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Table 1 Preclinical models of perioperative myocardial infarctiona

From: Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol

Class Example
Ligation of the left coronary artery Open chest, closed chest
Ischemia-reperfusion Global ischemia-reperfusion model
Cryoinjury Liquid nitrogen cooled copper probe used to injure coronary vessel
Microembolism Injection of automicrothrombotic particulates into coronaries
Electrocauterisation Direct electorcauterization of a coronary vessel
Pharmacological induction Isoproterenol
Genetic model Watanabe heritable hyperlipidemic rabbits with acute induced infarction
  1. aAll included models must provide an anesthetic either pre-induction or concurrent with the induction of myocardial infarction