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Table 2 Defined search strategy for the extraction of pertinent studies from multiple databases

From: Challenges of pain management in neurologically injured patients: systematic review protocol of analgesia and sedation strategies for early recovery from neurointensive care

EMBASE search
strategy search = ____
1. (Neuro$ ICU or Neuro$ Intensive Care or Neurocritical care or intensive care or critical care or ICU).mp. or Intensive care units/ [mp = title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms]
2. (Brain Injury or TBI or neuro$ trauma or neuro$ injury or cerebral injury or spin$ injur$).mp. or Spinal Cord Injuries/ or Brain Injuries/[mp = title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms]
3. (Stroke or Intracranial hemorrhage or intracranial hemorrhage or Subarachnoid hemorrhage or Subarachnoid hemorrhage or CVA or ischemic stroke or ischaemic stroke or Cerebral clot or Cerebral thrombosis).mp. or Nervous system diseases/ or Brain neoplasms.mp. or Cerebrovascular Disorders/ or Cerebral Hemorrhage/ or Cerebral Infarction/ or spinal diseases/ [mp = title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms]
4. ((((Cranial and surg$) or Cranial) and opera$) or Craniotomy).mp. or Neurosurgical procedures/ [mp = title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms]
5. (((Spin$ and surgery) or Spin$) and opera$).mp. [mp = title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms]
6. (((liberation or ABCDE$ or Awakening) and breathing coordination) or Delirium monitor$).mp. or Delirium/ or exercise.mp. or mobility.mp. or animation.mp. or analgesia.mp. or Analgesia/ or pain management.mp. or Pain Management/ or sedation.mp. or assessment.mp. or neuro$ exam.mp. or challenge$.mp. or family.mp. or Family/ [mp = title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms]
7. 2 or 3 or 4 or 5
8. 1 and 6 and 7
9. limit 8 to (human and english language and yr. = “1992 -Current”)
Medline (PubMed) search
strategy search = ____
1. (Neuro* ICU or Neuro* Intensive Care or Neurocritical care or intensive care or critical care or ICU).mp. or Intensive care units/[mp = title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms]
2. (Brain Injury or neuro* trauma or neuro* injury or cerebral injury or spin* injur*).mp. or Spinal Cord Injuries/ or Brain Injuries/ [mp = title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms]
3. (Stroke or Intracranial hemorrhage or intracranial hemorrhage or Subarachnoid hemorrhage or Subarachnoid hemorrhage or CVA or ischemic stroke or ischaemic stroke or Cerebral clot or Cerebral thrombosis).mp. or Nervous system diseases/ or Brain neoplasms.mp. or Cerebrovascular Disorders/ or Cerebral Hemorrhage/ or Cerebral Infarction/ or spinal diseases/ [mp = title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms]
4. ((((Cranial and surg*) or Cranial) and opera*) or Craniotomy).mp. or Neurosurgical procedures/ [mp = title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms]
5. (((Spin* and surgery) or Spin*) and opera*).mp. [mp = title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms]
6. (((liberation or ABCDE* or Awakening) and breathing coordination) or Delirium monitor*).mp. or Delirium/ or exercise.mp. or mobility.mp. or animation.mp. or analgesia.mp. or Analgesia/ or pain management.mp. or Pain Management/ or sedation.mp. or assessment.mp. or neuro* exam.mp. or challenge*.mp. or family.mp. or Family/ [mp = title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms]
“term”/=Emtree or MeSH term 7. 2 or 3 or 4 or 5
8. 1 and 6 and 7
9. limit 8 to (human and english language and yr. = “1992 -Current”)
Cochrane Library search
strategy search = ____
1. Search title, abstract, keywords: ABCDEF
2. Search title, abstract, keywords: ABCDE
3. Search title, abstract, keywords: Neurointensive
4. Search title, abstract, keywords: ICU
5. Search title, abstract, keywords: Intensive Care
World Health Organization (WHO) International Clinical Trials Registry Platform Search Strategy search = ____ Advanced Search:
[‘In the title’] ABCDE OR ABCDEF OR intensive* OR ICU OR critical care OR Neurocritical care OR intensive care
AND
[‘In the Intervention’] analgesia OR pain OR opioid OR sedation OR mobility OR weaning OR animation OR bundle OR family
Clinical Trials Registry (through National Institute for Health) search strategy
search = ____
Advanced Search: ‘other terms’:
(ABCDE OR ABCDEF OR intensive* OR ICU OR critical care OR Neurocritical care OR intensive care) AND (analgesia OR pain OR opioid OR sedation OR mobility OR weaning OR animation OR bundle OR family)