Fig. 2From: Blood pressure reduction and clinical outcomes with angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers: protocol for a systematic review and meta-regression analysisSchema illustrating calculation of mean between-group difference in blood pressure. Hypothetical data are presented. In this example, the mean between-group difference in blood pressure would be (195–185) − (195–170) = 10–25 = − 15 mmHg. That is, the intervention drug reduced blood pressure, on average, by 15 mmHg more than the control drug (placebo or active comparator)Back to article page