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Table 1 Study data collection

From: Mesenchymal stem cells for sensorineural hearing loss: protocol for a systematic review of preclinical studies

Study characteristic

Specific items

Study identifiers

Title, authors, journal, publication year, county of publication, and sponsorship

Study design

Number of animals assigned to each experimental and control group and method of SNHL induction

Animal model characteristics

Animal species, gender, strain, age, method of SNHL induction, and immune status

Intervention characteristics

Source of MSCs, MSC identifiers including plastic adherence, positive/negative markers, differentiation, cell expansion media, passage number, cell dose, method of delivery, timing relative to SNHL induction, and frequency of MSC administration

Outcome measures

Method of assessing hearing outcome and timing of data collection relative to SNHL induction

Other

Long-term outcomes, type of control, MSC side effects (animal survival)