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  1. Content type: Reviewer acknowledgement

    A peer-reviewed journal would not survive without the generous time and insightful comments of the reviewers, whose efforts often go unrecognized. Systematic Reviews has been blessed by the support of highly-qual...

    Authors: Daniel Shanahan

    Citation: Systematic Reviews 2014 3:6

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  2. Content type: Protocol

    Advances in surgical technique, prosthetic heart valve design, and anticoagulation have contributed to an overall improvement in morbidity and mortality in women with heart valve prostheses as well as increase...

    Authors: Claire M Lawley, Samantha J Lain, Charles S Algert, Jane B Ford, Gemma A Figtree and Christine L Roberts

    Citation: Systematic Reviews 2014 3:8

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  3. Content type: Protocol

    Globally, the incidence of sexually transmitted infections (STI) is rising, posing a challenge to its control and appropriate management. Text messaging has become the most common mode of communication among a...

    Authors: Carole Lunny, Darlene Taylor, Jasmina Memetovic, Orion Wärje, Richard Lester, Tom Wong, Kendall Ho, Mark Gilbert and Gina Ogilvie

    Citation: Systematic Reviews 2014 3:7

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  4. Content type: Protocol

    Depression is common in people with long term conditions (LTCs) and is associated with worse medical outcomes. Understanding the mechanisms underpinning this relationship could help predict who is at increased...

    Authors: Leanne Trick, Edward Watkins and Chris Dickens

    Citation: Systematic Reviews 2014 3:5

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  5. Content type: Protocol

    Improving and sustaining the quality of care in hospitals is an intractable and persistent challenge. The patients’ experience of the quality of hospital care can provide insightful feedback to enable clinical...

    Authors: Michelle Beattie, William Lauder, Iain Atherton and Douglas J Murphy

    Citation: Systematic Reviews 2014 3:4

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  6. Content type: Protocol

    Although health care providers utilize classically described signs and symptoms to diagnose tension pneumothorax, available literature sources differ in their descriptions of its clinical manifestations. Moreo...

    Authors: Derek J Roberts, Simon Leigh-Smith, Peter D Faris, Chad G Ball, Helen Lee Robertson, Christopher Blackmore, Elijah Dixon, Andrew W Kirkpatrick, John B Kortbeek and Henry Thomas Stelfox

    Citation: Systematic Reviews 2014 3:3

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  7. Content type: Protocol

    Almost all patients under general anesthesia for surgery need mechanical ventilation. The harmful effects of short-term intra-operative ventilation on pulmonary integrity are increasingly recognized. Recent in...

    Authors: Ary Serpa Neto, Sabrine NT Hemmes, Marcelo Gama de Abreu, Paolo Pelosi and Marcus J Schultz

    Citation: Systematic Reviews 2014 3:2

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  8. Content type: Research

    Consensus has not been reached on safe alcohol consumption recommendations during pregnancy. The National Institutes for Care and Health Excellence (NICE) in the UK suggest that one to two drinks not more than...

    Authors: Linda M O’Keeffe, Richard A Greene and Patricia M Kearney

    Citation: Systematic Reviews 2014 3:1

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  9. Content type: Research

    Individuals with major psychotic and/or affective disorders are at increased risk for developing metabolic syndrome due to lifestyle- and treatment-related factors. Numerous pharmacological and non-pharmacolog...

    Authors: Cynthia Nover and Sarah S Jackson

    Citation: Systematic Reviews 2013 2:116

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  10. Content type: Methodology

    The usefulness of Google Scholar (GS) as a bibliographic database for biomedical systematic review (SR) searching is a subject of current interest and debate in research circles. Recent research has suggested ...

    Authors: Wichor M Bramer, Dean Giustini, Bianca MR Kramer and PF Anderson

    Citation: Systematic Reviews 2013 2:115

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  11. Content type: Protocol

    Previous studies have been limited in reporting the association between chocolate consumption, measured by interviewer-administered questionnaire or serum theobromine, a biomarker for cocoa, and risk of preecl...

    Authors: Jaime Andres Mogollon, Catherine Boivin, Kadhel Philippe, Stéphane Turcotte, Simone Lemieux, Claudine Blanchet, Emmanuel Bujold and Sylvie Dodin

    Citation: Systematic Reviews 2013 2:114

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  12. Content type: Protocol

    Clinicians, providers and guideline panels use absolute effects to weigh the advantages and downsides of treatment alternatives. Relative measures have the potential to mislead readers. However, little is know...

    Authors: Pablo Alonso-Coello, Alonso Carrasco-Labra, Romina Brignardello-Petersen, Ignacio Neumann, Elie A Akl, Xin Sun, Bradley C Johnston, Matthias Briel, Jason W Busse, Demián Glujovsky, Carlos E Granados, Alfonso Iorio, Affan Irfan, Laura M García, Reem A Mustafa, Anggie Ramirez-Morera…

    Citation: Systematic Reviews 2013 2:113

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    The Erratum to this article has been published in Systematic Reviews 2014 3:76

  13. Content type: Protocol

    Reports from Africa have suggested that pneumocystis pneumonia (PCP) is a less important cause of morbidity than in the developed world. However, more recent studies have shown high seroprevalence rates of P. jir...

    Authors: Sean Wasserman, Mark E Engel and Marc Mendelson

    Citation: Systematic Reviews 2013 2:112

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  14. Content type: Letter

    PROSPERO is an international database of prospectively registered systematic reviews in health and social care. Between July 2012 and June 2013, 1,106 registrations were added, bringing the total since launch ...

    Authors: Alison Booth

    Citation: Systematic Reviews 2013 2:111

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  15. Content type: Research

    Although it is often performed in clinical practice, the diagnostic value of a screening physical examination to detect maltreatment in children without prior suspicion has not been reviewed. This article aims...

    Authors: Eva MM Hoytema van Konijnenburg, Arianne H Teeuw, Tessa Sieswerda-Hoogendoorn, Arnold G E Leenders and Johanna H van der Lee

    Citation: Systematic Reviews 2013 2:109

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  16. Content type: Protocol

    Permanent childhood hearing loss affects 1 to 3 per 1000 children and frequently disrupts typical spoken language acquisition. Early identification of hearing loss through universal newborn hearing screening a...

    Authors: Elizabeth M Fitzpatrick, Adrienne Stevens, Chantelle Garritty and David Moher

    Citation: Systematic Reviews 2013 2:108

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  17. Content type: Methodology

    There are both theoretical and empirical reasons to believe that design and execution factors are associated with bias in controlled trials. Statistically significant moderator effects, such as the effect of t...

    Authors: Susanne Hempel, Jeremy NV Miles, Marika J Booth, Zhen Wang, Sally C Morton and Paul G Shekelle

    Citation: Systematic Reviews 2013 2:107

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  18. Content type: Commentary

    The Statistical Methods Group has played a pivotal role in The Cochrane Collaboration over the past 20 years. The Statistical Methods Group has determined the direction of statistical methods used within Cochr...

    Authors: Joanne E McKenzie, Georgia Salanti, Steff C Lewis and Douglas G Altman

    Citation: Systematic Reviews 2013 2:80

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  19. Content type: Protocol

    Virtually all low- and middle-income countries are dependent on the World Health Organization’s Expanded Program on Immunization for delivery of vaccines to children. The Expanded Program on Immunization deliv...

    Authors: Shingai Machingaidze, Eva Rehfuess, Rüdiger von Kries, Gregory D Hussey and Charles S Wiysonge

    Citation: Systematic Reviews 2013 2:106

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  20. Content type: Protocol

    Depression is common in people with chronic physical illness and is associated with worse medical outcomes. Cognitive behavioural therapy and problem-solving improve depression, although usually have small to ...

    Authors: Sarah Harris, Paul Farrand and Chris Dickens

    Citation: Systematic Reviews 2013 2:105

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  21. Content type: Methodology

    Systematic reviews (SRs) can become outdated as new evidence emerges over time. Organizations that produce SRs need a surveillance method to determine when reviews are likely to require updating. This report d...

    Authors: Nadera Ahmadzai, Sydne J Newberry, Margaret A Maglione, Alexander Tsertsvadze, Mohammed T Ansari, Susanne Hempel, Aneesa Motala, Sophia Tsouros, Jennifer J Schneider Chafen, Roberta Shanman, David Moher and Paul G Shekelle

    Citation: Systematic Reviews 2013 2:104

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  22. Content type: Protocol

    Dapagliflozin is a first-in-class oral sodium glucose co-transporter 2 (SGLT2) inhibitor. It is often used in combination with conventional anti-diabetic drugs such as metformin, glimepiride, and insulin in tr...

    Authors: Yu-nan Sun, Yi Zhou, Xi Chen, Wen-si Che and Siu-wai Leung

    Citation: Systematic Reviews 2013 2:103

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  23. Content type: Protocol

    Although healthcare administrative data are commonly used for traumatic brain injury research, there is currently no consensus or consistency on using the International Classification of Diseases version 10 co...

    Authors: Vincy Chan, Pravheen Thurairajah and Angela Colantonio

    Citation: Systematic Reviews 2013 2:102

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  24. Content type: Protocol

    Healthcare worker hand hygiene is thought to be one of the most important strategies to prevent healthcare-associated infections, but compliance is generally poor. Hand hygiene improvement interventions must i...

    Authors: Jocelyn A Srigley, David Lightfoot, Geoff Fernie, Michael Gardam and Matthew P Muller

    Citation: Systematic Reviews 2013 2:101

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  25. Content type: Protocol

    The essential clinical diagnostic components of brain death must include evidence for an established etiology capable of causing brain death, two independent clinical confirmations of the absence of all brains...

    Authors: Michaël Chassé, Peter Glen, Mary-Anne Doyle, Lauralyn McIntyre, Shane W English, Greg Knoll, Jean-François Lizé, Sam D Shemie, Claudio Martin, Alexis F Turgeon, François Lauzier and Dean A Fergusson

    Citation: Systematic Reviews 2013 2:100

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  26. Content type: Protocol

    Somatoform-type disorders and functional medically unexplained symptoms are extremely common in primary care settings. These disorders, however, are consistently underdiagnosed and under-recognised which precl...

    Authors: Alexandra M Murray, Anne Toussaint, Astrid Althaus and Bernd Löwe

    Citation: Systematic Reviews 2013 2:99

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  27. Content type: Protocol

    Accountability has center stage in the current post-Millennium Development Goals (MDG) debate. One of the effective strategies for building equitable health systems and providing quality health services is the...

    Authors: Elsbet Lodenstein, Marjolein Dieleman, Barend Gerretsen and Jacqueline EW Broerse

    Citation: Systematic Reviews 2013 2:98

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  28. Content type: Methodology

    Google Translate offers free Web-based translation, but it is unknown whether its translation accuracy is sufficient to use in systematic reviews to mitigate concerns about language bias.

    Authors: Ethan M Balk, Mei Chung, Minghua L Chen, Lina Kong Win Chang and Thomas A Trikalinos

    Citation: Systematic Reviews 2013 2:97

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  29. Content type: Protocol

    The prognostic accuracy of 1H (proton) magnetic resonance spectroscopy (MRS) in neonatal hypoxic-ischemic encephalopathy has been assessed by a criticized study-based meta-analysis. An individual patient data met...

    Authors: Pieter LJ Degraeuwe, Gerald J Jaspers, Nicola J Robertson and Alfons GH Kessels

    Citation: Systematic Reviews 2013 2:96

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  30. Content type: Research

    There is considerable unexplained heterogeneity in previous meta-analyses of randomized controlled trials (RCTs) evaluating the effects of patient decision aids on the accuracy of knowledge of outcome probabil...

    Authors: Stephen J Gentles, Dawn Stacey, Carol Bennett, Mohamad Alshurafa and Stephen D Walter

    Citation: Systematic Reviews 2013 2:95

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  31. Content type: Commentary

    Cochrane systematic reviews have proven to be beneficial for decision making processes, both on a practitioner and a policy level, and there are current initiatives to extend the types of evidence used by them...

    Authors: Karin Hannes, Andrew Booth, Janet Harris and Jane Noyes

    Citation: Systematic Reviews 2013 2:84

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  32. Content type: Research

    Post-marketing surveillance (PMS) may identify rare serious incidents or adverse events due to the long-term use of a medical device, which was not captured in the pre-market process. Percutaneous transluminal...

    Authors: Julie Polisena, Alan J Forster, Karen Cimon and Danielle Rabb

    Citation: Systematic Reviews 2013 2:94

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  33. Content type: Protocol

    Three meta-analyses and one systematic review have been conducted on the question of whether self-collected specimens are as accurate as clinician-collected specimens for STI screening. However, these reviews ...

    Authors: Darlene Taylor, Carole Lunny, Tom Wong, Mark Gilbert, Neville Li, Richard Lester, Mel Krajden, Linda Hoang and Gina Ogilvie

    Citation: Systematic Reviews 2013 2:93

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  34. Content type: Protocol

    Pediatric osteomyelitis is a bacterial infection of bones requiring prolonged antibiotic treatment using parenteral followed by enteral agents. Major complications of pediatric osteomyelitis include transition...

    Authors: Chelsey Grimbly, Jeff Odenbach, Ben Vandermeer, Sarah Forgie and Sarah Curtis

    Citation: Systematic Reviews 2013 2:92

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  35. Content type: Research

    In 1996, shortly after the founding of The Cochrane Collaboration, leading figures in test evaluation research established a Methods Group to focus on the relatively new and rapidly evolving methods for the sy...

    Authors: Mariska MG Leeflang, Jonathan J Deeks, Yemisi Takwoingi and Petra Macaskill

    Citation: Systematic Reviews 2013 2:82

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  36. Content type: Protocol

    Venous thromboembolism (VTE) is a chronic disease, with fatal recurrences occurring in 5% to 9% of patients, yet it is also one of the best examples of preventable disease. Prognostic models that utilise multi...

    Authors: Joie Ensor, Richard D Riley, David Moore, Susan Bayliss, Sue Jowett and David A Fitzmaurice

    Citation: Systematic Reviews 2013 2:91

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  37. Content type: Protocol

    The use of procedural sedation outside the operating theatre has increased in hospital settings and has gained popularity among non-anesthesiologists. Sedative agents used for procedural pain, although effecti...

    Authors: Siobhán McCoy, Abel Wakai, Carol Blackburn, Michael Barrett, Adrian Murphy, Maria Brenner, Philip Larkin, Gloria Crispino-O’Connell, Savithiri Ratnapalan and Ronan O’Sullivan

    Citation: Systematic Reviews 2013 2:89

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  38. Content type: Protocol

    Numerous tools and items have been developed in all health areas to assess the risk of bias of randomized controlled trials (RCTs). The Cochrane Collaboration (CC) released a new tool to assess bias in RCTs, b...

    Authors: Susan Armijo-Olivo, Jorge Fuentes, Todd Rogers, Lisa Hartling, Humam Saltaji and Greta G Cummings

    Citation: Systematic Reviews 2013 2:88

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  39. Content type: Protocol

    Multimorbidity is increasingly prevalent but, aside from epidemiological work, the impact on associated provision of healthcare and/or education is little understood. For example, it is unclear how or why heal...

    Authors: Sarah Yardley, Elizabeth Cottrell and Joanne Protheroe

    Citation: Systematic Reviews 2013 2:87

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  40. Content type: Protocol

    The concept of lung sounds conveying information regarding lung physiology has been used extensively in clinical practice, particularly with physical auscultation using a stethoscope. Advances in computer tech...

    Authors: Marc P Berry, Luigi Camporota and George Ntoumenopoulos

    Citation: Systematic Reviews 2013 2:86

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  41. Content type: Commentary

    The Cochrane Collaboration was established in 1993, following the opening of the UK Cochrane Centre in 1992, at a time when searching for studies for inclusion in systematic reviews was not well-developed. Rev...

    Authors: Carol Lefebvre, Julie Glanville, L Susan Wieland, Bernadette Coles and Alison L Weightman

    Citation: Systematic Reviews 2013 2:78

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  42. Content type: Protocol

    Racism is increasingly recognized as a key determinant of health. A growing body of epidemiological evidence shows strong associations between self-reported racism and poor health outcomes across diverse minor...

    Authors: Yin Paradies, Naomi Priest, Jehonathan Ben, Mandy Truong, Arpana Gupta, Alex Pieterse, Margaret Kelaher and Gilbert Gee

    Citation: Systematic Reviews 2013 2:85

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  43. Content type: Commentary

    Cochrane Reviews are intended to help providers, practitioners and patients make informed decisions about health care. The goal of the Cochrane Applicability and Recommendation Methods Group (ARMG) is to devel...

    Authors: Miranda W Langendam, Elie A Akl, Philipp Dahm, Paul Glasziou, Gordon Guyatt and Holger J Schünemann

    Citation: Systematic Reviews 2013 2:81

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  44. Content type: Methodology

    Methods for systematic reviews of the effects of health interventions have focused mainly on addressing the question of 'What works?’ or 'Is this intervention effective in achieving one or more specific outcom...

    Authors: Ian Shemilt, David McDaid, Kevin Marsh, Catherine Henderson, Evelina Bertranou, Jacqueline Mallander, Mike Drummond, Miranda Mugford and Luke Vale

    Citation: Systematic Reviews 2013 2:83

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  45. Content type: Protocol

    Effective interventions to improve quality of life of cancer survivors are essential. Numerous randomized controlled trials have evaluated the effects of physical activity or psychosocial interventions on heal...

    Authors: Laurien M Buffart, Joeri Kalter, Mai JM Chinapaw, Martijn W Heymans, Neil K Aaronson, Kerry S Courneya, Paul B Jacobsen, Robert U Newton, Irma M Verdonck-de Leeuw and Johannes Brug

    Citation: Systematic Reviews 2013 2:75

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