Population | |
Source of population well described | |
Eligible population representative of the source of population | |
Participants represent eligible population | |
Selection/methods | |
Selection bias minimized | |
Reasonable variables selection | |
Acceptably low contamination | |
Confounding factors identified and controlled | |
Outcomes | |
Outcome measures and procedures reliable | |
Outcome measurements complete | |
All important outcomes assessed | |
Similar follow-up time in exposed and comparison groups | |
Follow-up time meaningful | |
Analyses | |
Study was sufficiently powered to detect an intervention (if any) | |
Multiple explanatory variables considered in the analysis | |
Analytical methods appropriate | |
Precision of association given or calculable and meaningful | |
Summary | |
Study results internally valid | |
Findings are generalizable to the source population |