Potential predictors | Odds ratio (95% CI) | p value |
---|---|---|
Effect size (relative risk) | 0.43 | |
0–0.5 | 2.48 (0.61, 10.1) | |
0.5–1 | Ref | |
> 1 | 0.79 (0.32, 1.91) | |
Statistically significant | 1.50 (0.47, 4.84) | 0.50 |
Multicenter | 1.34 (0.68, 2.62) | 0.39 |
Medical domain | 0.11 | |
Medicine | 4.25 (0.82, 22.2) | |
Obstetric | 0.68 (0.06, 8.03) | |
Pediatrics | 0.99 (0.17, 5.71) | |
Surgery | Ref | |
Industry funding | 1.61 (0.71, 3.67) | 0.26 |
Peer review funding | 0.99 (0.38, 2.57) | 0.99 |
Random sequence | 1.58 (0.63, 3.93) | 0.33 |
Allocation concealment, clearly adequate (A) or not (BCD) | 0.53 (0.26, 1.08) | 0.08 |
Double-blind | 0.88 (0.21, 3.64) | 0.86 |
Analysis as randomized | 0.65 | |
Unclear | 0.60 (0.17, 2.09) | |
As treated | 0.57 (0.18, 1.80) | |
As randomized | Ref | |
Sample size (every 10 increase) | 1.012 (0.997, 1.027) | 0.12 |
Country | 0.84 | |
Canada/USA | 2.60 (0.11, 63.0) | |
Europe | 1.54 (0.06, 36.6) | |
Asia | Ref | |
Other | 2.42 (0.07, 84.7) |