From: Midazolam for sedation before procedures in adults and children: a systematic review update
Criteria | Description |
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Studies | • Randomized Controlled Trials in which midazolam was used for sedation before a procedure • No exclusions based on language or publication status |
Participants | • Adults or children • Studies that included participants undergoing dental procedures were excluded |
Interventions | • Studies that used midazolam by any route, at any dose or time, administered before a procedure • Studies that compared different drugs and different routes were excluded (e.g. intranasal midazolam plus intravenous sedative A versus intranasal sedative A plus intravenous midazolam; intravenous midazolam versus intranasal sedative A) |
Outcomes | Primary • Level of sedation on a sedation assessment scale • Anxiety • Incomplete procedures/difficulty performing procedures • Discomfort/pain Secondary • Anterograde amnesia • Over-sedation • Disinhibition or excitation • Quality of recovery • Allergic or anaphylactoid reactions • Sedation reversal • Tolerance of procedure or participant cooperation • Participant or proceduralist satisfaction |