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Table 2 Grades of evidence according to GRADE and their definitions

From: Screening for periodontal diseases by non-dental health professionals: a protocol for a systematic review and overview of reviews

Grade

Definition

High

We are very confident that the true effect lies close to that of the estimate of the effect.

Moderate

We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.

Low

Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect.

Very Low

We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect.