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Table 1 PICO framework used to generate this review

From: Effectiveness of matching human leukocyte antigens (HLA) in corneal transplantation: a systematic review protocol

Population

Patients (humans) undergoing corneal transplantation

Intervention

Donor-recipient HLA matching

Comparator

Patients receiving unmatched/selectively matched/randomly allocated donor corneas

Outcome

Occurrence of rejection and failure