Table 2 Pooled estimates of autoantibodies
Autoantibody | Sensitivity (95% CI) | Specificity (95% CI) | Diagnostic odds ratio (95% CI) |
|---|---|---|---|
P53 | 0.184 (0.093–0.332) | 0.962 (0.912–0.984) | 5.760 (4.029–8.220) |
MUC1 | 0.498 (0.209–0.789) | 0.691 (0.257–0.935) | 2.215 (0.440–11.143) |
HER2 | 0.453 (0.064–0.910) | 0.794 (0.294–0.973) | 3.200 (1.700–6.025) |
HSP60 | 0.558 (0.210–0.857) | 0.802 (0.316–0.973) | 5.122 (2.145–12.229) |
P16 | 0.216 (0.142–0.314) | 0.941 (0.878–0.972) | 4.373 (2.329–8.209) |
Cyclin B1 | 0.149 (0.105–0.207) | 0.977 (0.946–0.990) | 7.455 (2.816–19.733) |
c-Myc | 0.103 (0.060–0.172) | 0.966 (0.919–0.986) | 3.230 (1.071–9.740) |