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Table 5 Secondary outcomes of interest from studies

From: A systematic review of enteric dysbiosis in chronic fatigue syndrome/myalgic encephalomyelitis

Author Secondary outcome measure (s) Result (s)
GI symptoms
 Mandarono et al. Unknown tool Gastrointestinal symptoms reported in 65% CFS/ME vs. 35% HC
Symptom severity
 Mandarano et al. Bell’s disability scale Higher reported severity of CFS/ME-related symptoms in CFS/ME vs. HC
QoL
 Shukla et al. MFI Higher scores in CFS/ME vs. HC (p < 0.05) for general and physical fatigue, reduced activity and motivation and mental fatigue
Psychological symptoms
 Rao et al. BAI Improved anxiety scores in the treatment group (p = 0.01)
 Shukla et al. POMS Higher scores for fatigue, confusion and total mood disturbance in CFS/ME vs. HC (p < 0.05)
Lower scores for vigour in CFS/ME vs. HC (p < 0.05)
  1. GI gastrointestinal, IBS inflammatory bowel syndrome, CFS/ME chronic fatigue syndrome/myalgic encephalomyelitis, HC healthy control, QoL quality of life, MFI Multidimensional Fatigue Inventory, BAI Beck’s Anxiety Inventory, POMS Profile of Mood States