Table 2 Summary of global and component ratings of each study
From: The effect of medical cannabis on cognitive functions: a systematic review
| Â | Selection bias | Study design | Blinding | Data collection method | Withdrawals and dropouts | Global rating |
|---|---|---|---|---|---|---|
Sativex spray | ||||||
 Alessandria, 2020 [9] | Moderate | Moderate | Weak | Strong | Weak | Weak |
 Aragona, 2009 [22] | Moderate | Strong | Moderate | Strong | Strong | Strong |
 Cooper, 2017 [23] | Weak | Strong | Moderate | Strong | Strong | Moderate |
 Rog, 2005 [14] | Moderate | Strong | Moderate | Strong | Strong | Strong |
 Vachová, 2014 [15] | Moderate | Strong | Moderate | Strong | Strong | Strong |
 Wade, 2004 [24] | Moderate | Strong | Moderate | Moderate | Strong | Strong |
 Russo, 2016 [25] | Moderate | Moderate | Weak | Strong | Strong | Moderate |
 Castelli, 2018 [26] | Weak | Moderate | Weak | Strong | Weak | Weak |
Epidiolex | ||||||
 Martin, 2019 [17] | Moderate | Moderate | Weak | Strong | Weak | Weak |
 Metternich, 2020 [27] | Moderate | Moderate E | Weak | Strong | Strong | Moderate |
Other spray | ||||||
 Almog, 2020 [28] | Moderate | Strong | Moderate | Strong | Strong | Strong |
 Wade, 2003 [29] | Weak | Strong | Moderate | Moderate | Strong | Moderate |
Gelatin capsules | ||||||
 Müller-Vahl, 2001 [30] | Weak | Strong | Moderate | Strong | Strong | Moderate |
 Müller-Vahl, 2003 [31] | Weak | Moderate | Moderate | Strong | Strong | Moderate |
 Vaney, 2004 [16] | Moderate | Strong | Moderate | Strong | Moderate | Strong |
Smocked or vaped | ||||||
 Corey-Bloom, 2012 [11] | Weak | Strong | Moderate | Strong | Strong | Moderate |
 Wallace, 2015 [12] | Moderate | Strong | Moderate | Strong | Strong | Strong |
 Wilsey, 2008 [13] | Moderate | Strong | Moderate | Strong | Strong | Strong |
 Wilsey, 2013 [32] | Moderate | Strong | Moderate | Strong | Strong | Strong |
 Abdallah, 2018 [33] | Moderate | Strong | Moderate | Weak | Strong | Moderate |
Other | ||||||
 Bar-Sela, 2019 [34] | Weak | Moderate | Weak | Strong | Weak | Weak |
 Gustavsen, 2021 [35] | Moderate | Moderate | Weak | Strong | Strong | Moderate |
Withdrawal | ||||||
 Feinstein, 2019 [10] | Weak | Strong | Weak | Strong | Strong | Weak |