Fig. 2

LFIA methodological quality summary table and graph. a Risk of bias and applicability concerns summary: review authors’ judgements about each domain for each included study. b QUADAS-2 bias assessment and QUADAS-2 applicability assessment item presented as percentages across all included studies. On the left, risk of bias graph and on the right applicability concerns graph. c Risk of bias and applicability concerns summary: review authors. Low, low risk of bias; high, high risk of bias; unclear, bias is unclear