Stage 1: initial systematic mapping review of prognostic research
|| A descriptive map of prognostic research for lung cancer survival based on the assessment of titles and abstracts only. ● Classification of relevant reviews and meta-analysis according to PROGRESS research themes 1–4, lung cancer type, number and type of prognostic factors investigated, and publication type. ● Identification of all prognostic factors, from which a comprehensive coding scheme was developed. ● Identification of prognostic factors deemed to be potentially modifiable (reviewed by two independent public health and clinical stakeholders). |
Stage 2: overview of systematic reviews of prognostic factor research
|| A more in-depth review of a subset of systematic reviews focusing on prognostic factor research (PROGRESS research theme 2) based on the assessment of full text publications. ● Summary of key data from included reviews. ● Coding of reviews according to the prognostic factors they addressed. ● Summary of all prognostic factors investigated by each review, including whether or not they were significantly associated with survival†, and the direction of the impact.
Stage 3: in-depth evaluation of potentially modifiable factors
|| A more in-depth evaluation of the results of included reviews reporting modifiable factors. ● Summary of the magnitude of the effect of modifiable prognostic factors (where possible). |