Table 1 Summary of moderators
Moderator | Hypothesis | Rationale and evidence for moderators |
|---|---|---|
Age | Younger age is hypothesized to be associated with lower levels of and lower risk for sexual dysfunction, higher sexual satisfaction | Systematic review and community studies showed that younger age is associated with lower prevalence of sexual dysfunction [48,49,50] |
Gender | Male gender is hypothesized to be associated with lower levels of and lower risk for sexual dysfunction, higher levels of sexual satisfaction | Observational studies in clinical samples with OCD showed that females had higher prevalence of sexual dysfunctions than men [34] |
Married/Cohabitant status | Married/cohabitant status is hypothesized to be associated with lower levels of and lower risk for sexual dysfunction, higher sexual satisfaction | Married/cohabitant status was found to be associated with lower prevalence of sexual dysfunctions [50] |
OCD symptom severity | Higher OCD severity is hypothesized to be associated with lower levels of and lower risk for sexual dysfunction, higher sexual satisfaction | Systematic review showed that higher OCD was associated with worse outcomes in a variety of quality of life domains [5] |
Comorbid depressive disorders | Lower percentage of comorbid depressive disorders are hypothesized to be associated with lower levels of and lower risk for sexual dysfunction, higher sexual satisfaction | Observational studies in clinical and non-clinical samples showed that comorbid depressive disorders and/or or symptoms [34, 52] |
Comorbid anxiety disorders | Lower percentage of comorbid anxiety disorders are hypothesized to be associated with lower levels of and lower risk for sexual dysfunction, higher sexual satisfaction | Observational studies showed that anxiety disorders are associated with sexual dysfunctions and/or lower sexual satisfaction [53, 54] |
Concurrent psychiatric medication | Lack of concurrent psychiatric medication is hypothesized to be associated with lower levels of and lower risk for sexual dysfunction, higher sexual satisfaction | Longitudinal and cross-sectional studies showed that psychiatric medication, specifically antidepressants, are associated with higher levels and prevalence of sexual dysfunctions [36,37,38] |
Comorbid medical disease | Comorbid medical disease is hypothesized to be associated with lower levels of and lower risk for sexual dysfunction, higher sexual satisfaction | Systematic reviews showed that general medical disease is associated with a higher prevalence of sexual dysfunctions [54,55,56] |