Table 1 Summary of eligible studies
Author; year | Gender; strain; species | Sample size SCI; treated | Model | Severity of injury | Injury to treatment interval (day) | Location of injury | Immunosuppressive; antibiotic | Transplantation type | Number of transplanted cell | Follow-up (week) |
|---|---|---|---|---|---|---|---|---|---|---|
Abdanipour; 2014 [13] | Female; Sprague–Dawley; rat | 8; 8 | Contusion | Moderate | 7 | Lumbar | No; Yes | IS/IT | 3 × 105 | 12 |
Aras; 2016 [14] | Female; Wistar; rat | 7; 14 | Compression | Severe | 0, 9 | Thoracolumbar | No; No | IS/IT | 3 × 105 | 4 |
da Silva; 2014 [22] | NR; Wistar; rat | 12; 12 | Compression | Moderate | 7, 14 | Thoracic | No; Yes | IV | 1.2 × 106 | 13 |
Kang; 2006 [15] | Female; Wistar; rat | 3; 3 | Hemisection | Severe | 3 | Thoracolumbar | No; No | IV | 2 × 106 | 4 |
Menezes; 2014 [23] | Female; Sprague–Dawley; rat | 9; 9 | Compression | Moderate | 0 | Thoracic | No; Yes | IS/IT | NR | 8 |
Min; 2017 [24] | Female; Sprague–Dawley; rat | 5; 8 | Contusion | Severe | 3, 7, 14 | Thoracic | No; Yes | IS/IT | 1 × 106 | 8 |
Oh; 2012 [25] | Male; Sprague–Dawley; rat | 10; 10 | Compression | Severe | 0 | Thoracic | No; No | IS/IT | 1 × 105 | 6 |
Ohta; 2017 [26] | Female; Sprague–Dawley; rat | 15; 20 | Contusion | Moderate | 8 | Thoracolumbar | No; Yes | IV | 2.5 × 106 | 7 |
Ohta; 2018 [27] | Female; Sprague–Dawley; rat | 8; 10 | Contusion | Moderate | 8 | Thoracolumbar | No; Yes | IV | 2.5 × 106 | 6 |
Rosado; 2017 [28] | Male; Wistar; Rat | 50; 50 | Compression | Moderate | 0 | Thoracic | No; Yes | IV | 1 × 106 | 3 |
Sarveazad; 2014 [30] | Male; Wistar; rat | 6; 6 | Contusion | Moderate | 7 | Thoracic | No; Yes | IS/IT | 1 × 106 | 8 |
Sarveazad; 2017 [29] | Male; Wistar; rat | 6; 6 | Contusion | Moderate | 7 | Thoracic | No; Yes | IS/IT | 1 × 106 | 9 |
Tang; 2016 [31] | Female; Sprague–Dawley; rat | 16; 16 | Contusion | Severe | 9 | Thoracic | No; No | IS/IT | 1 × 106 | 8 |
Wang; 2017 [16] | Male; Sprague–Dawley; rat | 76; 76 | Crush | Moderate | 0 | Thoracic | No; Yes | IS/IT | 1 × 106 | 4 |
Zhang; 2009 [32] | Male; Sprague–Dawley; rat | 12; 12 | Contusion | Moderate | 7 | Thoracic | No; No | IS/IT | NR | 11 |
Zhang; 2014 [33] | Male; Sprague–Dawley; rat | 15; 15 | Crush | Moderate | 0 | Thoracolumbar | Yes; Yes | IS/IT | 2 × 105 | 3 |
Zheng; 2017 [34] | Female; Sprague–Dawley; rat | 12; 12 | Hemisection | Severe | 0 | Thoracolumbar | No; No | IS/IT | 1 × 106 | 7 |
Zhou; 2013 [35] | Female; Sprague–Dawley; rat | 5; 5 | Hemisection | Severe | 0 | Thoracic | Yes; No | IS/IT | 2 × 105 | 4 |