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Table 3 Outcomes of acceptability, feasibility, and efficacy (randomized controlled trials)

From: Acceptability, feasibility, and efficacy of Internet cognitive behavioral therapy (iCBT) for pediatric obsessive-compulsive disorder: a systematic review

Reference

Measure

Pre-treatment

M (SD)

Post-treatment

M (SD)

Between groups

Significance (WL-CBT)

Between groups

Significance (iCBT-CBT)

Within group

Significance

PRE-POST

Between groups

Effect size

(d)

Follow-up

M (SD)

Comer et al. (USA) [30]

Efficacy

CY-BOCS

22.9 (4.1)

14.9 (7.3)

Not Applicable

p=n.s

Not Reported c

0.09

11.8 (9.5) b

ADIS-IV-C/P

(OCD CSR)

5.1 (0.8)

3.4 (1.2)

Not Applicable

p=n.s

Not Reported c

0.24

2.4 (2.6) b

CGI-S

4.9 (0.7)

3.2 (1.5)

Not Applicable

p=n.s

Not Reported c

-0.06

2.6 (2.5) b

CGAS

48.0 (8.0)

61.4 (12.0)

Not Applicable

p=n.s

Not Reported c

-0.06

66.6 (15.9) b

FAS

29.5 (7.8)

19.5 (9.7)

Not Applicable

p=n.s

Not Reported c

0.56

15.6 (14.2) b

Acceptability

CSQ-8

Not Applicable

Mother 28.6 (4.5)

Not Applicable

p=n.s.

Not Applicable

Not Applicable

Not Applicable

WAI

Not Applicable

Mother 223.5 (34.8)

Therapist 226.1 (32.9)

Not Applicable

p=n.s.

p=n.s.

Not Applicable

Not Applicable

Not Applicable

Feasibility

Treatment drop-out

Not Applicable

Dropout = 1

Not Applicable

Not Applicable

Not Applicable

Not Applicable

Not Applicable

Lenhard et al. (Sweden) [29, 33]

Efficacy

CY-BOCS

23.0 (4.3)

17.0 (6.3)

p<0.001

Not Applicable

Not Reported

0.69

14.2 (5.9) a

ChOCI-R child

24.5 (6.7)

20.0 (7.8)

p=0.014

Not Applicable

Not Reported

0.64

19.3 (8.3) a

ChOCI-R parent

24.4 (7.6)

19.3 (9.9)

p=0.012

Not Applicable

Not Reported

0.59

17.7 (8.7) a

CDI

4.7 (3.4)

4.6 (4.0)

p=n.s.

Not Applicable

Not Reported

-0.01

4.7 (4.2) a

SCAS parent

10.7 (5.8)

8.3 (5.9)

p=0.004

Not Applicable

Not Reported

0.67

8.4 (5.6) a

SCAS child

12.9 (6.4 )

11.4 (7.4)

p=n.s.

Not Applicable

Not Reported

0.27

10.4 ( 6.4) a

EWSAS child

14.8 (9.2)

12.8 (9.7)

p=n.s.

Not Applicable

Not Reported

0.27

10.7 (9.1) a

EWSAS parent

16.1 (8.6)

11.4 (8.5)

p<0.001

Not Applicable

Not Reported

0.43

11.1 (9.2) a

FAS

15.8 (11.3)

11.2 (9.2)

p=0.003

Not Applicable

Not Reported

0.54

10.6 (10.2) a

Acceptability

Self-made questionnaire

Not Applicable

46% of the patients were satisfied with internet- delivered format, 50% would have liked to meet a clinician

4% would have preferred face-to-face treatment

Patients’ treatment rating: 32% Very Good, 32% Good

36% Ok, 0% Bad

Not Applicable

Not Applicable

Not Applicable

Not Applicable

Not Applicable

Feasibility

Treatment drop-out

Not Applicable

8.5/12 chapters completed (2.9)

Dropout = 1

Not Applicable

Not Applicable

Not Applicable

 

Not Applicable

Storch et al. (USA) [34]

Efficacy

CY-BOCS

25.4 (3.6)

11.1 (10.5)

p<0.001

Not Applicable

Not Reported

1.36

11.3 (9.4) a

COIS Parent

42.8 (23.4)

16.8 (24.5)

p=0.005

Not Applicable

Not Reported

0.99

Not Reported

COIS child

38.8 (24.1)

16.1 (19.0)

p=0.03

Not Applicable

Not Reported

0.46

Not Reported

CGI-S

3.8 (0.9)

1.6 (1.8)

p<0.001

Not Applicable

Not Reported

1.48

1.4 (1.3) a

CGI-I

Not Applicable

13/16 participants (81%) responder (a ≥30% reduction in CY-BOCS score and a CGI-I score of 1 or 2)

p<0.001

Not Applicable

Not Reported

Not Applicable

Not Reported

CDI

8.9 (6.7)

7.5 (8.0)

p=n.s.

Not Applicable

Not Reported

0.43

Not Reported

MASC

39.9 (14.8)

33.4 (14.8)

p=n.s.

Not Applicable

Not Reported

0.46

Not Reported

FAS

25.7 (8.6)

16.1 (13.9)

p=0.003

Not Applicable

Not Reported

0.37

Not Reported

Acceptability

PWA

Not Applicable

19.4 (1.3)

Parents’ Satisfaction

Not Applicable

Not Applicable

Not applicable

Not applicable

Not Applicable

Feasibility

Treatment drop-out

Not Applicable

Dropout = 2

Not Applicable

Not Applicable

Not applicable

Not applicable

Not Applicable