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Table 1 Characteristics and variables to be extracted from the included articles

From: Evaluation of the impact of single-nucleotide polymorphisms on treatment response, survival and toxicity with cytarabine and anthracyclines in patients with acute myeloid leukaemia: a systematic review protocol

Characteristics

Variables

Study characteristics

Reference; study type; country; context

Population

Participants number; amount of groups; age in years; eligibility criteria; sample selection method; treatment performed; type of AML

Exposures

SNP; DNA localization; related gene; altered nitrogen bases

Outcomes

Toxicity (degree and type); disease-free and global survival; response to treatment

Results

Description of the data; confidence intervals and p values of the study, survival and treatment response in randomized clinical trials; assessment of outcomes in cohort and case-control studies