Table 1 Outcome category, definition, and included inflammatory markers per category
Outcome category | Definition of outcome category | Inflammatory markers (per outcome category) |
|---|---|---|
Cells | Inflammation-related processes on cell level as a component of cellular immunity | Leukocytes  Eosinophils  Granulocytes  Lymphocytes  Macrophages  Monocytes  Neutrophils Dendritic cells |
Plasma molecules | Inflammation-related processes on plasma protein level as a component of humoral immunity | Acute-phase proteins  C-reactive protein (CRP)  Fibrinogen  Serum amyloid A |
Cytokines  Chemokines  Interferon-gamma (IFN-γ)  Interleukins (IL)  Lymphokines  Monokines  Tumor necrosis factor-alpha (TNF-α) | ||
Cell-free DNA | ||
Inflammasomes | ||
Intercellular adhesion molecule-1 | ||
Intracellular processes | Inflammation-related processes on intracellular level | Transcription factors  AP-1  NF-IL6  NF-kappa B Gene expression  Transcripts for proteins associated with inflammatory processes  Transcriptomics focusing on or revealing inflammatory processes |