Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol

Table 1 Preclinical models of perioperative myocardial infarction^a

Class	Example
Ligation of the left coronary artery	Open chest, closed chest
Ischemia-reperfusion	Global ischemia-reperfusion model
Cryoinjury	Liquid nitrogen cooled copper probe used to injure coronary vessel
Microembolism	Injection of automicrothrombotic particulates into coronaries
Electrocauterisation	Direct electorcauterization of a coronary vessel
Pharmacological induction	Isoproterenol
Genetic model	Watanabe heritable hyperlipidemic rabbits with acute induced infarction

^aAll included models must provide an anesthetic either pre-induction or concurrent with the induction of myocardial infarction

ISSN: 2046-4053