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Table 1 Research question development according to the PICO strategy

From: Auriculotherapy to control chemotherapy-induced nausea and vomiting in patients with cancer: protocol of a systematic review

PICO Components
Review question What is the auriculotherapy effect in controlling the nausea and vomiting induced by chemotherapy in patients with cancer in comparison to the Sham auriculotherapy, to the routine treatment, or other non-pharmacological interventions?
Population Patients with cancer undergoing chemotherapeutic antineoplastic treatment
Intervention Auriculotherapy with seeds (mustard/Vaccaria), metallic points, magnetic points, plastic points (crystals) needles (semi-permanent and systemic), stiper, radionic crystals, electroacupuncture, chromotherapy, laser therapy, and electromagnetic stimulation (hai hua)
Comparator Sham auriculotherapy, routine treatment with antiemetic drugs, and other non-pharmacological interventions
Outcomes Chemotherapy-induced nausea and vomiting control (acute, delayed, anticipated) and adverse events originated from the uses of auriculotherapy as a CINV treatment for patients with cancer