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Table 3 A priori defined data collection elements

From: Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol

Data collection element Items
Study Characteristics Author
Year of publication
Funding support
Country
Study design
Total number of animals used
N per independent intervention group
Species
Strain
Gender
Weight
Mean age
MI model (i.e. LAD ligation, ischemia reperfusion, cryoinjury, microembolism)
Intercurrent illness of animal
Anesthetic administered
Intervention Characteristics Route of MSC delivery (intravenous, intracoronary, intramyocardial)
Timing of MSC delivery
Frequency of MSC delivery
Source of MSCs (syngenic, allogeneic, xenogenic)
Tissue origin of MSCs (bone marrow, adipose, Wharton’s jelly)
Condition of MSCs (fresh, cryopreserved)
Vehicle
Defining criteria for MSCs