Table 1 Respective roles of the commissioning and review teams

Identifying and liaising with experts in the areas of antenatal screening and VP throughout the review process

N/A

 • Preparing and supplying review brief, outlining:

  o Aims, background and key questions

  o Population, Intervention, Comparator and Outcomes (PICO) for each question

 • Critiquing the proposed review approach, including:

  o Commenting on draft versions of the review protocol

  o Providing and coordinating expert input

 • Providing the evidence summary reporting checklist and evidence summary template

Developing a formal review protocol to meet the review brief provided by the commissioning team, including developing the search strategy

Clarifying queries from the review team regarding the eligibility criteria

• Conducting literature searches

• Screening the search results against prespecified eligibility criteria and making final decisions with regard to the eligibility of studies for inclusion in the review

• Extracting data from relevant studies and assessing the quality of each study

 • Assisting the review team with making judgements as to whether the evidence identified met the UK NSC evidence criteria

 • Leading discussion of the draft review within the UK NSC reference group structures

Synthesising the data relating to each review question, including making a judgement as to whether the UK NSC’s screening criteria were met or not

Leading the 3-month public stakeholder consultation, including:

 • Hosting the consultation on the UK NSC website

 • Analysing the stakeholder input and coordinating appropriate responses and changes to the final product where required

Developing a full report meeting the requirements of the UK NSC’s evidence summary reporting checklist

Preparing the report of the review process for the UK NSC decision-making meeting

Supporting the commissioning team in responding to comments from the public stakeholder consultation