|
Echocardiographic parameters
|
Number of studies
|
OSA/control
|
SMD (95% CI)
|
p value
|
Study heterogeneity
|
Egger’s test p value
|
|---|
|
I2
|
χ2
|
p value
|
|---|
|
LAD (mm)
|
13
|
1107/317
|
0.385 (0.252, 0.518)
|
< 0.001
|
39.1%
|
19.72
|
0.073
|
0.757
|
|
LAVI (ml/m2)
|
6
|
238/163
|
0.307 (0.096, 0.518)
|
0.004
|
89.50%
|
47.49
|
< 0.001
|
0.036
|
|
LVESD (mm)
|
24
|
1526/620
|
0.323 (0.223, 0.422)
|
< 0.001
|
0.00%
|
14.8
|
0.902
|
0.646
|
|
LVEDD (mm)
|
18
|
918/406
|
0.126 (0.003, 0.249)
|
0.044
|
0.00%
|
13.98
|
0.669
|
0.638
|
|
LVM (g)
|
7
|
708/612
|
0.558 (0.403, 0.712)
|
< 0.001
|
87.3%
|
47.42
|
< 0.001
|
0.807
|
|
LVMI (g/m2)
|
23
|
1515/641
|
0.478 (0.242, 0.714)
|
< 0.001
|
81.3%
|
117.7
|
< 0.001
|
0.562
|
|
IVSD (mm)
|
24
|
1375/808
|
0.471 (0.195, 0.747)
|
0.001
|
87.1%
|
177.71
|
< 0.001
|
0.021
|
|
PWD (mm)
|
22
|
1348/1047
|
0.602 (0.328, 0.875)
|
< 0.001
|
86.7%
|
157.47
|
< 0.001
|
0.087
|
|
LVEF (%)
|
39
|
2552/1737
|
− 0.238 (− 0.379, − 0.097)
|
0.001
|
73.4%
|
142.76
|
< 0.001
|
0.465
|
|
LV MPI
|
8
|
512/385
|
0.687 (0.371, 1.004)
|
< 0.001
|
74.4%
|
27.38
|
< 0.001
|
0.915
|
|
RVD (mm)
|
15
|
845/470
|
0.725 (0.605, 0.845)
|
< 0.001
|
82.7%
|
80.8
|
< 0.001
|
0.184
|
|
RV MPI
|
8
|
303/346
|
0.881 (0.487, 1.274)
|
< 0.001
|
79.4%
|
33.98
|
< 0.001
|
0.052
|
|
TAPSE
|
10
|
435/419
|
− 0.481 (− 0.810, − 0.152)
|
0.004
|
79.0%
|
42.9
|
< 0.001
|
0.12
|
|
RV FAC
|
5
|
762/234
|
− 0.399 (− 0.553, − 0.246)
|
< 0.001
|
0.00%
|
2.59
|
0.629
|
0.222
|
- IVSD interventricular septum diameter, LAD left atrial diameter, LAVI left atrium volume index, LVEDD left ventricular end-diastolic diameter, LVESD left ventricular end-systolic diameter, LVM left ventricular mass, LVMI left ventricular mass index, LV MPI left ventricular myocardial performance index, LVEF left ventricular ejection fraction, OSA obstructive sleep apnea, PWD posterior wall diameter, SMD standardized mean difference, RVD right ventricular diameter, RV FAC right ventricular fractional area change, RV MPI right ventricular myocardial performance index, TAPSE tricuspid annular plane systolic excursion
