Table 2 Median (IQR) of heterogeneity metrics for the treatment effect when no effect modification was presenta
From: Quantifying heterogeneity in individual participant data meta-analysis with binary outcomes
Ï„ 2 | Prevalence (%) | Number of studies | \(I^{2}_{\mathrm {two-stage}}\) | \(R^{2}_{\mathrm {two-stage}}\) | \(I^{2}_{\mathrm {one-stage}}\) | \(R^{2}_{\mathrm {two-stage}}\) |
|---|---|---|---|---|---|---|
0.5 | 30 | 15 | 0.10 (0.33) | 1.22 (0.80) | 0.58 (0.41) | 1.75 (1.13) |
1.0 | 30 | 15 | 0.44 (0.36) | 2.30 (1.76) | 0.83 (0.15) | 3.29 (2.41) |
1.5 | 30 | 15 | 0.58 (0.30) | 3.22 (2.53) | 0.89 (0.09) | 5.84 (4.24) |
0.5 | 70 | 15 | 0.01 (0.26) | 1.00 (0.65) | 0.52 (0.47) | 1.76 (1.11) |
1.0 | 70 | 15 | 0.39 (0.42) | 2.12 (1.69) | 0.80 (0.18) | 3.33 (2.26) |
1.5 | 70 | 15 | 0.55 (0.32) | 3.07 (2.67) | 0.87 (0.11) | 5.66 (4.36) |
0.5 | 30 | 30 | 0.12 (0.28) | 1.29 (0.72) | 0.60 (0.32) | 1.79 (0.84) |
1.0 | 30 | 30 | 0.47 (0.25) | 2.44 (1.29) | 0.84 (0.09) | 3.49 (1.61) |
1.5 | 30 | 30 | 0.62 (0.19) | 3.54 (1.98) | 0.90 (0.05) | 6.32 (3.26) |
0.5 | 70 | 30 | 0.06 (0.22) | 1.14 (0.57) | 0.56 (0.34) | 1.81 (0.82) |
1.0 | 70 | 30 | 0.42 (0.28) | 2.30 (1.30) | 0.82 (0.11) | 3.52 (1.80) |
1.5 | 70 | 30 | 0.59 (0.20) | 3.37 (1.93) | 0.88 (0.07) | 6.36 (3.14) |