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Table 7 Summary of mortality outcome for device, dialysis, and glucose control interventions for a significant difference in mortality

From: Anesthesia interventions that alter perioperative mortality: a scoping review

First author, year Type of surgery Anesthesia-related intervention theme Intervention/ comparison details Perioperative phase, duration of intervention Impact on mortality* (outcome definition, timing)
Durmaz, 2003 Cardiac, 44 Dialysis Prophylactic preoperative hemodialysis for patients undergoing CABG surgery with underlying renal failure.
Usual care: received postoperative dialysis if there was a 50% increase in serum creatinine from baseline or patient exhibited inadequate urine output less than 400 mL for 24 h despite correction of hemodynamic status and diuretic therapy.
Preoperative, postoperative
Every day for a time period
Decreased mortality (in-hospital mortality, NR)
Thielman, 2013 Cardiac, 329 Medical device Remote ischemic preconditioning took place after induction of anesthesia and before skin incision. Three cycles of 5 min ischemia, achieved by inflation of a blood pressure cuff to 200 mmHg, followed by 5 min reperfusion while the cuff was deflated were applied to the upper left arm.
No treatment
Intraoperative
Once
Decreased mortality (all-cause 30-day mortality, secondary outcome)
Qiu, 2009 Cardiac, 221 Medical Device “The IABP catheter used was 8 F 34 ml balloon Percor STAT-DL Catheter (Datascope Corp, Fairfield, NJ) connected to a Datascope portable computerized console (Datascope), placed using percutaneous insertion technique via the femoral artery.”
“Preoperative insertion was normally performed in the anesthesia preparation room in the operating room (OR) prior to induction of anesthesia.”
Intraoperative
During most of the intraoperative period
Decreased mortality (in-hospital, NR)
van den Berghe, 2001 NR, 1548 Glucose control Intensive insulin therapy (target blood glucose of 80–110 mg/dL) in mechanically ventilated ICU patients
Usual care: a continuous infusion of insulin (50 IU in 50 mL 0.9% NaCl) was started only if the blood glucose level exceeded 215 mg/dL, with the infusion adjusted to maintain the level between 180 and 200 mg/dL.
Postoperative
In the intervention group, the intensive treatment approach was followed until the patient was discharged from the intensive care unit, at which point the conventional approach was adopted.
Decreased mortality (death during intensive care, primary outcome)
Decreased mortality (in-hospital mortality, secondary outcome)
  1. Anesthesia-related intervention refers to interventions provided in the perioperative period that was or could be performed, organized, or initiated by a healthcare professional with specific training in anesthesia
  2. ND no significant change, NR not reported