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Table 1 Summary of physical exam maneuvers and outcomes of the included studies organized by physical exam category. In the “Equivalence” column, “equivalent” means the telemedicine exam and the in-person exam were equivalent, “inferior” means the telemedicine exam was inferior to the in-person exam, and “NS” means the equivalence between the telemedicine exam and the in-person exam was not specified

From: A scoping review of the unassisted physical exam conducted over synchronous audio-video telemedicine

Category of physical exam

Study

Title

Specific exam maneuvers

Outcome measure

Equivalence

Abdomen

Nachum 2019

Use of Physician-Guided Patient Self-Examination to Diagnose Appendicitis: A Telemedicine Case Report.

Abdominal self-palpation

Comparison against in-person exam

Equivalent

Cardiovascular

Cox 2013

Assessing exercise capacity using telehealth: A feasibility study in adults with cystic fibrosis

3-min step test

Comparison against in-person exam

Equivalent

Cardiovascular

Seuren 2020

Physical Examinations via Video for Patients With Heart Failure: Qualitative Study Using Conversation Analysis

Fluid retention (by the patient or relative feeling for leg edema), blood pressure with pulse rate and rhythm (using a self-inflating blood pressure monitor incorporating an irregular heartbeat indicator and put on by the patient or relative), oxygen saturation (using a finger clip device)

Explore the opportunities and challenges of remote physical examination of patients with heart failure using video-mediated communication technology

NS

Head and neck

Akhtar 2018

Telemedicine Physical Examination Utilizing a Consumer Device Demonstrates Poor Concordance with In-Person Physical Examination in Emergency Department Patients with Sore Throat: A Prospective Blinded Study

Oropharyngeal coloration, posterior pharynx asymmetry, uvular deviation, oropharynx exudate, swelling, and ulceration, head and neck lymph nodes

Comparison against in-person exam

Inferior

Multi-system

Bell 2016

Telemedicine versus face-to-face evaluations by respiratory therapists of mechanically ventilated neonates and children: A pilot study

Pressure control, PEEP, mean airway pressure, breathing frequency, FIO2, inspiratory to expiratory time ratio (I-E ratio), tidal volume (VT), minute ventilation, oxygen saturation, presence of patient-triggered breaths, the need for suctioning or increased ventilator support

Comparison against in-person exam

Equivalent

Multi-system

Duffy 1997

Telemedicine and the diagnosis of speech and language disorders

Oral mechanism exam, motor speech exam, language exam

Summarize our speech pathology consultation-by-satellite experience, with emphasis on the methods used, information obtained, difficulties encountered and overcome, and types of speech and language problems that have been evaluated through this medium

NS

Multi-system

Gallar 2007

Two-year experience with telemedicine in the follow-up of patients in home peritoneal dialysis

Catheter exit site appearance, dialysis fluid appearance, leg edema

Utility and cost-effectiveness of telemedicine in peritoneal dialysis

NS

Multi-system

Jenkins 2001

Assessing elderly patients with congestive heart failure via in-home interactive telecommunication

Assessment of respiratory effort, retraction, color of lips and nail beds, pedal and ankle edema

Comparison against in-person exam

Equivalent

Multi-system

Schoenfeld 2016

Variation in quality of urgent health care provided during commercial virtual visits

Ability to walk, tenderness at lateral malleolus, fever, tonsillar exudates, tender cervical adenopathy, suprapublic/flank/back pain

Completeness of histories and physical examinations via telemedicine, the correct diagnosis (vs an incorrect or no diagnosis), and adherence to guidelines of key management decisions.

Inferior

Multi-system

Siew 2016

Reliability of telemedicine in the assessment of seriously ill children

Respiratory Observation Checklist consisting of age-appropriate tachypnea, perioral cyanosis, nasal flaring, tripoding, thoracoabdominal asynchrony, supraclavicular, substernal, and intercostal retractions, mental status, and overall impression of respiratory distress. Yale Observation Scale consisting of quality of cry, reaction to parent stimulation, state variation or ability to be aroused, color, hydration status, and response to social overtures.

Comparison against in-person exam

Equivalent

Musculoskeletal

Abel 2017

Can Telemedicine Be Used for Adolescent Postoperative Knee Arthroscopy Follow-up?

Knee range of motion, incision color, effusion size

Comparison against in-person exam

Equivalent

Musculoskeletal

Cabana 2010

Interrater agreement between telerehabilitation and face-to-face clinical outcome measurements for total knee arthroplasty

Scar assessment, swelling of knee joint, muscle strength, locomotion (Tinetti test), balance (Berg test)

Comparison against in-person exam

Equivalent

Musculoskeletal

Goldstein 2019

Video examination via the smartphone: A reliable tool for shoulder function assessment using the constant score.

Constant score (CS)—pain, activity level, arm positioning, strength (assisted by spring device, should exclude this), range of motion

Comparison against in-person exam

Equivalent

Musculoskeletal

Good 2012

Skype: A tool for functional assessment in orthopaedic research

Oxford shoulder score, Constant shoulder score

Comparison against in-person exam (the agreement had to do with the angle measurements)

Equivalent

Musculoskeletal

Jacobson 2016

Telehealth Videoconferencing for Children With Hemophilia and Their Families: A Clinical Project

Appearance of blood, swelling, range of motion

Evaluate the feasibility of using telehealth videoconferencing in children with severe hemophilia in the home setting.

NS

Musculoskeletal

Lade 2012

Validity and reliability of the assessment and diagnosis of musculoskeletal elbow disorders using telerehabilitation

Observations, self-palpate, conduct range of motion tests with self-applied overpressure, perform self-resisted static muscle tests, self-applied special orthopedic tests, self-applied ULNT tests

Comparison against in-person exam

Equivalent

Musculoskeletal

Richardson 2017

Physiotherapy assessment and diagnosis of musculoskeletal disorders of the knee via telerehabilitation

Self-palpation, self-applied modified orthopedic tests such as pain intensity with passive varus force by verbal guidance, active movements

Comparison against in-person exam

Equivalent

Musculoskeletal

Russell 2013

Internet-based physical assessment of people with Parkinson disease is accurate and reliable: a pilot study.

Timed stance test, Timed Up and Go test, step test, steps in 360 degree turn, Berg Balance Scale, lateral and functional reach test

Comparison against in-person exam

Equivalent

Musculoskeletal

Steele 2012

Assessment and diagnosis of musculoskeletal shoulder disorders over the internet

Postural analysis, joint palpation, range of motion (ROM) testing at the shoulder and adjacent joints, static muscle tests (SMTs), special orthopedic tests, neural testing, Hawkins-Kennedy impingement test

Comparison against in-person exam

Equivalent

Musculoskeletal

Turner 2018

Case Studies in Physical Therapy: Transitioning A "Hands-On" Approach into A Virtual Platform.

Range of motion

Feasibility of performing musculoskeletal exam over telemedicine

NS

Neurologic

Abdolahi 2016

A feasibility study of conducting the Montreal Cognitive Assessment remotely in individuals with movement disorders

MoCA

Comparison against in-person exam

Equivalent

Neurologic

Ali 2013

Accuracy of remote video cellphone evaluation of stroke deficits using california brief stroke scale

California Brief Stroke Scale (CABSS), a prehospital telemedicine instrument to rate stroke severity

Comparison against in-person exam

Equivalent

Neurologic

Andrzejewski 2015

Determining the reliability of performing the modified unified Parkinson's disease rating scale (UPDRS) remotely in a pilot virtual visit study in the home

Modified (excluding rigidity and postural instability) Unified Parkinson’s disease Rating Scale (mUPDRS)

Comparison against in-person exam

Equivalent

Neurologic

Ball 1993

Preliminary evaluation of a low-cost VideoConferencing (LCVC) system for remote cognitive testing of adult psychiatric patients

MMSE

Comparison against in-person exam

Equivalent

Neurologic

Bove 2019

Toward a low-cost, in-home, telemedicine-enabled assessment of disability in multiple sclerosis

Expanded Disability Status Scale (EDSS)

Comparison against in-person exam

Equivalent

Neurologic

Bull 2014

Conducting the montreal cognitive assessment remotely in Huntington's disease

MoCA

Comparison against in-person exam

Equivalent

Neurologic

Bull 2014

Monitoring fluctuations in motor function and mood hourly in Parkinson's disease via telemedicine

Modified version the Unified Parkinson’s disease Rating Scale (mUPDRS)

Correlation of mUPDRS with subjective mood and mobility ratings by patient on 1–10 scale

Equivalent

Neurologic

Carotenuto 2018

Cognitive Assessment of Patients With Alzheimer's Disease by Telemedicine: Pilot Study.

Italian versions of the MMSE and Alzheimer’s Disease Assessment Scale cognitive subscale (ADAS-cog)

Comparison against in-person exam

Equivalent

Neurologic

Castanho 2016

Assessing Cognitive Function in Older Adults Using a Videoconference Approach

The Telephone Interview for Cognitive Status-Modified--Portuguese version (TICSM-PT)

Comparison of videoconference exam against telephone and in-person exam

Equivalent

Neurologic

Cullum 2006

Feasibility of telecognitive assessment in dementia

MMSE, Hopkins Verbal Learning Test-Revised, Clock Drawing Test, Digit Span, Category Fluency (fruits and vegetables), letter fluency (FAS and CFL versions), 15-item versions of the Boston Naming Test

Comparison against in-person exam

Equivalent

Neurologic

Davis 2014

Teleneurology: Successful Delivery of Chronic Neurologic Care to 354 Patients Living Remotely in a Rural State

Full neurologic exam with the exception of deep tendon reflexes, a careful sensory exam, retinal exam, or complete oral exam of palate movement

Patient satisfaction with teleneurology care as measured by a performance improvement satisfaction questionnaire

NS

Neurologic

Davis 2019

Using Teleneurology to Deliver Chronic Neurologic Care to Rural Veterans: Analysis of the First 1,100 Patient Visits

Mental status exam, cranial nerve exam (eye movements, nystagmus, eye closure strength, speech, protrusion of their tongue, and neck rotation), motor exam (bradykinesia and involuntary movement assessment, patients were asked to hold their arms outstretched, perform repetitive movements with fingers and hands, stand up from their chair without using their arms, and walk around the room), coordination and balance (walk tandem, perform a Romberg test, rapidly move their fingers in sequence, and perform finger to nose and rapid alternating movement tests)

Survey measuring quality of care, ease of communication, satisfaction, and staff’s ability to deliver same quality care as in person.

NS

Neurologic

DeYoung 2019

The reliability of the Montreal Cognitive Assessment using telehealth in a rural setting with veterans.

Montreal Cognitive Assessment

Comparison against in-person exam

Equivalent

Neurologic

Dorsey 2015

Feasibility of virtual research visits in fox trial finder

Montreal Cognitive Assessment, MDS-UPDRS (excluding rigidity and balance)

Determine feasibility of virtual research visits, validate self-reported diagnosis of volunteers, and gauge satisfaction of neurologists and patients with visit through survey

NS

Neurologic

Fraint 2019

Reliability, feasibility and satisfaction of telemedicine evaluations for Cervical Dystonia.

Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) motor severity subscale

Comparison against in-person exam

Equivalent

Neurologic

Hubble 1993

Interactive video conferencing: a means of providing interim care to Parkinson's disease patients.

Unified PD Rating Scale (UPDRS), Hoehn and Yahr score

Comparison against in-person exam

Equivalent

Neurologic

Korn 2017

Virtual visits for Parkinson disease: A multicenter noncontrolled cohort

Parkinson’s disease-focused exam

The primary outcome measures were feasibility, as measured by the proportion of visits completed as scheduled, and the 6-month change in quality of life, as measured by the Parkinson’s Disease Questionnaire 39. Additional outcomes included satisfaction with visits and interest in future virtual visits.

NS

Neurologic

Lindauer 2017

Dementia Care Comes Home: Patient and Caregiver Assessment via Telemedicine

MoCA

Comparison against in-person exam

Equivalent

Neurologic

Loh 2007

Development of a telemedicine protocol for the diagnosis of Alzheimer's disease

Standardized Mini Mental State Examination, Geriatric Depression Scale, Katz assessment of Activities of Daily Living, Instrumental ADL assessment, the Informant Questionnaire for Cognitive Decline in the Elderly

comparison against in-person exam, agreement for diagnosis of Alzheimer's between telemedicine and in-person exam

Equivalent

Neurologic

McEachern 2008

Reliability of the MMSE administered in-person and by telehealth

Mini-mental status examination (MMSE)

Comparison against in-person exam

Equivalent

Neurologic

Montani 1997

Psychological impact of a remote psychometric consultation with hospitalized elderly people

Mini-mental state exam (MMSE), clock face test (CFT)

Comparison against in-person exam

Inferior

Neurologic

MunroCullum 2014

Teleneuropsychology: evidence for video teleconference-based neuropsychological assessment

Mini-Mental State Examination (MMSE), Hopkins Verbal Learning Test-Revised, Digit Span forward and backward, short form Boston Naming Test, Letter and Category Fluency, Clock Drawing

Comparison against in-person exam

Equivalent

Neurologic

Palsbo 2007

Televideo assessment using Functional Reach Test and European Stroke Scale

European Stroke Scale (ESS), the Functional Reach Test (FRT)

Comparison against in-person exam

Equivalent

Neurologic

Park 2017

Korean Version of the Mini-Mental State Examination Using Smartphone: A Validation Study

Korean version of the Mini-Mental State Examination (MMSE-K)

Comparison against in-person exam

Equivalent

Neurologic

Rudolph 2014

Tablet computers address limitations of telestroke systems

NIH stroke scale

Comparison against in-person exam

Equivalent

Neurologic

Shores 2004

Identifying undiagnosed dementia in residential care veterans: Comparing telemedicine to in-person clinical examination

Focused neurological exam (gait, eye movements, hand tremor, and frontal release signs), short Blessed, three world recall, clock drawing

Agreement between in-person and telemedicine exams on diagnosis of dementia

Equivalent

Neurologic

Stillerova 2016

Remotely assessing symptoms of Parkinson's disease using videoconferencing: A feasibility study

Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS)

Comparison against in-person exam

Inferior

Neurologic

Stillerova 2016

Could everyday technology improve access to assessments? A pilot study on the feasibility of screening cognition in people with Parkinson's disease using the Montreal Cognitive Assessment via Internet videoconferencing

MoCA

Comparison against in-person exam

Equivalent

Neurologic

Tarolli 2018

Virtual research visits in individuals with Parkinson disease enrolled in a clinical trial: React-PD study

Parkinson's disease motor and symptom assessments

Comparison against in-person exam

NS

Neurologic

Timpano 2013

Videoconference-based mini mental state examination: a validation study

Italian videoconference-based version of the Mini-Mental State Examination (VMMSE)

Comparison against in-person exam

Equivalent

Neurologic

Vahia 2015

Telepsychiatry for neurocognitive testing in older rural latino adults

Mini-Mental State Examination (MMSE), Hopkins Verbal Learning Test (HVLT)-Revised, Digit Span subtest from the Escala de Inteligencia de Wechsler para Adultos-Tercera Edicion, Letter and Category Fluency, Clock Drawing, Brief Visuospatial Memory Test (revised) (BVMT-R), Ponton-Satz Spanish Naming Test

Comparison against in-person exam

Equivalent

Neurologic

VanHooff 2013

Prehospital unassisted assessment of stroke severity using telemedicine: A feasibility study

Unassisted TeleStroke Scale (UTSS)

Comparison against in-person exam

Equivalent

Neurologic

VanHooff 2013

Unassisted assessment of stroke severity using telemedicine

Unassisted TeleStroke Scale (UTSS)

Comparison against in-person exam

Equivalent

Neurologic

Venkataraman 2014

Virtual visits for Parkinson disease: A case series

components of the Unified Parkinson’s Disease Rating Scale, such as remote analysis of rest tremor, action tremor, finger taps, hand movements, arising from chair, and gait

Feasibility, patient satisfaction

NS

Neurologic

Wadsworth 2016

Remote Neuropsychological Assessment in Rural American Indians with and without Cognitive Impairment

MMSE, Clock Drawing, Digit Span Forward and Backward, Oral Trails, Hopkins Verbal Learning Test-Revised, Letter and Category Fluency, a short form Boston Naming Test

Comparison against in-person exam

Equivalent

Neurologic

Weiner 2011

Videoconference diagnosis and management of Choctaw Indian dementia patients

eyesight, hearing, facial expression, gait and station, coordination, tremor, rapid alternating movements, psychomotor activity, motor tests of executive function

Feasibility

NS

Neurologic

Wong 2012

The Rowland universal dementia assessment scale (RUDAS) as a reliable screening tool for dementia when administered via videoconferencing in elderly post-acute hospital patients

Rowland Universal Dementia Assessment Scale (RUDAS)

Comparison against in-person exam

Equivalent

Neurologic

Wood 2013

Can a low-cost webcam be used for a remote neurological exam?

Kurtzke Expanded Disability Status Scale (EDSS)

Comparison against in-person exam

Equivalent

Neuropsychologic

Appleby 2019

Feasibility of remote assessment of human prion diseases for research and surveillance

Telephone Interview for Cognitive Status (TICS), Medical Research Council (MRC) Prion Disease Rating Scale, Neuropsychiatric Inventory Questionnaire (NPI-Q), neurological exam

Acceptance, ease of use, and satisfaction of teleneurology among subjects and their caregivers

NS

Neuropsychologic

Galusha-Glasscock 2016

Video Teleconference Administration of the Repeatable Battery for the Assessment of Neuropsychological Status

Repeatable Battery for the Assessment of Neuropsychological Status (RBANS)

Comparison against in-person exam

Equivalent

Neuropsychologic

Hildebrand 2004

Feasibility of neuropsychological testing of older adults via videoconference: Implications for assessing the capacity for independent living

Rey Auditory Verbal Learning Test (RAVLT)-T1, RAVLT- T6, RAVLT-LOT, CD, MR, BTA, CWAT, RAVLT-D, VOC

Comparison against in-person exam

Equivalent

Neuropsychologic

Kirkwood 2000

The consistency of neuropsychological assessments performed via telecommunication and face to face

National Adult Reading Test (NART) 11, the Quick Test, Forms 1 and 3, and sections of the Adult Memory and Information Processing Battery (AMIPB) 13, comprising Forms 1 and 2 of the following subtests: Story Recall, List Learning, Figure Recall, Information Processing

Comparison against in-person exam

Equivalent

Neuropsychologic

Vestal 2006

Efficacy of language assessment in Alzheimer's disease: comparing in-person examination and telemedicine.

Picture Description (auditory response version) (Boston Diagnostic Aphasia Examination [BDAE]) (Goodglass et al 2001), Boston Naming Test (BNT) (Goodglass et al 2001), Token Test (Multilingual Aphasia Examination) (Benton et al 2000), Aural Comprehension of Words and Phrases (Benton et al 2000), Controlled Oral Word Association Test (Benton et al 2000)

Comparison against in-person exam

Equivalent

Not specified

Dixon 2008

Virtual visits in a general medicine practice: A pilot study

not specified

Comparison against in-person exam

Inferior

Not specified

Ohta 2017

How Accurate Are First Visit Diagnoses Using Synchronous Video Visits with Physicians?

not specified

Agreement between in-person and telemedicine diagnoses

Equivalent

Psychiatric

Grosch 2015

Video teleconference-based neurocognitive screening in geropsychiatry

Mini-Mental State Examination (MMSE), Clock Drawing Test, Digit Span

Comparison against in-person exam

Equivalent

Psychiatric

Loh 2004

Can patients with dementia be assessed at a distance? The use of Telehealth and standardised assessments

Standardized Mini-Mental State Exam (SMMSE), the Geriatric Depression Scale (GDS)

Comparison against in-person exam

Inferior

Psychiatric

Menon 2001

Evaluation of a portable low cost videophone system in the assessment of depressive symptoms and cognitive function in elderly medically III veterans

Geriatric Depression Scale short version (GDS), Hamilton Depression Scale (HAM-D), Short Portable Mental Status Exam (SPMSE)

Comparison against in-person exam

Equivalent

Psychiatric

Singh 2007

Accuracy of telepsychiatric assessment of new routine outpatient referrals

Not specified

Agreement of DSM-IV diagnoses, risk assessment, non-drug and drug interventions between telemedicine and in-person exams

Equivalent

Skin

Edison 2008

Diagnosis, diagnostic confidence, and management concordance in live-interactive and store-and-forward teledermatology compared to in-person examination

Not specified

Diagnostic and management agreement between in-person and telemedicine exams

Equivalent

Skin

Lesher 1998

Telemedicine evaluation of cutaneous diseases: a blinded comparative study.

Not specified

Agreement in diagnoses between the telemedicine and in-person groups.

Equivalent

Skin

Marchell 2017

Comparing High Definition Live Interactive and Store-and-Forward Consultations to In-Person Examinations

Not specified

Diagnoses, decisions to biopsy, and diagnostic confidence for teledermatology consultations vs in-person

Inferior

Skin

Seghers 2014

A prospective study on the use of teledermatology in psychiatric patients with chronic skin diseases

Not described, but likely only visual inspection.

Comparison against in-person exam

Equivalent

Skin

Smith 2004

Diagnostic accuracy of and patient satisfaction with telemedicine for the follow-up of paediatric burns patients

Scar color, scar thickening, contractures, range of motion, breakdown of the graft site, activity level

Comparison against in-person exam

Equivalent