Table 2 Characteristics of selected records
From: The incidence of TB and MDR-TB in pediatrics and therapeutic options: a systematic review
Author, year and reference | Research Question(s) or Objective(s) | Research Design | Study Country (Location) | Duration of Study | Sample Size (and Study Population) | Age of Participants (years) | Co-morbidity(ies) |
|---|---|---|---|---|---|---|---|
Gledovic et al. 2006 [13] | The objective of this study was to establish the tuberculosis incidence and mortality in children in Serbia in the period 1992-2002 | Retrospective | Serbia | 1992 - 2002 | 135000 Male and Female | 0-14 years | Missing |
Padayatchi et al. 2006 [17] | Investigation into Multidrug-Resistant Tuberculous Meningitis in Children in Durban, South Africa | Retrospective | Durban, South Africa | 1992-2003 | 8 Male and Female | 0-11 years | HIV |
Fairlie et al. 2011 [18] | The aim of this study was to review the prevalence and clinical outcome of childhood MDR-TB at two hospitals in Johannesburg, South Africa. | Retrospective | Gauteng, South Africa | 2008 | 1317 Male and Female | <14 years | HIV |
Seddon et al. 2012 [9] | To describe the clinical presentation, treatment, and outcome for a large cohort of children with confirmed MDR-tuberculosis and evaluate factors influencing treatment response. | Retrospective cohort | Western Cape , South Africa | 1st January 2003 to 31st December 2008 | 111 Male and Female | Median age= 50 months | HIV |
Erkens et al. 2014 [19] | The objective of the study was to describe the occurrence of TB events among children in the Netherlands | Retrospective | Netherlands | 1993-2012 | 8357 Male and Female | <14 years | Missing |
Nabukeera-Barungi et al. 2014 [20] | Investigation into the presentation and outcome of tuberculous meningitis among children | Retrospective | South Africa | 1st January 2009 to 31st December 2009 | 40 Male and Female | Median age=32 months | HIV |
Ben Ayed et al. 2019 [21] | The study aimed to give an update about the epidemiological profile of childhood TB in south of Tunisia and to describe their chronological trends from 1995 to 2016. | Retrospective | Southern Tunisia | 1st January 1995 to 31st December 2016 | 204 Male and Female | <15 years | Missing |
Wang et al. 2020 [22] | The study aimed to analyse the epidemiological and clinical characteristics, as well as drug resistance in culture-confirmed children with Tuberculosis meningitis (TBM) in Southwest of China. | Retrospective | Public Health Clinical Center of Chengdu, China | January 2013 and December 2018 | 319 Male and Female | <14 years | Missing |
Zhou et al. 2020 [23] | To evaluate the prevalence of MDR-TB among children age ≤15 years old, from 2008 to 2018. | Retrospective | Shandong Provincial Chest Hospital, Shandong- China | 2008 to 2013 and 2014 to 2018. 10 years | 222 Male and Female | Mean age of children was 10.7 ± 4.8 years (range from 3 months to 15 years) | Missing |