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Table 2 Referral recommendations for each TEAE

From: Ocular adverse events from pharmacological treatment in patients with multiple sclerosis—A systematic review of the literature

TEAEs

Referral

Papilledema

Neurologist, priority attention

Conjunctivitis

Ophthalmologist

Herpes zoster ophtalmicus

Ophthalmologist and refer depending on the compromise

Visual disturbance

Ocular inflammation

Macular edema

Ophthalmologist, if available retina specialist

Retinal branch vein occlusion

Macular hemorrhage

Retinal hemorrhages and macular edema

Retinopathy

Intraretinal hemorrhages

Retina peripheral bilateral telangiectasiae

Neuroretinitis

Retinal detachment

Acute retinal necrosis

Ocular toxoplasmosis reactivation

Ophthalmologist, if available retina or uvea specialist

Uveitis

Ophthalmologist, if available uvea specialist

Abnormal visual evoked potentials

Ophthalmologist, if available neuro-ophthalmologist

Visual field defect

Progressive multifocal leukoencephalopathy by JCV

Optic ischemic neuropathy

Diplopia

Thyroid eye disease

Endocrinologist and ophthalmologist, if available oculoplastics specialist

Eyelid edema

Ophthalmologist, if available oculoplastics specialist

Conjuctival lymphoma

Idiopathic orbital inflammation

Ophthalmologist, if available ocular surface specialist

Sjogren syndrome

Rheumatologist and ophthalmologist, if available ocular surface specialist

Corneal edema

Ophthalmologist, if available cornea specialist