sorbo, Niall D. Ferguson, Bram Rochwerg, Michelle J. Ryu, Refik Saskin, Hannah Wunsch, Bruno R. da Costa and Damon C. Scales
    Citation: Systematic Reviews 2020 9:95
  46. Recognising the influence of context and the context-sensitive nature of quality improvement (QI) interventions is crucial to implementing effective improvements and successfully replicating them in new settin...

    Authors: Emma Coles, Julie Anderson, Margaret Maxwell, Fiona M. Harris, Nicola M. Gray, Gill Milner and Stephen MacGillivray
    Citation: Systematic Reviews 2020 9:94

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