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  1. Despite the growing interest in assessing the quality of care for depression, there is little evidence to support measurement of the quality of primary care for depression. This study identified evidence-based...

    Authors: Yelena Petrosyan, Yeva Sahakyan, Jan M. Barnsley, Kerry Kuluski, Barbara Liu and Walter P. Wodchis
    Citation: Systematic Reviews 2017 6:126
  2. Understanding how physical activity (PA) influences cognitive function in populations with cognitive impairments, such as dementia, is an increasingly studied topic yielding numerous published systematic revie...

    Authors: Azeem Rathore and Barbara Lom
    Citation: Systematic Reviews 2017 6:124
  3. Multiple reviews demonstrated high variability in effectiveness and cost-effectiveness outcomes among studies on breast cancer screening (BCS) programmes. No study to our knowledge has summarized the current e...

    Authors: O. Mandrik, O. I. Ekwunife, N. Zielonke, F. Meheus, J. L. Severens, S. K. Lhachimi and R. Murillo
    Citation: Systematic Reviews 2017 6:122
  4. Anxiety and depression are common in young people and are associated with a range of adverse outcomes. Research has suggested a relationship between emotional disorder and poor school attendance, and thus poor...

    Authors: Katie Finning, Darren Moore, Obioha C. Ukoumunne, Emilia Danielsson-Waters and Tamsin Ford
    Citation: Systematic Reviews 2017 6:121
  5. Cellular-based therapies represent a platform technology within the rapidly expanding field of regenerative medicine and are distinct from conventional therapeutics—offering a unique approach to managing what ...

    Authors: David Pettitt, Zeeshaan Arshad, Benjamin Davies, James Smith, Anna French, Doug Cole, Kim Bure, Sue Dopson, David DiGiusto, Jeff Karp, Brock Reeve, Richard Barker, Georg Holländer and David Brindley
    Citation: Systematic Reviews 2017 6:120
  6. Network meta-analysis, a method to synthesise evidence from multiple treatments, has increased in popularity in the past decade. Two broad approaches are available to synthesise data across networks, namely, a...

    Authors: Amalia (Emily) Karahalios, Georgia Salanti, Simon L. Turner, G. Peter Herbison, Ian R. White, Areti Angeliki Veroniki, Adriani Nikolakopoulou and Joanne E. Mckenzie
    Citation: Systematic Reviews 2017 6:119
  7. Stress ulcer prophylaxis is considered standard of care in many critically ill patients in the intensive care unit (ICU). However, the quality of evidence supporting this has recently been questioned, and clin...

    Authors: Søren Marker, Anders Perner, Jørn Wetterslev, Marija Barbateskovic, Janus Christian Jakobsen, Mette Krag, Anders Granholm, Carl Thomas Anthon and Morten Hylander Møller
    Citation: Systematic Reviews 2017 6:118
  8. The methodological quality and completeness of reporting of the systematic reviews (SRs) is fundamental to optimal implementation of evidence-based health care and the reduction of research waste. Methods exis...

    Authors: Kusala Pussegoda, Lucy Turner, Chantelle Garritty, Alain Mayhew, Becky Skidmore, Adrienne Stevens, Isabelle Boutron, Rafael Sarkis-Onofre, Lise M. Bjerre, Asbjørn Hróbjartsson, Douglas G. Altman and David Moher
    Citation: Systematic Reviews 2017 6:117
  9. Preliminary evidence suggests statins may reduce major perioperative vascular events. However, evidence is limited to observational studies, underpowered trials, and non-comprehensive systematic reviews. This ...

    Authors: Erica Aranha Suzumura, Rodrigo Antonini Ribeiro, Leticia Kawano-Dourado, Pedro Gabriel de Barros e Silva, Claudia Oliveira, Mabel Fernandes Figueiró, Alexandre Biasi Cavalcanti, Renato D. Lopes and Otavio Berwanger
    Citation: Systematic Reviews 2017 6:116
  10. The practicality of applying evidence to healthcare systems with the aim of implementing change is an ongoing challenge for practitioners, policy makers, and academics. Shared decision- making (SDM), a method ...

    Authors: Gary Groot, Tamara Waldron, Tracey Carr, Linda McMullen, Lori-Ann Bandura, Shelley-May Neufeld and Vicky Duncan
    Citation: Systematic Reviews 2017 6:114
  11. Hemodynamic instability during renal replacement therapy (HIRRT) in the form of intradialytic hypotension (IDH) is a frequent complication of hemodialysis in end-stage kidney disease (ESKD), and most studies h...

    Authors: Adrianna Douvris, Swapnil Hiremath, Lauralyn McIntyre, Lindsey Sikora, Catherine Weber and Edward G. Clark
    Citation: Systematic Reviews 2017 6:113
  12. Evidence highlights a high prevalence of common mental health disorders in armed forces veterans and their families, with depression, anxiety, alcohol misuse and anger being more common than PTSD. This paper p...

    Authors: Luke O’Shea, Ed Watkins and Paul Farrand
    Citation: Systematic Reviews 2017 6:112
  13. The use of fat grafting as a reconstructive surgical option is becoming much more common. Adipose-derived stem cells found in fat grafts are believed to facilitate wound healing via differentiation into fibrob...

    Authors: Oliver J. Smith, Muholan Kanapathy, Ankur Khajuria, Max Prokopenko, Nadine Hachach-Haram, Haroon Mann and Ash Mosahebi
    Citation: Systematic Reviews 2017 6:111
  14. There exist many evidence-based interventions available to manage procedural pain in children and neonates, yet they are severely underutilized. Parents play an important role in the management of their child’...

    Authors: Allison Gates, Kassi Shave, Robin Featherstone, Kelli Buckreus, Samina Ali, Shannon Scott and Lisa Hartling
    Citation: Systematic Reviews 2017 6:109
  15. Achilles tendinopathy is one of the most common overuse injuries in recreational and competitive runners, yet the clinical significance and frequency of abnormal sonographic characteristics in runners remains ...

    Authors: Prue Molyneux, Matthew Carroll, Sarah Stewart, Angela Brenton-Rule and Keith Rome
    Citation: Systematic Reviews 2017 6:108
  16. It is not known, whether outcome reporting in trials of total joint arthroplasty in the recent years is adequate or not. Our objective was to assess whether outcomes reported in total joint replacement (TJR) t...

    Authors: Peter D. H. Wall, Bethan L. Richards, Andrew Sprowson, Rachelle Buchbinder and Jasvinder A. Singh
    Citation: Systematic Reviews 2017 6:106
  17. Debates about the benefits and harms of mammography continue despite the accumulation of evidence. We sought to quantify the disagreement across systematic reviews of mammography and determine whether author o...

    Authors: Smriti Raichand, Adam G. Dunn, Mei-Sing Ong, Florence T. Bourgeois, Enrico Coiera and Kenneth D. Mandl
    Citation: Systematic Reviews 2017 6:105
  18. Polypharmacy, the concurrent use of multiple medications, consistently evokes a negative connotation, notably because it is associated with a plethora of adverse events. Nonetheless, the number of individuals ...

    Authors: Caroline Sirois, Marie-Laure Laroche, Line Guénette, Edeltraut Kröger, Dan Cooper and Valérie Émond
    Citation: Systematic Reviews 2017 6:104
  19. Ventilator-associated pneumonia (VAP) is defined as the occurrence of pneumonia in patients receiving mechanical ventilation for more than 48 h after endotracheal intubation. The implementation of effective or...

    Authors: Zhigang Zhang, Yuying Hou, Jun Zhang, Bo Wang, Juxia Zhang, Ailing Yang, Ge Li and Jinhui Tian
    Citation: Systematic Reviews 2017 6:103
  20. Cardiorespiratory fitness (CRF) is a physical condition that is now well established as a predictor of numerous adverse health outcomes, independent of physical activity levels. In order to be able to improve ...

    Authors: Nita Perumal, Gert B.M. Mensink, Thomas Keil and Jonas David Finger
    Citation: Systematic Reviews 2017 6:102
  21. Diabetic foot disease is associated with major morbidity, mortality, costs, and reduction of a person’s quality of life. Investigating the epidemiology of diabetic foot disease is the backbone of diabetic foot...

    Authors: Jaap J. van Netten, Mendel Baba and Peter A. Lazzarini
    Citation: Systematic Reviews 2017 6:101
  22. With an ageing population and increasing numbers of people with life-limiting illness, there is a growing demand for palliative day services. There is a need to measure and demonstrate the quality of these ser...

    Authors: Seán R. O’Connor, Martin Dempster and Noleen K. McCorry
    Citation: Systematic Reviews 2017 6:100
  23. Parkinson’s disease (PD) is a progressive neurodegenerative condition that has genetic susceptibility, aging, and exposure to certain chemicals as risk factors. In recent decades, epidemiological and experimen...

    Authors: Carolina Vaccari, Regina El Dib and João Lauro V. de Camargo
    Citation: Systematic Reviews 2017 6:98
  24. Fibromyalgia (FM) is a chronic, debilitating pain disorder. Dissatisfaction with conventional medicine can lead people with FM to turn to complementary and alternative medicine (CAM). Two previous overviews of...

    Authors: Rachel Perry, Verity Leach, Philippa Davies, Chris Penfold, Andy Ness and Rachel Churchill
    Citation: Systematic Reviews 2017 6:97
  25. Hyperglycaemia-induced oxidative damage is a well-established factor implicated in the development of diabetic cardiomyopathy (DCM) in diabetic individuals. Some of the well-known characteristics of DCM includ...

    Authors: Phiwayinkosi V. Dludla, Bongani B. Nkambule, Stephanie C. Dias and Rabia Johnson
    Citation: Systematic Reviews 2017 6:96
  26. Short and poor sleep have been associated with adverse health outcomes in adults, such as overweight/obesity and type 2 diabetes, especially among women. Women therefore represent an important target for inter...

    Authors: Lydi-Anne Vézina-Im, Jennette Palcic Moreno, Theresa A. Nicklas and Tom Baranowski
    Citation: Systematic Reviews 2017 6:95
  27. Clinical supervision by a senior therapist is a very common practice in psychotherapist training and psychiatric care settings. Though clinical supervision is advocated by most educational and governing instit...

    Authors: Sven Alfonsson, Åsa Spännargård, Thomas Parling, Gerhard Andersson and Tobias Lundgren
    Citation: Systematic Reviews 2017 6:94
  28. Knowledge translation (KT) activities can reduce the gap between “what is known” and “what is done”. Several factors hinder or facilitate KT activities including individual characteristics and organizational a...

    Authors: Anastasia A. Mallidou, Pat Atherton, Liza Chan, Noreen Frisch, Stephanie Glegg and Gayle Scarrow
    Citation: Systematic Reviews 2017 6:93
  29. Elective knee surgery is performed to reduce chronic pain and improve function in degenerate knees. Treatment of acute post-operative pain is suboptimal in 75% of patients despite multimodal analgesic approach...

    Authors: Hasan Raza Mohammad, Marialena Trivella, Thomas W. Hamilton, Louise Strickland, David Murray and Hemant Pandit
    Citation: Systematic Reviews 2017 6:92
  30. Over 85% of cervical cancer cases and deaths occur in developing countries. HIV-seropositive women are more likely to develop precancerous lesions that lead to cervical cancer than HIV-negative women. However,...

    Authors: Witness Mapanga, Ahmed Elhakeem, Shingairai A. Feresu, Fresier Maseko and Tsungai Chipato
    Citation: Systematic Reviews 2017 6:91
  31. Guidelines and evidence-based drug treatment recommendations are usually based on the results of clinical trials, which have limited generalisability in routine clinical settings due to their restrictive eligi...

    Authors: Weyinmi A. Demeyin, Julia Frost, Obioha C. Ukoumunne, Simon Briscoe and Nicky Britten
    Citation: Systematic Reviews 2017 6:90
  32. Endovascular interventional radiology (EIR) is an increasingly popular, mini invasive treatment option for patient with symptomatic vascular disease. The EIR practiced by qualified hands is an effective, well-...

    Authors: Kaoutar Mellouk Aid, Hervé Tchala Vignon Zomahoun, Abdelmajid Soulaymani, Karin Lebascle, Stephane Silvera, Pascal Astagneau and Benoit Misset
    Citation: Systematic Reviews 2017 6:89
  33. Prognosis research is on the rise, its importance recognised because chronic health conditions and diseases are increasingly common and costly. Prognosis systematic reviews are needed to collate and synthesise...

    Authors: Nadia Corp, Joanne L. Jordan, Jill A. Hayden, Emma Irvin, Robin Parker, Andrea Smith and Danielle A. van der Windt
    Citation: Systematic Reviews 2017 6:88
  34. Gaucher disease (GD) is an autosomal recessive lysosomal storage disorder caused by deficiency in acid beta-glucosidase. GD exhibits a wide clinical spectrum of disease severity with an unpredictable natural c...

    Authors: Tatiana Raskovalova, Patrick B. Deegan, Ruby Yang, Elena Pavlova, Jérome Stirnemann, José Labarère, Ari Zimran, Pramod K. Mistry and Marc Berger
    Citation: Systematic Reviews 2017 6:87
  35. The objective of this review was to update a systematic review of associations between living near an animal feeding operation (AFO) and human health.

    Authors: Annette M. O’Connor, Brent W. Auvermann, Rungano S. Dzikamunhenga, Julie M. Glanville, Julian P. T. Higgins, Shelley P. Kirychuk, Jan M. Sargeant, Sarah C. Totton, Hannah Wood and Susanna G. Von Essen
    Citation: Systematic Reviews 2017 6:86
  36. Experiencing mental ill health adds a layer of complexity for individuals in touch with the justice system and for those responsible for working in the justice service with these individuals, such as frontline...

    Authors: Eddie Kane, Emily Evans and Farhad Shokraneh
    Citation: Systematic Reviews 2017 6:85
  37. Approximately 5 to 10% of critically ill patients transition from acute critical illness to a state of persistent and in some cases chronic critical illness. These patients have unique and complex needs that r...

    Authors: Louise Rose, Laura Istanboulian, Laura Allum, Lisa Burry, Craig Dale, Nicholas Hart, Claire Kydonaki, Pam Ramsay, Natalie Pattison and Bronwen Connolly
    Citation: Systematic Reviews 2017 6:84
  38. Learning activities are fundamental for the development of expertise in physiotherapy practice. Continuing professional development (CPD) encompasses formal and informal learning activities undertaken by physi...

    Authors: Edmund Leahy, Lucy Chipchase and Felicity Blackstock
    Citation: Systematic Reviews 2017 6:83
  39. Cochrane primarily aims to systematically review trials of effectiveness that are important to inform clinical decisions. Editorial groups support authors to achieve high-quality reviews and prioritise review ...

    Authors: Jasmin Alloo, Sanya Vallath, Chris Del Mar, Matt Carter, Sarah Thorning and Justin Clark
    Citation: Systematic Reviews 2017 6:82
  40. Spitz nevi are uncommon melanocytic neoplasms found in children. Historically, the diagnosis and management of these tumors has lacked consensus among oncologists, pathologists, plastic surgeons, and dermatolo...

    Authors: Jean Abboud, Michael Stein, Michele Ramien and Claudia Malic
    Citation: Systematic Reviews 2017 6:81
  41. Hemorrhage is a major cause of early mortality following a traumatic injury. The progression and consequences of significant blood loss occur quickly as death from hemorrhagic shock or exsanguination often occ...

    Authors: Alexandre Tran, Maher Matar, Ewout W. Steyerberg, Jacinthe Lampron, Monica Taljaard and Christian Vaillancourt
    Citation: Systematic Reviews 2017 6:80
  42. When randomized trials have addressed multiple interventions for the same health problem, network meta-analyses (NMAs) permit researchers to statistically pool data from individual studies including evidence f...

    Authors: L. Mbuagbaw, B. Rochwerg, R. Jaeschke, D. Heels-Andsell, W. Alhazzani, L. Thabane and Gordon H. Guyatt
    Citation: Systematic Reviews 2017 6:79
  43. Previous studies investigating the mental health of migrants have shown mixed results. The increased availability of register data has led to a growing number of register-based studies in this research area. T...

    Authors: Kishan Patel, Anne Kouvonen, Ciara Close, Ari Väänänen, Dermot O’Reilly and Michael Donnelly
    Citation: Systematic Reviews 2017 6:78
  44. Alcohol dependence is common and serious cause of social and physical harm. However, the optimal management of those with moderate and severe alcohol dependence in primary and community care after detoxificati...

    Authors: Hung-Yuan Cheng, Roy G. Elbers, Julian P. T. Higgins, Abigail Taylor, Georgina J. MacArthur, Luke McGuinness, Sarah Dawson, José A. López-López, Sean Cowlishaw, Matthew Hickman and David Kessler
    Citation: Systematic Reviews 2017 6:77
  45. Alcohol use is the behaviour that has the most significant impact on the mortality and morbidity of young people, and binge drinking is becoming the norm among this population. The burden of disease of binge d...

    Authors: Jennifer Hasselgård-Rowe, Barbara Broers and Dagmar M. Haller
    Citation: Systematic Reviews 2017 6:76

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