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  1. With an ageing population, the incidence of hip fractures requiring surgery is increasing. Post-operative delirium is common following hip fracture surgery. Delirium is associated with high mortality and morbi...

    Authors: Joyce Yeung, Vanisha Patel, Rita Champaneria and Janine Dretzke

    Citation: Systematic Reviews 2016 5:66

    Content type: Protocol

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  2. There has been a global increase in the use of herbal medicinal products (HMPs). About a quarter of UK adults use HMPs, bought over the counter by self-prescription and often not disclosed to healthcare profes...

    Authors: Taofikat Agbabiaka, Barbara Wider, Leala Kay Watson and Claire Goodman

    Citation: Systematic Reviews 2016 5:65

    Content type: Protocol

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  3. In recent years, there have been numerous calls for global institutions to develop and enforce new international laws. International laws are, however, often blunt instruments with many uncertain benefits, cos...

    Authors: Steven J. Hoffman, Matthew Hughsam, Harkanwal Randhawa, Lathika Sritharan, Gordon Guyatt, John N. Lavis and John-Arne Røttingen

    Citation: Systematic Reviews 2016 5:64

    Content type: Protocol

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  4. People living with HIV (PLHIV) in African countries are living longer due to the rollout of antiretroviral drug therapy programs, but they are at increasing risk of non-communicable diseases (NCDs). However, t...

    Authors: David A. Watkins, Nathaniel L. Tulloch, Molly E. Anderson, Scott Barnhart, Krisela Steyn and Naomi S. Levitt

    Citation: Systematic Reviews 2016 5:63

    Content type: Protocol

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  5. Anticipatory (APAs) and compensatory (CPAs) postural adjustments are organised by the central nervous system (CNS) and serve to control postural perturbations. Ineffective APAs and CPAs have been hypothesised ...

    Authors: Michael F. Knox, Lucy S. Chipchase, Siobhan M. Schabrun and Paul W. M. Marshall

    Citation: Systematic Reviews 2016 5:62

    Content type: Protocol

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  6. Claims of and calls for evidence-informed policymaking pervade public health journals and the literature of governments and global health agencies, yet our knowledge of the arrangements most conducive to the a...

    Authors: Ben Verboom, Paul Montgomery and Sara Bennett

    Citation: Systematic Reviews 2016 5:61

    Content type: Protocol

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  7. Kawasaki disease (KD) is a form of self-limiting vasculitis that causes coronary artery abnormality in children. Based on reports of elevated plasma level of cytokines such as tumor necrosis factor-α in KD pat...

    Authors: Osamu Nomura, Sayaka Fukuda, Erika Ota, Hiroshi Ono, Akira Ishiguro and Tohru Kobayashi

    Citation: Systematic Reviews 2016 5:60

    Content type: Protocol

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  8. Information technologies can facilitate the implementation of health interventions, especially in the case of widespread conditions such as pain. Tailored Web-based interventions have been recognized for healt...

    Authors: Géraldine Martorella, C. Gélinas, M. Bérubé, M. Boitor, S. Fredericks and S. LeMay

    Citation: Systematic Reviews 2016 5:59

    Content type: Protocol

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  9. The welfare state is potentially an important macro-level determinant of health that also moderates the extent, and impact, of socio-economic inequalities in exposure to the social determinants of health. The ...

    Authors: Katie Thomson, Clare Bambra, Courtney McNamara, Tim Huijts and Adam Todd

    Citation: Systematic Reviews 2016 5:57

    Content type: Protocol

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  10. Vasomotor symptoms such as hot flashes and night sweats are a common concern of perimenopausal and postmenopausal women and are associated with a decreased quality of life. These symptoms can be effectively ma...

    Authors: Karen M. Goldstein, Jennifer R. McDuffie, Megan Shepherd-Banigan, Deanna Befus, Remy R. Coeytaux, Megan G. Van Noord, Adam P. Goode, Varsha Masilamani, Soheir Adam, Avishek Nagi and John W. Williams Jr

    Citation: Systematic Reviews 2016 5:56

    Content type: Protocol

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    The Erratum to this article has been published in Systematic Reviews 2016 5:69

  11. Out-of-hospital cardiac arrest (OHCA) is a significant cause of death in developed countries. The majority of OHCA patients are elderly (≥65 years), and it was documented that they were less likely than younge...

    Authors: Joanna M. Bielecki, Josephine Wong, Nicholas Mitsakakis, Prakesh S. Shah, Murray D. Krahn and Valeria E. Rac

    Citation: Systematic Reviews 2016 5:55

    Content type: Protocol

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  12. There is a growing emphasis in public health on the importance of evidence-based interventions to improve population health and reduce health inequities. Equally important is the need for knowledge about how t...

    Authors: Marjorie MacDonald, Bernadette Pauly, Geoff Wong, Kara Schick-Makaroff, Thea van Roode, Heather Wilson Strosher, Anita Kothari, Ruta Valaitis, Heather Manson, Warren O’Briain, Simon Carroll, Victoria Lee, Samantha Tong, Karen Dickenson Smith and Megan Ward

    Citation: Systematic Reviews 2016 5:54

    Content type: Protocol

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  13. Unregulated care aides provide up to 80 % of direct resident care in nursing homes. They have little formal training, manage high workloads, frequently experience responsive behaviours from residents, and are ...

    Authors: Matthias Hoben, Huimin Hu, Tianyuan Xiong, Angelle Kent, Nadia Kobagi and Minn N. Yoon

    Citation: Systematic Reviews 2016 5:53

    Content type: Protocol

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  14. HIV is still a global public health problem. More than 75 % of HIV-infected people are in Africa, and most of them are unaware of their HIV status, which is a barrier to accessing antiretroviral treatment. Our...

    Authors: Bernard Njau, Damian J. Damian, Leila Abdullahi, Andrew Boulle and Catherine Mathews

    Citation: Systematic Reviews 2016 5:52

    Content type: Protocol

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  15. Sleep disturbance is a common and significant health problem that has been linked to decreased quality of life. Mindfulness-based stress reduction (MBSR) can be a potentially effective intervention for insomni...

    Authors: Seong Min Kim, Jeong Min Park and Hyun-Ju Seo

    Citation: Systematic Reviews 2016 5:51

    Content type: Protocol

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  16. Most orthodontic mini-implants (OMIs) are inserted between dental roots. The prevalence of contacting these structures is high. Such contacts can cause permanent root damage and implant instability. Increased ...

    Authors: Reint Meursinge Reynders, Luisa Ladu, Laura Ronchi, Nicola Di Girolamo, Jan de Lange, Nia Roberts and Annette Plüddemann

    Citation: Systematic Reviews 2016 5:50

    Content type: Research

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  17. Research examining the effects of oxytocin (OT) interventions on psychiatric, social-behavioral, and social-cognitive outcomes regularly collect peripheral levels of OT as markers of central bioavailability. S...

    Authors: Mathias Valstad, Gail A. Alvares, Ole A. Andreassen, Lars T. Westlye and Daniel S. Quintana

    Citation: Systematic Reviews 2016 5:49

    Content type: Protocol

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  18. Blinding is a measure in randomized controlled trials (RCT) to reduce detection and performance bias. There is evidence that lack of blinding leads to overestimated treatment effects. Because of the physical c...

    Authors: Pascal Probst, Kathrin Grummich, Patrick Heger, Steffen Zaschke, Phillip Knebel, Alexis Ulrich, Markus W. Büchler and Markus K. Diener

    Citation: Systematic Reviews 2016 5:48

    Content type: Protocol

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  19. It is known that regular physical activity (PA) is associated with improvements in physical, psychological, cognitive, and functional health outcomes. The World Health Organization recommends 150 min of modera...

    Authors: Saskia Muellmann, Sarah Forberger, Tobias Möllers, Hajo Zeeb and Claudia R Pischke

    Citation: Systematic Reviews 2016 5:47

    Content type: Protocol

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  20. There is an increased need for additional care and support services for the elderly population. It is important to identify what support older people need once they are discharged from hospital and to ensure c...

    Authors: Elaine O’Connell Francischetto, Sarah Damery, Sarah Davies and Gill Combes

    Citation: Systematic Reviews 2016 5:46

    Content type: Protocol

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  21. Cerebral palsy (CP) is the most common, life-long paediatric disability. Taking care of a child with CP often results in caregiver burden/strain in the long run. As caregivers play an essential role in the reh...

    Authors: Jermaine M. Dambi, Jennifer Jelsma, Tecla Mlambo, Matthew Chiwaridzo, Nyaradzai Dangarembizi-Munambah and Lieselotte Corten

    Citation: Systematic Reviews 2016 5:42

    Content type: Protocol

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  22. There has been an expansion of circumcision services in Africa as part of a long-term HIV prevention strategy. However, the effect of infant male circumcision on morbidity and mortality still remains unclear. ...

    Authors: Thomas Gyan, Natalie Strobel, Kimberley McAuley, Caitlin Shannon, Sam Newton, Charlotte Tawiah-Agyemang, Seeba Amenga-Etego, Seth Owusu-Agyei, David Forbes and Karen Edmond

    Citation: Systematic Reviews 2016 5:41

    Content type: Protocol

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  23. Abstracts and plain language summaries (PLS) are often the first, and sometimes the only, point of contact between readers and systematic reviews. It is important to identify how these summaries are used and t...

    Authors: Fiona Alderdice, Jenny McNeill, Toby Lasserson, Elaine Beller, Margaret Carroll, Vanora Hundley, Judith Sunderland, Declan Devane, Jane Noyes, Susan Key, Sarah Norris, Janine Wyn-Davies and Mike Clarke

    Citation: Systematic Reviews 2016 5:40

    Content type: Research

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  24. Previously, we reported on the low recall of Google Scholar (GS) for systematic review (SR) searching. Here, we test our conclusions further in a prospective study by comparing the coverage, recall, and precis...

    Authors: Wichor M. Bramer, Dean Giustini and Bianca M. R. Kramer

    Citation: Systematic Reviews 2016 5:39

    Content type: Research

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  25. Liver resection is commonly performed for malignant and benign disease and is associated with frequent use of intraoperative and postoperative blood transfusions. Blood transfusions are potentially life-saving...

    Authors: Sean Bennett, Laura Baker, Risa Shorr, Guillaume Martel and Dean Fergusson

    Citation: Systematic Reviews 2016 5:38

    Content type: Protocol

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  26. Health information has become readily accessible through mass media, and people are playing a more active and autonomous role in their health. Much of the health information that was previously only available ...

    Authors: Leila Cusack, Chris B. Del Mar, Iain Chalmers and Tammy C. Hoffmann

    Citation: Systematic Reviews 2016 5:37

    Content type: Protocol

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  27. A peer-reviewed journal would not survive without the generous time and insightful comments of the reviewers, whose efforts often go unrecognized. Although final decisions are always editorial, they are greatl...

    Authors: David Moher, Paul Shekelle and Lesley A. Stewart

    Citation: Systematic Reviews 2016 5:36

    Content type: Reviewer acknowledgement

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  28. The spread of early detection and the improvement of cancer treatment have led to an increased prevalence of cancer survivors, including in the working age population. Return-to-work (RTW) of cancer survivors ...

    Authors: Régine Kiasuwa Mbengi, Renée Otter, Katrien Mortelmans, Marc Arbyn, Herman Van Oyen, Catherine Bouland and Christophe de Brouwer

    Citation: Systematic Reviews 2016 5:35

    Content type: Research

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  29. Some sedatives used in children and adolescents can affect memory function. Memory impairment of traumatic experience can minimize the chance of future psychological trauma. Knowledge about the potential of di...

    Authors: Karolline A. Viana, Anelise Daher, Lucianne C. Maia, Paulo S. Costa, Carolina C. Martins, Saul M. Paiva and Luciane R. Costa

    Citation: Systematic Reviews 2016 5:34

    Content type: Protocol

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  30. This letter describes a simple way of using Adobe Acrobat Pro DC to help select and auto-extract data from Portable Document Format (PDFs) of randomised trials in order to assist swift early selection of trial...

    Authors: Selin Nur, Clive E. Adams and David F. Brailsford

    Citation: Systematic Reviews 2016 5:33

    Content type: Letter

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  31. Physical performance such as muscle strength or walking speed of patients with coronary artery disease (CAD) is lower than that of people who do not have CAD and is related to mortality and re-admission rates....

    Authors: Shuhei Yamamoto, Takayoshi Yamaga, Yasunari Sakai, Takaaki Ishida, Saki Nakasone, Masayoshi Ohira, Erika Ota and Rintaro Mori

    Citation: Systematic Reviews 2016 5:32

    Content type: Protocol

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  32. In the UK, over 6500 people die by suicide each year. In England alone, this is one person every 2 h. Professionals assess risk of suicide in face-to-face contacts with people potentially at risk. The National...

    Authors: Rose McCabe, Ruth Garside, Amy Backhouse and Penny Xanthopoulou

    Citation: Systematic Reviews 2016 5:31

    Content type: Protocol

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  33. Despite progress in developing technologies for health promotion and disease treatment, mental disorders remain highly prevalent. In light of the associated personal and societal burden, primary prevention of ...

    Authors: Lasse Sander, Leonie Rausch and Harald Baumeister

    Citation: Systematic Reviews 2016 5:30

    Content type: Protocol

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    The Erratum to this article has been published in Systematic Reviews 2016 5:156

  34. Macular oedema (MO) describes the accumulation of fluid in the central part of the retina, known as the ‘macula’ which provides central vision. MO is the leading cause of sight loss in patients with intraocula...

    Authors: Mohammad O. Tallouzi, David J. Moore, Melanie Calvert, Philip I. Murray, Nicholas Bucknall and Alastair K. Denniston

    Citation: Systematic Reviews 2016 5:29

    Content type: Protocol

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  35. The need for systematic methods for reviewing evidence is continuously increasing. Evidence mapping is one emerging method. There are no authoritative recommendations for what constitutes an evidence map or wh...

    Authors: Isomi M. Miake-Lye, Susanne Hempel, Roberta Shanman and Paul G. Shekelle

    Citation: Systematic Reviews 2016 5:28

    Content type: Research

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  36. Bibliographic databases are the primary resource for identifying systematic reviews of health care interventions. Reliable retrieval of systematic reviews depends on the scope of indexing used by database prov...

    Authors: John Rathbone, Matt Carter, Tammy Hoffmann and Paul Glasziou

    Citation: Systematic Reviews 2016 5:27

    Content type: Research

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  37. Eczema is a common chronic or chronically relapsing, inflammatory skin disease that exerts a substantial negative impact on quality of life (QoL). The Harmonising Outcome Measures for Eczema (HOME) initiative ...

    Authors: Daniel Heinl, Cecilia A. C. Prinsen, Aaron M. Drucker, Robert Ofenloch, Rosemary Humphreys, Tracey Sach, Carsten Flohr and Christian Apfelbacher

    Citation: Systematic Reviews 2016 5:25

    Content type: Protocol

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  38. The length of postnatal hospital stay has declined over the last 40 years. There is little evidence to support a policy of early discharge following birth, and there is some concern about whether early dischar...

    Authors: Eleanor Jones, Beck Taylor, Christine MacArthur, Ruth Pritchett and Carole Cummins

    Citation: Systematic Reviews 2016 5:24

    Content type: Protocol

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  39. Of the over 1 million reported cases of traumatic brain injuries reported annually in the USA, a sizeable proportion are characterized as mild. Although it is generally well-accepted that most people who suffe...

    Authors: Chris Lepage, Tina Yuan, Stephanie Leon, Shawn Marshall, Patrick Labelle and Mark Ferland

    Citation: Systematic Reviews 2016 5:23

    Content type: Protocol

    Published on:

  40. Most orthodontic treatment plans need some form of anchorage to control the reciprocal forces of tooth movement. Orthodontic mini implants (OMIs) have been hailed for having revolutionized orthodontics, becaus...

    Authors: Reint Meursinge Reynders, Laura Ronchi, Luisa Ladu, Nicola Di Girolamo, Jan de Lange, Nia Roberts and Sharon Mickan

    Citation: Systematic Reviews 2016 5:22

    Content type: Protocol

    Published on:

  41. The prevalence of paternal depression in the postnatal period is estimated to be approximately 10 %. Effective partner education during pregnancy has the possibility to prevent postnatal mental health problems...

    Authors: Maiko Suto, Kenji Takehara, Yumina Yamane and Erika Ota

    Citation: Systematic Reviews 2016 5:21

    Content type: Protocol

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  42. The lack of evidence of the role of workplaces as settings for behaviour change delivery and the failure to recognise and address the complexity of the work environment has been acknowledged. This systematic r...

    Authors: Sarah A. Smith, Amelia A. Lake, Carolyn Summerbell, Vera Araujo-Soares and Frances Hillier-Brown

    Citation: Systematic Reviews 2016 5:20

    Content type: Protocol

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  43. Prosthetic hip implants have many combinations of bearing surface materials, sizes, and fixation techniques, which can determine the quality of life of patients after primary total hip replacement (THR) and th...

    Authors: Elsa M. R. Marques, Rachel Humphriss, Nicky J. Welton, Julian P. T. Higgins, William Hollingworth, Jose A. Lopez-Lopez, Howard Thom, Linda P. Hunt, Ashley W. Blom and Andrew D. Beswick

    Citation: Systematic Reviews 2016 5:19

    Content type: Protocol

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  44. Periodontal disease is an inflammatory disease of the tissues supporting the teeth. Women who have periodontal disease while pregnant may be at risk of adverse pregnancy outcomes. Although the association betw...

    Authors: Sizzle F. Vanterpool, Kathleen Tomsin, Leticia Reyes, Luc J. Zimmermann, Boris W. Kramer and Jasper V. Been

    Citation: Systematic Reviews 2016 5:16

    Content type: Protocol

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