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Table 2 Results of AMSTAR-2

From: An overview of systematic reviews of complementary and alternative therapies for infantile colic

Author (date) CAM

1. Were PICO components listed?

2. Protocol reported? Any deviations justified?

3. Study design justified?

4. Comprehensive literature search?

5. Was study selection performed in duplicate?

6. Was data extraction performed in duplicate?

7. List of excluded studies? Were these justified?

8. Characteristics of studies provided in detail?

9. Risk of bias assessed?

10. Sources of funding of included studies?

11. Methods used to combine the findings of studies appropriate? Test on heterogeneity?

12. If meta-analysis performed was RoB accounted for?

13. Was RoB discussed in individual studies?

14. Was there discussion of any heterogeneity observed in the results?

15. If a quantitative synthesis, was publication bias investigated and discussed in relation to the results?

16. Reviewers’conflict of interests stated?

Confidence in the review

Multiple CAM therapies

 

 Perry [22]

Yes

PY

No

PY

PY

Yes

No

Yes

Yes

No

No MA

No MA

Yes

No

No MA

Yes

Low

 Bruyas-Bertholon [23]

No

No

No

No

No

No

No

PY

PY

No

No MA

No MA

No

No

No MA

No

CL

 Harb [24]

Yes

No

No

No

Yes

Yes

No

PY

Yes

No

Yes

Yes

Yes

No

Yes

Yes

CL

 Gutierrez-Castrellon [25]

Yes

No

No

No

No

No

No

No

No

No

No

No

Yes

No

Yes

No

CL

Manipulation therapies

 Dobson [26]

Yes

Yes

No

Yes

Yes

Yes

Yes

Yes

Yes

No

Yes

Yes

Yes

Noa

Yes

Yes

High

 Gleberzon [27]

No

No

No

PY

No

Yes

No

PY

No

No

No MA

No MA

Yes

No

No MA

No

CL

 Carnes [28]

No

PY

No

PY

Yes

Yes

No

PY

Yes

No

No

No

No

No

No

No

CL

Acupuncture

 

 Skejeie [29]

Yes

PY

No

Yes

Yes

Yes

No

Yes

Yes

No

Yes

Yes

Yes

Yes

No

Nod

Low

Herbal medicines

 

 Anheyer [30]

No

No

No

No

No

Yes

No

Yes

Yes

No

No MA

No MA

No

No

No MA

Yes

CL

Probiotics

 

 Sung [31]

Yes

No

No

No

Yes

Yes

Yes

PY

Yes

No

Yes

No

Yes

No

No

Yes

CL

 Anabrees [32]

Yes

PY

No

PY

No

Yes

No

Yes

Yes

No

Yes

No

Yes

Yes

No

Yes

Low

 Urbanska [33]

Yes

No

No

PY

No

No

No

PY

Yes

Yes

No

No

No

No

No

No

CL

 Xu [34]

No

No

No

PY

Yes

Yes

No

Yes

Yes

No

Yes

No

No

No

No

Yes

CL

 Schreck Bird [35]

Yes

No

No

No

Yes

No

No

Yes

Yes

No

No

No

No

No

No

No

CL

 Dryl [36]

Yes

No

No

No

No

No

No

PY

Yes

No

No

No

No

No

No

No

CL

 Sung [37]

Yes

PY

No

PYb

No

No

No

No

Yes

No

Yes

Yes

Yes

Yes

Yes

Noc

Low

  1. CL critically low, PY partial yes, MA meta-analysis, PICO participants, intervention, comparator, outcomes, RoB risk of bias
  2. Grey columns represent the critical domains (see Additional file 1)
  3. aToo few studies to perform a test of heterogeneity
  4. bNot fully searched and search conducted Dec 2014
  5. cConflict of interest occurred but no indication of how it was dealt with
  6. dAll included studies were by the author team but did not indicate how this was dealt with