Skip to main content

Table 2 Seroprevalence and incidence of CMV infection among healthcare and childcare workers

From: Prevalence, incidence, and risk factors associated with cytomegalovirus infection in healthcare and childcare worker: a systematic review and meta-analysis

 

CMV seropositivity

CMV primary infection

Covariates

Number of studies

Sample size

Proportion % (95 % CI)

I2% (95% CI)

Number of studies

Person-year

Incidence % per year (95% CI)

I2 % (95% CI)

Overall prevalence

47

29332

53.3 (46.5–60.0)

98 (98–98)

21

3994

4.6 (2.6–7.1)

83 (76–89)

Groups*

 Childcare workers

24

22194

59.3 (49.8–68.6)

98 (97–98)

9

883

7.4 (3.9–11.8)

89 (81–93)

 Healthcare workers

25

7138

49.5 (40.3–58.7)

97 (97–98)

12

3111

3.1 (1.3–5.6)

48 (0–73)

Region

 Africa

3

95

47.9 (18.5–78.0)

96 (91–98)

-

   

 North America

26

6781

46.6 (37.9–55.5)

94 (92–95)

15

3272

5.9 (3.3–9.0)

87 (80–91)

 Asia

2

1242

77.9 (49.1–96.8)

91 (68–97)

1

70

2.8 (0.0–8.4)

-

 Europe

15

20924

61.2 (50.2–71.7)

99 (98–99)

3

352

1.1 (0.0–7.4)

15 (0–91)

 Oceania

1

290

52.1 (46.3–57.8)

 

2

300

2.3 (0.0–10.3)

62 (0–91)

Diagnostic method

 Anticomplement immunofluorescence

4

1466

60.5 (39.4–79.7)

97 (95–98)

3

1208

2.6 (0.1–7.3)

17 ( 0–91)

 Complement fixation

7

1636

48.6 (31.4–65.9)

98 (97–99)

5

1178

4.4 (1.2–9.2)

72 (29–89)

 ELISA

18

5245

53.1 (42.7–63.3)

98 (95–97)

5

1169

5.0 (1.8–9.5)

93 (88–97)

 Latex agglutination

6

795

47.0 (28.9–65.5)

90 (81–95)

4

258

7.9 (2.8–15.1)

0 (0–85)

 No specify

3

644

24.6 (7.1–48.0)

98 (97–99)

1

42

23.8 (12.0–38.0)

-

 Other

7

19496

66.0 (50.4–80.1)

95 (92–97)

2

125

1.0 (0.0–7.1)

45 (–)

 Restriction endonuclease

2

50

76.0 (41.3–98.8)

42 (–)

1

14

0.0 (0.0–11.9)

-

Study design

 Cohort

25

7548

52.1 (42.8–61.3)

97 (97–98)

21

3994

4.6 (2.6–7.1)

83 (76–89)

 Cross-sectional

22

21784

54.7 (44.6–64.6)

98 (97–98)

-

   

Quality

 Good

19

7584

58.9 (48.8–68.7)

98 (97–98)

10

2590

5.8 (2.7–9.8)

88 (79–93)

 Fair

13

3160

51.1 (38.8–63.3)

96 (95–97)

8

1044

3.5 (0.7–7.8)

67 (30–84)

 Poor

15

18588

46.7 (33.7–59.8)

98 (97–98)

3

359

3.9 (0.1–11.4)

92 (80–97)

  1. CI Confidence interval, I2Statistic for heterogeneity. *Two studies included childcare and healthcare workers