Table 1 Variables that will be extracted from non-Cochrane registration records
Protocol section | Variables |
|---|---|
Title, objectives | Focus of review |
Common ICD-10 code | |
Number of included studies | |
Total number of participants | |
Type of interventions | |
Meta-analysis included | |
Network meta-analysis included | |
Economic evaluation included | |
Use of terms “systematic reviews” or “meta-analysis” in title of abstract | |
SR registration (e.g., PROSPERO) mentioned | |
SR protocol mentioned | |
Reporting guideline (e.g., PRISMA) mentioned | |
Cochrane methods used | |
Eligibility criteria | Based on study design |
Based on publication status | |
Based on language of report | |
Search methods | Number of databases searched |
Years of coverage reported | |
Search terms reported | |
Trial registry (e.g., ClinicalTrials.gov) searched | |
Number of other sources searches | |
Other sources searched | |
Screening, extraction, and risk of bias assessment methods | Screening method |
Data extraction method | |
Study risk of bias/quality formally assessed | |
Study risk of bias/quality assessment method | |
Study risk of bias/quality assessment tool used | |
Study risk of bias/quality assessment incorporated into meta-analysis | |
Included/excluded studies and participants | Review flow reported |
Reason for exclusion of full-text articles reported | |
Gray literature (e.g., conference abstracts) included | |
Outcomes | Number of outcomes stated |
Primary outcome stated | |
Type of primary outcome | |
Statistical significance of intervention | |
Direction of the effect | |
Statistical methods | Meta-analysis performed |
Meta-analysis model used | |
Statistical heterogeneity investigated | |
Heterogeneity statistic inappropriately guided choice of meta-analysis model (e.g., random effects model selected if I2 > 50%) investigated | |
Possibility of publication bias discussed/considered in results, discussion, or conclusion | |
Subgroup analysis performed | |
Sensitivity analysis performed | |
Meta-regression performed | |
Network meta-analysis performed | |
Limitations, conclusions, COIs, and funding | GRADE assessment reported in a summary of findings table or text |
Limitations reported | |
Study risk of bias/quality/limitations incorporated into therapeutic SR abstract conclusions | |
COIs reported | |
Source of funding of the SR |