Fig. 5

Statistical comparisons of screening burden. Each point is a McNemar’s odds ratio comparing EPPI-Reviewer and Abstrackr. Points to the left of center favor EPPI-Reviewer, and points to the right of center favor Abstrackr. Horizontal bars show 95% confidence intervals. Note that for dabigatran, in Task 2 (final inclusion), Abstrackr required all abstracts to be screened before reaching the last included study, while EPPI-Reviewer only required 70% of abstracts screened to identify all included studies. This resulted in a McNemar’s odds ratio of infinite value, hence the apparent ln (OR) of − 3 was created to represent this finding on the graph; the result was statistically significant in favor of EPPI-Reviewer