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Table 4 Comparison of AGREE II mean domain scores to examine change in overall quality

From: The quality of clinical practice guidelines for management of pediatric type 2 diabetes mellitus: a systematic review using the AGREE II instrument

AGREE II Domain Earlier version
Mean (SD)
Latest version
Mean (SD)
p value
Scope and Purpose 54.43 13.84 71.14 19.66 0.005*
Stakeholder Involvement 43.00 13.98 65.57 23.80 0.01*
Rigour of Development 39.86 12.29 52.43 24.52 0.20
Clarity of Presentation 66.71 17.40 77.43 19.35 0.11
Applicability 38.14 14.22 57.71 28.73 0.13
Editorial Independence 30.29 34.96 46.71 34.44 0.13
  1. *p < 0.05
  2. Note: Mean domain scores of CPGs from earlier and most recent CPGs available – American Diabetes Association (2000 and 2016), Brazil Diabetes Society (2014–2015 and 2015–2016), Diabetes Canada (2013 and 2018), Italian Diabetes Society (2007 and 2014), Singapore Ministry of Health (2006 and 2014), Society for Endocrinology, Metabolism and Diabetes of South Africa (2012 and 2017) and the International Society for Pediatric and Adolescent Diabetes (2009 and 2014)