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Table 1 PICOS criteria for inclusion and exclusion of criteria

From: Effect of gut microbiota modulation on feeding tolerance of enterally fed critically ill adult patients: a systematic review

Parameter

Inclusion criteria

Exclusion criteria

Population

Adult tube-fed critically ill patients

Partial EN

Intervention

Supplementation with pre, pro, or synbiotics

 

Comparison

Placebo or nothing

 

Outcome

Enteral feed volume, Time to reach full enteral nutrition, the prevalence of feed intolerance and related GI complications (diarrhea, distention, high residual volume)

 

Study design

Randomized controlled trials

In vitro studies

  1. EN Enteral nutrition; GI Gastrointestinal