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Table 2 The relationship between TAT and the outcome of ischemic stroke patients after a follow-up

From: Effect of plasma thrombin-antithrombin complex on ischemic stroke: a systematic review and meta-analysis

Studies

Patients

Country

Cases

Average age

From the first onset to hospital

Cut-off of TAT

Follow-up time

Recurrence cases

Outcomes

OR

95CI

Test method

Takano K 1991 [17]

Acute cardioembolic stroke

Japan

22

64.7

Within 24 h

12.1 ng/mL

2 months

8

Recurrence

–

–

ELISA

E A Fon 1994 [24]

Transient ischemic attack (TIA)

Canada

36

68.8

Within 7 day

7.8 ng/mL

13 months

12

Recurrence

–

–

ELISA

Haapaniemi E. 2004 [27]

Ischemic stroke

Finland

55

60.2

Within 24 h

7.9 ng/L

3 years

16

Recurrence

–

–

ELISA

David Tanne 2006 [25]

Acute ischemic stroke

USA

361

68.0

Within 24 h

11.2 ng/mL

3 months

–

Mortality

1.72

1.26–2.34

EIA

Ye Naifang 2020 [23]

Acute ischemic stroke

China

236

70.0

Within 24 h

6.03 ng/mL

1 months

35

Unfavorable function

1.283

1.105–1.489

Chemilumi-nescence

Israel Fernandez-Cadenas 2009 [26]

Ischemic stroke

Spanish

89

72.4

Within 3 h

< 24 ÎĽg/L

3 months

16

Revascularis-ation rates

2.7

1.2–6.1

ELISA

  1. ELISA enzyme-linked immunosorbent assay, EIA enzyme immunoassays