Study characteristics | Inclusion criteria |
---|---|
Population | Children < 18 years of age with suspected invasive bacterial infection |
Index tests | Mid-regional proadrenomedullin |
Reference test | Quantitative PCR and/or culture of sterile site (blood, urine and/or CSF) specimens |
Outcomes | True and false positives, true and false negatives |
Study designs | All prospective, retrospective and randomised control studies that report measures of diagnostic accuracy of mid-regional pro-adrenomedullin in the diagnosis of IBI. |