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Table 1 PICO (population, intervention, control, and outcomes)

From: Evidence-based guidelines for physiotherapy management of patients with multiple myeloma: study protocol

Review question

What are the available evidence for the following:

- Safely mobilizing patients with multiple myeloma in an acute care setting

- Effective pain management in patients with multiple myeloma

- Physiotherapy (PT) management in patients with multiple myeloma receiving chemotherapy

- PT management in patients with multiple myeloma receiving radiation

- PT management in patients with multiple myeloma receiving a stem cell transplantation

- Management of fatigue and muscle weakness in patients with multiple myeloma

Population

Multiple myeloma or myeloma or plasma cell myeloma

Intervention

Physiotherapy or physical therapy, ambulation, mobilization, mobility, functional mobility training, exercise, strength training, endurance training, cardio-pulmonary exercise, aerobics exercise, anaerobic exercise, high-intensity exercise, low-intensity exercise, home-based exercise, multi-modal exercise, flexibility exercise, physical activity, pain management, and fatigue management

Comparator

Stated interventions compared with placebo or no interventions

Outcomes

All possible outcomes