Table 1 The detailed strategy and details of formula for search in databases

(A). MEDLINE

1. Lung Diseases [MeSH Terms]

2. Lung Diseases, Obstructive [MeSH Terms]

3. Pulmonary Disease, Chronic Obstructive [MeSH Terms]

4. Bronchial Diseases [MeSH Terms]

5. Emphysema [MeSH Terms]

6. Hypoxia [MeSH Terms]

7. Hypoxemia [MeSH Terms]

8. COPD [All Fields]

9. COAD [All Fields]

10. COBD [All Fields]

11. exercise induced-desaturation [Title/Abstract])

12. #1OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10

13. supplemental oxygen [Title/Abstract]

14. oxygen Inhalation Therapy [MeSH Terms]

15. oxygen supplementation [Title/Abstract]

16. oxygen supply [Title/Abstract]

17. Oxygen [MeSH Terms]

18. #13 OR #14 OR #15 OR #16 OR #17

19. exercise [MeSH Terms]

20. resistance Training [MeSH Terms]

21. exercise Therapy [MeSH Terms]

22. high-Intensity Interval Training [MeSH Terms]

23. physical Therapy Modalities [MeSH Terms]

24. physical Conditioning, Human [MeSH Terms]

25. rehabilitation [MeSH Terms]

26. #19 OR #20 OR #21 OR #22 OR #23 OR #24

27. randomized Controlled Trial [Title/Abstract]

28. trial [Title/Abstract]

29. randomized [Title/Abstract]

30. randomized [Title/Abstract]

31. randomly [Title/Abstract])

32. placebo [Title/Abstract]

33. #27 OR #28 OR #29 OR #30 OR #31 OR #32

34. Animals [Title/Abstract])

35. #33 NOT #34

36. #12 AND #18 AND #26 AND #35

(B). Embase

1. lung diseases

2. obstructive lung diseases

3. chronic obstructive pulmonary disease

4. bronchial diseases

5. emphysema

6. hypoxia

7. hypoxemia

8. COPD: ab

9. exercise induced-desaturation

10. #1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9

11. oxygen inhalation therapy

12. supplemental oxygen

13. oxygen supplementation

14. oxygen supply

15. #11 OR #12 OR #13 OR #14

16. exercise

17. resistance training

18. exercise therapy

19. interval training

20. physical therapy

21. rehabilitation

22. physical conditioning

23. exercise training

24. #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22 OR #23

25. randomized controlled trial

26. trial. ab

27. randomized. ab

28. randomly. ab

29. placebo

30. #25 OR #26 OR #27 OR #28 OR #29

31. animals. ab

32. #30 NOT #31

33. #10 AND #15 AND #24 AND #32

(C). Cochrane Central Register of Controlled Trials

1. MeSH descriptor: [Lung Diseases] explode all trees

2. MeSH descriptor: [Lung Diseases, Obstructive] explode all trees

3. MeSH descriptor: [Pulmonary Disease, Chronic Obstructive] explode all trees

4. MeSH descriptor: [Bronchial Diseases] explode all trees

5. MeSH descriptor: [Emphysema] explode all trees

6.7MeSH descriptor: [Hypoxia] explode all trees

7. Hypoxemia

8. COPD: ti,ab,kw OR COAD: ti,ab,kw OR COBD: ti,ab,kw OR exercise induced-desaturation: ti,ab,kw

9. #1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8

10. MeSH descriptor: [Oxygen Inhalation Therapy] explode all trees

11. supplemental oxygen

12. oxygen supplementation

13. oxygen supply

14. MeSH descriptor: [Oxygenators] explode all trees

15. #10 OR #11 OR #12 OR #13 OR #14

16. MeSH descriptor: [Exercise] explode all trees

17. MeSH descriptor: [Resistance Training] explode all trees

18. MeSH descriptor: [Exercise Therapy] explode all trees

19. MeSH descriptor: [High-Intensity Interval Training] explode all trees

20. MeSH descriptor: [Physical Therapy Modalities] explode all trees

21. MeSH descriptor: [Physical Conditioning, Human] explode all trees

22. Rehabilitation

23. #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22

24. Randomized Controlled Trial: pt OR trial: ti,ab,kw OR randomized: ti,ab,kw OR placebo: ti,ab,kw OR randomly: ti,ab,kw

25. animals

26. #24 NOT #25

27. #9 AND #15 AND #23 AND#26