Studies | Patients | Country | Cases | Average age | From the first onset to hospital | Cut-off of TAT | Follow-up time | Recurrence cases | Outcomes | OR | 95CI | Test method |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Takano K 1991 [17] | Acute cardioembolic stroke | Japan | 22 | 64.7 | Within 24 h | 12.1 ng/mL | 2 months | 8 | Recurrence | – | – | ELISA |
E A Fon 1994 [24] | Transient ischemic attack (TIA) | Canada | 36 | 68.8 | Within 7 day | 7.8 ng/mL | 13 months | 12 | Recurrence | – | – | ELISA |
Haapaniemi E. 2004 [27] | Ischemic stroke | Finland | 55 | 60.2 | Within 24 h | 7.9 ng/L | 3 years | 16 | Recurrence | – | – | ELISA |
David Tanne 2006 [25] | Acute ischemic stroke | USA | 361 | 68.0 | Within 24 h | 11.2 ng/mL | 3 months | – | Mortality | 1.72 | 1.26–2.34 | EIA |
Ye Naifang 2020 [23] | Acute ischemic stroke | China | 236 | 70.0 | Within 24 h | 6.03 ng/mL | 1 months | 35 | Unfavorable function | 1.283 | 1.105–1.489 | Chemilumi-nescence |
Israel Fernandez-Cadenas 2009 [26] | Ischemic stroke | Spanish | 89 | 72.4 | Within 3 h | < 24 μg/L | 3 months | 16 | Revascularis-ation rates | 2.7 | 1.2–6.1 | ELISA |