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Table 4 Summary characteristics of eligible studies (n = 42). Studies not included in meta-analyses (n = 6) are marked with an asterisk (*)

From: Proactive psychological programs designed to mitigate posttraumatic stress injuries among at-risk workers: a systematic review and meta-analysis

Study (quality)

Sample size

Population (country)

Design

Program description

Program duration

Evaluation

Outcomes

Results

Alexander et al., 2015 [55] (Moderate-Low)

40

Nurses (USA)

RCT

Mindfulness-based stress management (Yoga) vs. Nil training

1 session (time not provided) × 8 weeks

Pre-training, post-training

HPLP-II; FMI; MBI EE, DP, PA subscales

Significant post-training improvements in self-care (HPLP-II), EE and DP

Andersen et al., 2015 [35] (Moderate-Low)

18

Special forces (SWAT) police officers (Finland)

Prospective cohort study

Psycho-educational and physiological resilience promotion with HRV-BF (iPREP)

5 days × 60 min sessions + 15 min daily breathing practice

Pre-training, post-training

HRmax; HRavg; respiratory achievement and coherence while listening to critical incident scenarios

Significant reductions in HRavg and improvement in respiratory achievement scores on Day 5 vs Day 1 of training, indicative of improved autonomic regulation under stress

Andersen & Gustafsberg, 2016 [36] (Moderate-High)

12

Special forces (SWAT) police officers (Finland)

RCT

Psycho-educational and physiological resilience promotion with HRV-BF (iPREP) vs. TAU

5 days total: 2 pre-post evaluation days, 3 training days

Pre-training, post-training

HRmax; HRRec to HRBase; BP; self-reported stress

At post-training evaluations, the iPREP group had significantly lower HRMax (scenario 1 only)

Andersen et al., 2018 [40] (Moderate-low)

57

Police officers (Canada)

Prospective cohort study

Psycho-educational and physiological resilience promotion with HRV-BF (iPREP)

4 days total: 1.5 days of pre and post-training evaluation, 2.5 days of training

Pre-training, post-training, 6, 12, and 18 months

HRMax and HRIndex during critical incident scenarios; HRRec

Significant reductions in HRIndex at 12 months follow-up, but not maintained at 18 months follow-up; HRRec faster at 12 and 18 months follow-up relative to pre- and post-training and 6 months follow-up

Anderson, Vaughan & Mills, 2017 [33] (Moderate-Low)

138

Primary care paramedical students performing a duty practicum (Canada)

RCT

Web-based psychoeducational resilience promotion vs. TAU

6-8 hours

Pre-training, post-training

RS global score and subscales

Resilience training significantly improved all measures except meaningfulness subscale following in-field practicum. SD values obtained from authors.

Arble et al., 2017 [56] (Moderate-High)

22

Police officers (USA)

Prospective cohort study

Psychoeducational resilience promotion and coping skill building

5 × 90 min group sessions

Pre-training, 12 months

COPE subscales; Sources of Support Scale; PCL; HADS; AUDIT

Following their first year in the field, officers appeared to report improved use of positive reframing and humor, and significant reductions in anxiety

Arnetz et al., 2009 [57] (Low)

18

Police officers (Sweden)

RCT

Psycho-educational and physiological resilience promotion and coping skill building vs. TAU

2 h × 10 weeks

12 months

Serum antithrombin and cortisol; mean change in HR; self-reported stress; POMS vigor-activity subscale and negative mood composite

Following their first year in the field, trained officers appeared to report less negative mood, smaller changes in mean HR and self-reported stress, and greater changes in antithrombin following a simulated critical incident

Arnetz et al., 2013 [58] (Moderate-High)

75

Police officers (Sweden)

RCT

Psycho-educational and physiological resilience promotion vs. TAU

90 min × 10 weeks + homework 3× per week

Pre-training, 18 months

GHQ, serum cortisol; prolactin; DHEA

Statistically significant post-training improvement in GHQ only

Bademci et al., 2016 [59] (Moderate-Low)

42

Correctional officers (Turkey)

Prospective cohort study

Psychosocial support program

75-min sessions, 3 times a week × 11 weeks (41.25 hs total)

Pre-training, post-training

PANAS; MBI EE, DP, PA subscales; BDI; BAI

Significant post-training improvements on all measures

Berger et al., 2016 [60] (Moderate-High)

63

Educational staff affected by the 2011 Christchurch earthquake (New Zealand)

RCT

Multimodal psychoeducational resilience promotion (EZ) vs. Critical incident management (METI)

3 × 8 h sessions for both treatments

Pre-training, post-training, 8 months

PCL; ProQoL CF, burnout, CS subscales; CDRS

Resilience higher pre-training in EZ, significantly improved post-training for both groups. Greater improvements in PCL and ProQoL subscales for EZ compared with METI

Berking et al., 2010 [61] (Moderate-Low)

31

Police officers (Switzerland)

Crossover RCT

Psycho-educational and physiological emotion regulation, cognitive therapy, coping skill building (iTEC) vs. WLC

12 × 45 min sessions delivered on 3 days over 4 weeks + at least 3 brief and one longer daily homework

Pre-training, post-training

ERSQ; PANAS

Statistically significant post-training increase in ERSQ scores and near-significant increase in positive affect scores

Bolier et al., 2014 [62] (Moderate-Low)

366

Allied health professionals (nurses, surgery assistants, physiotherapists, radiotherapists) (The Netherlands)

Cluster RCT

Web-based psychoeducation vs. Nil training

4 to 8 weeks

Pre-training, 3 months, 6 months

MHC-SF global score + subscales; WHO-5 Well-being Scale; BSI depression and anxiety subscales

All measures except BSI depression improved post-training, 3 months and 6 months follow-up for both groups. Significant improvement in MHC-SF global and psychological well-being subscales for training group only. Very low uptake and compliance

Brinkborg et al., 2011 [63] (High)

106

Social workers (Sweden)

RCT

Psychoeducational stress management and cognitive therapy (ACT-SMI) in high stress (PSS ≥ 25) vs. ACT-SMI in low stress (PSS ≤ 24) vs. high-stress WLC vs. low-stress WLC

4 × 3 h biweekly group sessions + homework (physical exercise, mindfulness)

Pre-training, post-training

PSS; MBI global, EE, DP, PA subscales; GHQ; Pbse

Significant reductions in all measures except Pbse for all ACT-SMI participants compared with WLC. High stress groups: significant reductions in PSS, MBI. Low stress groups: significant reductions in PSS, MBI global + PA subscale only

Brondolo et al., 2017 [64] (Moderate-Low)

257

ME’s, investigators, autopsy technicians, clerics/administrators, laboratory workers, clergy, legal staff, and facilities managers (USA)

Prospective cohort study

Web-based psychoeducation

3 modules × 16 classes × 5-7 min each, mean completion = 10.69 classes (SD = 7.74, range 1-21)

3 months and immediately pre-training, 1 month post-training

BDI; PDS

Of the 76 participants who completed at least 8 classes, post-training BDI scores were significantly lower than baseline or pre-training values, no changes in PDS values. Unadjusted M and SD values not reported in the text but provided by authors.

Carleton et al., 2018 [38] (Moderate-Low)

133

Police officers (Canada)

Prospective cohort study

Psychoeducational resilience promotion, stress management, coping skill building (R2MR)

4-h group seminar

Pre-training, 6 months, 12 months

BRS; DASS subscales; PCL; AUDIT

No statistically significant changes in mental health or resilience post-training or at follow-up, but small significant post-training reductions in stigma

Cheng et al., 2015 [65] (Moderate-High)

102

Hospital workers (physicians, nurses, physiotherapists, and occupational therapists) (Hong Kong)

RCT

Emotion regulation

Gratitude journal (2 weekly entries × 4 weeks) vs. Hassle journal vs. Nil treatment

Pre-training, post-training, 3 months

CES-D, PSS

Significant post-training reductions for the gratitude group only, further improved (CES-D) or maintained (PSS) at follow-up.

M and SD values extracted from reported regression analyses, author contacted for raw data

Chongruksa et al., 2012 [66] (Moderate-High)

42

Police officers (Thailand)

Cluster RCT

Multimodal psychoeducation and counseling vs. Mental health psychoeducation control

1.5–2 h/week × 12 weeks for both groups

Pre-training, mid-training, post-training, 1 month

BDI; GHQ global score + subscales; SCL-90 global score + subscales

Significant reductions in all measures mid- and post-training for the multimodal group only, and increased scores at 1-month follow-up

Christopher et al., 2016 [67] (Low)

43

Police officers (USA)

Prospective cohort study

Mindfulness-based resilience promotion

2 h × 8 weeks + 6 h final lesson + daily homework (20 h total)

Pre-training, mid-training, post-training

BRS; OLBI; PSQ; PSS; PROMIS Global Mental Health Subscale; cortisol AUC

Significant post-training improvements on all measures, and significant increase in cortisol AUC predicted by change in PROMIS mental health score

Christopher et al., 2018 [68] (Moderate-Low)

61

Police officers (USA)

RCT

Mindfulness-based resilience promotion vs. Nil training

2-h sessions × 8 weeks + 6-h session (20 h total)

Pre-training, post-training, 3 months

PROMIS subscales; Concise Health Risk Tracking Scale (suicidal ideation); PSQ; OLBI; CDRS; AUC cortisol

Significant post-training improvement in burnout and organizational stress only. Significant post-training reduction in cortisol AUC in males only. No differences at follow-up

Craigie et al., 2016 [69] (Moderate-High)

20

Nurses (Australia)

Prospective cohort study

Mindfulness-based resilience promotion

12 h total + daily mindfulness homework practice

Pre-training, post-training, 1 month

DASS subscales; ProQoL subscales; STAI; CDRS

Significant post-training reductions in DASS depression, ProQoL burnout, and STAI, only the latter two remained significant at follow-up. Significant improvements in DASS Stress and ProQoL compassion satisfaction from pre-training to follow-up

Daigle et al., 2018 [70] (Moderate-Low)

70

Nurses (Canada)

RCT

Mindfulness-based stress management vs. WLC

2.5 h × 8 weeks + full day retreat + recommended 45 min daily practice

Pre-training, post-training

POMS-TA

Significantly reduced POMS-TA post-training

Duarte et al., 2017 [71] (Low)*

48

Oncology nurses (Portugal)

Prospective cohort study

Mindfulness-based stress management

2-h group sessions × 6 weeks + 15 min daily homework

Post-training

DASS subscales; ProQoL BO, CF subscales, SLS

Significant post-training reductions in DASS Stress, ProQoL, and SLS. Direct effects of regression analyses reported only, author contacted for M and SD values

Duchemin et al., 2015 [72] (Moderate-Low)*

32

SICU personnel (USA)

RCT

Multimodal mindfulness-based intervention vs. WLC

9 × 1 h weekly sessions + recommended 20 min daily practice

Pre-training, post-training

PSS, DASS stress subscale, MBI EE, DP and PA subscales, ProQoL CS, BO STS subscales, self-report work stress

Significant post-training reduction in DASS stress and proportion of participants with high (> 26) EE scores.

M and SDs for primary outcome measures not provided, authors contacted.

Flarity et al., 2013 [73] (Moderate-Low)

59

Nurses (USA)

Prospective cohort study

Psychoeducational resilience promotion

4-h group seminar

Pre-training, post-training

ProQoL CS, BO, STS subscales

Significant post-training improvements in all subscale scores and proportion in high/low cut-off ranges

Hersch et al., 2016 [74] (Moderate-Low)

104

Nurses (USA)

RCT

Web-based stress management (BREATHE) vs. WLC

7 online modules (average time = 43 min)

Pre-training, 3 months post-training

Nursing Stress Scale; Symptoms of Distress (emotional symptoms subscale); Coping with Stress Scale

Significant post-training improvement in Nursing Stress Scale only. Low rates of participation

Joyce et al., 2018 [75] (Low)

29

Firefighters (Australia)

Prospective cohort study

Web-based, mindfulness-based resilience promotion (RAW)

6 × 20–25 min sessions + optional practice

Pre-training, post-training

CDRS; CFQ; AAQ-II

Mean increase in resilience and reduction in cognitive fusion, psychological inflexibility, and avoidance, but not statistically significant

Joyce et al., 2019 [76] (Moderate-High)

143

Primary Fire and Rescue and Hazmat (Australia)

Cluster RCT

Web-based, mindfulness-based resilience promotion (RAW) vs. Healthy Living Program (control)

6 × 20–25 min sessions + optional practice vs. 6 × 20 min modules

Pre-training, 6 weeks and 6 months post-training

CDRS; BRS; FMI; AAQ-II; SCS; LOT-R; COPE active coping, emotional support, instrumental support subscales; LET

Significantly higher resilience and active coping in RAW participants at 6 months follow-up compared with control but coping not sustained at follow-up. Improved mindfulness sustained in full but not partial program completers. Authors contacted for CDRS and BRS SD values.

Larijani et al., 2018 [77] (Low)*

126

Red Crescent Healthcare Centers (Iran)

Cluster RCT

Resilience promotion vs. Nil training

No description

Pre-training, post-training

GHQ physical symptoms, anxiety, social dysfunction, and depression subscales

Post-training improvements in physical symptoms, anxiety, and social dysfunction in experimental group only.

Ranked data not useable for meta-analyses, authors contacted for unadjusted M and SD values.

Lin et al., 2019 [78] (Moderate-Low)

90

Nurses (China)

RCT

Multimodal mindfulness-based cognitive therapy vs. WLC

8 × 2 h weekly group mindfulness sessions + recommended practice vs. nil

Pre-training, post-training, 3 months

PSS; PANAS; CDRS

Significant post-training improvements in perceived stress, positive affect, and negative affect maintained at follow up, improved resilience at follow-up compared with baseline

McCraty et al., 2009 [79] (Moderate-High)

75

Correctional officers (USA)

RCT

Psycho-educational and physiological stress management with HRV-BF (Power to Change Performance) vs. WLC

2 days + 3mons recommended practice at work

Pre-training, 3 months post-training

Salivary cortisol and DHEA; BP; HRRest; HRV components (RMSSD, HF, LF, VLF, total power, LF/HF ratio); BSI subscales; POQA subscales

Significantly lower DHEA, BP, HR, anger and increased LF/HF HRV ratio post-training, no physiological changes, and increases in depressive symptoms in control group

McCraty & Atkinson, 2012 [80] (Moderate-Low)

59

Police officers (USA)

RCT

Psycho-educational and physiological resilience promotion stress management with HRV-BF (Coherence Advantage Program) vs. WLC

3 × 4 h sessions

Pre-training, post-training

POQA subscales; BP and IBI during critical incident scenarios (n = 23, 12 exp, 11 ctrl)

Depression declined by 13% among trained officers while it increased by 17% in the control group. Significantly greater decrease in IBI during the post-training scenario in experimental group only. Authors contacted for HR data (SDs) and POQA baseline scores

Mealer et al., 2014 [81] (Moderate-Low)*

27

ICU nurses (USA)

RCT

Multimodal psychoeducation, mindfulness-based practice, emotional regulation vs. Nil training

12 weeks total: 2-day workshop + 12 × 30 min weekly writing sessions + 15 min × 3/week mindfulness + 30–45min exercise × 3/week + 30–60 min counseling session

Pre-training, 1wk post-training

CDRS, PDS, HADS, MBI EE, DP, and PA subscales

Post-training reductions in depression symptoms in the experimental group. Both groups reported significant reductions in PTSD symptoms and improvements in resilience.

Molek-Winiarska & Żołnierczyk-Zreda, 2018 [82] (Moderate-High)

66

Miners (Poland)

RCT

Mindfulness-based stress management vs. Nil training

8-h sessions × 5 weeks (40 h total) + optional homework

Pre-training, 3 months post-training

GHQ global score and anxiety and depression subscales

Significant post-training reduction in anxiety and depression scores

Oliver & Meier, 2009 [83] (Moderate-High)

132

Small-town and rural police officers and sheriffs (USA)

Prospective cohort study

Stress management

8 h

Pre-training, post-training between 1-6mons, 7-12mons, or 13-18mons

Adult Manifest Anxiety Scale

No significant post-training reduction overall, but significant when analyzed according to post-test lag times (1-6mons, 7-12mons, 13-18mons)

Poulsen et al., 2015 [84] (Moderate-Low)

70

Radiation therapists and oncology nurses (Australia)

RCT

Stress management workshop vs. Written educational materials only

1 day

Pre-training, 6 weeks post-training

Recovery experiences questionnaire global score and subscales

Workshop group global scores increased post-training, and 3 of 4 subscales were higher than the control group

Ramey et al., 2016 [85] (Moderate-Low)

38

Police officers (USA)

Prospective cohort study

Psycho-educational and physiological emotion regulation with HRV-BF

2 × 2 h sessions held 2–3 weeks apart + 3mons practicing skills in the field

Pre-training, 3 months and 6 months post-training, but only a single post-training value is reported

BP; PSS; Impact of Events Scale total stress, intrusive and avoidance subscale scores; Response to Stressful Experience Scale; POQA subscales; on- and off-duty HR and HRV components (RMSSD, HF, LF, VLF, total power, LF/HF ratio), respiratory coherence on n = 26

Below threshold (p > 0.05) improvements to anger and resentment but increases in intrusive and avoidance scores. Significant post-training changes to sympathetic (LF) and parasympathetic (HF) contributors of HRV on both work and off days, increased RMSSD on off days, and significantly increased respiratory coherence. Coherence values not reported and requested from the authors

Ranta, 2009 [86] (Low)*

80

Police officers (India)

RCT

Multimodal psychophysiological stress management vs. Relaxation only

3 × 1 h sessions + brief home assignments vs. 1 × 1 h session

Pre-training, post-training

PSQ and CBQ global scores

Significant post-training improvements in both outcomes for the multimodal group only. SDs not provided, authors contacted.

Rø et al., 2010 [87] (Moderate-Low)

153

Nurses (Norway)

Prospective cohort study

Multimodal psychoeducational and psychophysiological retreat

5 days

Pre-training, 12 months post-training

MBI EE, DP, and PA subscales; proportion on sick leave; preceding year number of weeks on sick leave; adverse life events

Significant reductions in MBI EE and DP 12-months post-training. Number of adverse life events not reported, authors contacted

Rodrigues et al., 2018 [88] (Moderate-Low)

33

Nurses (USA)

Prospective cohort study

Stress management coping skill building

Single 90-min group session

Pre-training, 3 months post-training

MBI EE and DP subscales

Significant reduction in EE and DP 3 months post-training

Steinberg et al., 2016 [89] (Moderate-Low)*

32

SICU personnel (USA)

RCT

Mindfulness-based intervention

8 × 1 h weekly sessions + recommended 20-min practice × 5/week vs. Nil treatment

Pre-training, post-training

MBI EE, DP and PA subscales, ProQoL CS, BO, STS subscales, number of missed work days in past 2 months

Work satisfaction measures were significantly correlated with some mental health subscales, but were not reported or analyzed separately in the study.

M and SDs for primary outcome measures not provided, authors contacted.

Tveito & Eriksen, 2009 [90] (Moderate-Low)

40

Nursing home employees (Norway)

RCT

Multimodal stress management coping skill building (IHP) vs. WLC

15 × 1 h weekly sessions and workplace assessment + 9 months physical exercise

Pre-training, post-training, 12 months

General Health Status Inventory SF-36 Mental Health subscale; Demand/Control Model subscales; number of days on sick leave; job stress (undefined)

No significant differences between groups post-training or 1-year follow-up

Villani et al., 2013 [91] (Moderate-Low)

30

Oncology nurses (Italy)

RCT

Web-based stress management coping skill building (M-SIT) vs. Neutral stimuli control group

15-min video clips, 2×/week, 4 weeks (8 sessions, 2 h total)

Pre-training, post-training

STAI; COPE Active coping and Denial subscales

Significant post-training improvement on all measures for M-SIT group only

  1. AAQ-II Acceptance and Action Questionnaire II, ACT-SMI Acceptance and Commitment Therapy and Preventative Stress Management Intervention, AUC Area Under the Curve (Diurnal Cortisol), AUDIT Alcohol Use Disorders Identification Test, BAI Beck Anxiety Inventory, BDI Beck Depression Inventory, BO Burnout Subscale (ProQoL), BP blood pressure, BRS Brief Resilience Scale, BSI Brief Symptom Inventory, CBQ Coping Behaviour Questionnaire, CDRS Connor Davidson Resilience Scale, CES-D Center for Epidemiological Studies Depression Scale, CF Compassion Fatigue Subscale (ProQoL), CFQ Cognitive Fusion Questionnaire, COPE Brief Coping Orientation to Problems Experienced, CS Compassion Satisfaction Subscale (ProQoL), DASS Depression Anxiety Stress Scale-21, DHEA dehydroepiandrosterone-sulfate, DP Depersonalization Subscale (MBI), EE Emotional Exhaustion Subscale (MBI), ERSQ Emotion-Regulation Skills Questionnaire, EZ ERASE-Stress New Zealand, FMI Freiburg Mindfulness Inventory, GHQ General Health Questionnaire, HADS Hospital Anxiety and Depression Scale, HF high frequency, HPLP-II Health-Promoting Lifestyle Profile II, HR heart rate, HRAvg average heart rate, HRBase baseline resting heart rate, HRIndex maximum heart rate relative to resting heart rate, HRMax maximum heart rate, HRRec recovery time from maximum to resting heart rate, HRV heart rate variabilitym, HRV-BF heart rate variability biofeedback, IBI interbeat intervals, IHP Integrated Health Program, iTEC Integrative Training of Emotion-Regulation Competencies, LET Life Engagement Test, LF low frequency, LOT-R Life Orientation Test-Revised, M mean, MBI Maslach Burnout Inventory, ME medical examiner, METI Managing Emergencies and Traumatic Incidents Organizational Program, MHC-SF Mental Health Continuum Short Form, OLBI Oldenburg Burnout Inventory, PA Personal Accomplishment Subscale (MBI), PANAS Positive Affect Negative Affect Scale, Pbse Performance-based Self-esteem Scale, PCL Posttraumatic Checklist, PDS Posttraumatic Diagnostic Scale, POMS Profile of Mood States, POMS-TA POMS Tension-Anxiety Subscale, POQA Personal and Organizational Quality Assessment, PROMIS Patient Reported Outcomes Measurement Information System, ProQoL Professional Quality of Life Scale, PSQ Police Stress Questionnaire, PSS Perceived Stress Scale, RAW Resilience@Work, RCT randomized control trial, RMSSD root mean squared standard deviation, RS Resilience Scale, R2MR Road to Mental Readiness, SCL-90 Symptoms Checklist, SCS Self-Compassion Scale, SD Standard Deviation, SICU surgical intensive care unit, SLS Satisfaction with Life Scale, STAI State-Trait Anxiety Inventory, STS Secondary Traumatic Stress Subscale (ProQoL), TAU training as usual, VLF very low frequency, WLC waitlist control