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Table 2 Risk and quality assessment of eligible studies

From: Interventions for acute stroke management in Africa: a systematic review of the evidence

  Appraisal questions for cohort studies Bryer and Wasserman 2012 Villiers et al. 2009 Klemperer et al. 2014
1 Were the groups similar and recruited from the same population? Yes Yes Yes
2 Were the exposures measured similarly to assign people to both exposed and unexposed groups? Yes Yes Yes
3 Was the exposure measured in a valid and reliable way? Yes Yes Yes
4 Were confounding factors identified? Yes Yes Yes
5 Were strategies to deal with confounding factors stated? No No Yes
6 Were the groups/participants free of the outcome at the start of the study (or at the moment of exposure)? Yes Yes Yes
7 Were the outcomes measured in a valid and reliable way? Yes Yes Yes
8 Was the follow up time reported and sufficient to belong enough for outcomes to occur? Yes No Yes
9 Was follow-up complete, and if not, were the reasons to loss to follow-up described and explored? NA NA NA
10 Were strategies to address incomplete follow-up utilised? NA NA NA
11 Was appropriate statistical analysis used? Yes Yes Yes
  Critical appraisal questions for case series study Naima Chtaou et al. 2016   
1 Were there clear criteria for inclusion in the case series? Yes
2 Was the condition measured in a standard, reliable way for all participants included in the case series? Yes
3 Were valid methods used for identification of the condition for all participants included in the case series? Yes
4 Did the case series have consecutive inclusion of participants? Yes
5 Did the case series have complete inclusion of participants? Yes
6 Was there clear reporting of the demographics of the participants in the study? Yes
7 Was there clear reporting of clinical information of the participants? Yes
8 Were the outcomes or follow up results of cases clearly reported? Yes
9 Was there clear reporting of the presenting site(s)/clinic(s) demographic information? No
10 Was statistical analysis appropriate? Yes
11 Were there clear criteria for inclusion in the case series? Yes