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Table 1 Showing the various eGFR equations used in CKD population

From: Accurate GFR in obesity—protocol for a systematic review

Equation name

Equation

Mean BMI in derivation cohort (SD)

20CKD-EPI creatinine

eGFR = 141 ×min(Scr/κ, 1)α × max(Scr/κ, 1)−1.209 X 0.993Age × 1.018 [if female] × 1.159 [if black] where:

28 (6)

Scr is serum creatinine in μmol/L,

κ is 61.9 for females and 79.6 for males,

α is − 0.329 for females and − 0.411 for males,

min indicates the minimum of Scr/κ or 1,

and max indicates the maximum of Scr/κ or 1.

The unit of results is ml/min/1.73 m2

34CKD-EPI Cystatin C

eGFR =  133 ×min(Scys/0.8, 1)−0.499 × max(Scys/0.8, 1)−1.328 × 0.996Age0.932 [If female]

28 (6)

The unit of results is ml/min/1.73 m2

42CKD-EPI BTP*

eGFR =  55 *BTP−0.695 × 0.998Age × 0.899 [If female]

30.1 (6.4)

The unit of results is ml/min/1.73 m2

25Cockcroft-Gault

Creatinine clearance (eGFR) = ((1.23 [If male], 1.04 [If female) × Weight in kg × (140 − age))/Creatinine

Not reported

The unit of results is ml/min

34CKD-EPI creatinine-cystatin C

eGFR =  135 ×min(SCr/κ, 1)α ×max(SCr/κ, 1)−0.601 × min(Scys/0.8, 1)−0.375 × max(Scys/0.8, 1)−0.711 × 0.995Age × 0.969 [if female] × 1.08 [if black]

28 (6)

κ = 61.9 (females) or 79.6 (males)

α = − 0.248 (females) or − 0.207 (males)

min(SCr/κ or 1) = indicates the minimum of SCr/κ or 1

max(SCr/κ or 1) = indicates the maximum of SCr/κ or 1

min(Scys/0.8, 1) = indicates the minimum of Scys/0.8, 1

max(Scys/0.8, 1) = indicates the maximum of Scys/0.8, 1

The unit of results is ml/min/1.73 m2

53Jelliffe

Creatinine clearance (eGFR) = 98–16×(age − 20/20)/(Creatinine/88.4). For females, multiply by 0.9

Not mentioned

The unit of results is ml/min/1.73 m2

19Salazar-Corcoran

For males creatinine clearance (eGFR) = (137 − age)× ((0.287 ×weight in kg) + (12.1×height in meters2))/51×Creatinine

Developed for obesity but not in common use

For females creatinine clearance (eGFR) = (146 − age)× ((0.287 ×weight in kg) + (9.74 ×height in meters2))/60×Creatinine

The unit of results is ml/min