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Table 3 Limitations in individual studies with respect to study design and data collection

From: A systematic review of neonatal treatment intensity scores and their potential application in low-resource setting hospitals for predicting mortality, morbidity and estimating resource use

Study Study type* Participants Outcome(s) Predictors§ Sample size|| Missing data
Georgieff,1989 [40] - - + + + ?
Gray,1992 [19] - - + + ? +
Davies,1995 [33] + + + + + ?
Eriksson,2002 [34] - - + + + +
Zupancic,2002 [35] - + ? + + ?
Mendes,2006 [36] - - + + + +
Rojas,2011 [37] - - + + + ?
Oygur,2012 [38] + - + + + -
Shah,2015 [32] + - + + ? +
Wu,2015 [39] + - + + + ?
  1. + Limitation present
  2. - No limitation
  3. ? Not reported therefore unclear risk of bias
  4. Limitation present if (based on CHARMS criteria):
  5. * Data collection not prospective
  6. † Not all eligible neonates recruited resulting in risk of selection bias
  7. ‡ Risk of measurement error in determining outcome status
  8. § Risk of measurement error in determining predictor status
  9. || Sample size less than the recommended
  10. ¶ Missing data causing risk of bias