Table 1 Summary of the included studies investigating the accuracy of hypoglycaemia detection of MID and NID
Device | Author, year | Country | Technique | Number of participants/paired measurements | Reference test | Type of diabetes | Setting | Threshold (mg/dl) | Mean age (years)/inclusion of children |
|---|---|---|---|---|---|---|---|---|---|
Eversense (Senseonics) | Christiansen, 2018 [19] | USA | MID | 74/16653 | Venous blood | T1DM: 67.8% T2DM: 29% | Hospital | 70 | 45.1/no |
G4 Platinum (Dexcom) | Steineck, 2019 [20] | Denmark | MID | 14/681 (venous) | Capillary and venous blood | T1DM: 100% | Hospital | 70 | 48/no |
G4 Platinum, regular algorithm (Dexcom) | Laffel, 2016 Study 1 [21] | USA | MID | 176/2922 | Venous and capillary blood | T1DM: 99% T2DM: 1% | Hospital | 80 | 11.4/yes |
G4 Platinum, Software 505 algorithm (Dexcom) | Laffel, 2016 Study 2 [21] | USA | MID | 79/2262 | Venous and capillary blood | T1DM: 100% | Home | 80 | 12.2/yes |
G4 Platinum (Dexcom) | Bailey, 2015 [22] | USA | MID | 51/2236 | Venous and capillary blood | T1DM: 86% T2DM: 14% | Hospital and home | 70 | 46.7/no |
G4 Platinum (Dexcom) | Nakamura, 2015 [23] | USA | MID | 68/9152 (venous) | Venous and capillary blood | T1DM: 83% T2DM: 17% | Home and hospital | 100, 90, 80, 70 | 42.2/no |
Guardian (Medtronic) | Bay, 2013 [24] | Denmark | MID | 72/1786 | Venous blood | T1DM: 100% | Hospital | 72, 54, 40 | no/55 |
Guardian (Medtronic) | Zijlstra, 2013 [25] | Germany | MID | 18/2317 | Capillary blood | T1DM: 100% | Hospital | 70 | 43/no |
Guardian (Medtronic) | Bode, 2004 [26] | USA | MID | 68/4435 | Capillary blood | T1DM: 100% | Home | 70 | 44/no |
CGMS Gold (Medtronic) | Lee, 2012 [27] | South Korea | MID | 12/122 | Capillary blood | DM: 41.67% Percentage of T1DM and T2DM not given | Hospital | 70 | 50.6/no |
CGMS Gold (Medtronic) | Adolfsson, 2009 [28] | Sweden | MID | 12/182 | Capillary blood | T1DM: 100% | During dive | 70 | 31/no |
CGMS (Medtronic) | Guerci, 2003 [29] | France | MID | 18/ng | Capillary blood | T1DM: 100% | Hospital | 55 | 40.4/no |
STS (Dexcom) | Rabiee, 2009 [30] | USA | MID | 19/1065 (capillary) | Capillary and venous blood | DM: 64.21% hereof 100% T2DM | Hospital | 55 | 61.6/no |
GlucoWatch (Cygnus) | Hathout, 2005 [31] | USA | NID | 30/327 | Capillary blood | T1DM: 100% | Home | 100, 90, 80, 70 | 9.96/yes |
Teledyne Sleep Sentry (Teledyne Avionics) | Johansen, 1986 [32] | Denmark | NID | 22/99 | Capillary blood | DM: 100% Percentage of T1DM and T2DM not given | Hospital | 54 | 37/no |