Parameter | Inclusion criteria | Exclusion criteria |
---|---|---|
Population | Adult tube-fed critically ill patients | Partial EN |
Intervention | Supplementation with pre, pro, or synbiotics | Â |
Comparison | Placebo or nothing | Â |
Outcome | Enteral feed volume, Time to reach full enteral nutrition, the prevalence of feed intolerance and related GI complications (diarrhea, distention, high residual volume) | Â |
Study design | Randomized controlled trials | In vitro studies |