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Risk of mortality among children, adolescents, and adults with autism spectrum disorder or attention deficit hyperactivity disorder and their first-degree relatives: a protocol for a systematic review and meta-analysis of observational studies

  • Ferrán Catalá-López1, 2, 3Email authorView ORCID ID profile,
  • Brian Hutton3, 4,
  • Matthew J. Page5,
  • Manuel Ridao6, 7,
  • Jane A. Driver8, 9,
  • Adolfo Alonso-Arroyo10, 11,
  • Jaume Forés-Martos1,
  • Diego Macías Saint-Gerons12, 13,
  • Eduard Vieta14,
  • Alfonso Valencia15, 16 and
  • Rafael Tabarés-Seisdedos1
Systematic Reviews20176:189

Received: 3 April 2017

Accepted: 5 September 2017

Published: 15 September 2017

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Open Peer Review reports

Pre-publication versions of this article are available by contacting

Original Submission
3 Apr 2017 Submitted Original manuscript
3 Jul 2017 Reviewed Reviewer Report - Anna Van Metter
6 Jul 2017 Author responded Author comments - Ferrán Catalá-López
Resubmission - Version 2
6 Jul 2017 Submitted Manuscript version 2
5 Sep 2017 Editorially accepted
15 Sep 2017 Article published 10.1186/s13643-017-0581-9

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting

You can find further information about the peer review system here.

Authors’ Affiliations

Department of Medicine, University of Valencia/INCLIVA Health Research Institute and CIBERSAM, Valencia, Spain
Fundación Instituto de Investigación en Servicios de Salud, Valencia, Spain
Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada
School of Epidemiology, Public Health and Preventative Medicine, University of Ottawa, Ottawa, Canada
School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
Instituto Aragonés de Ciencias de la Salud, Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), Zaragoza, Spain
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Salud Pública), Valencia, Spain
Geriatric Research Education and Clinical Center, VA Boston Healthcare System, Boston, USA
Division of Aging, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA
Department of History of Science and Documentation, University of Valencia, Valencia, Spain
Unidad de Información e Investigación Social y Sanitaria-UISYS, University of Valencia-Spanish National Research Council (CSIC), Valencia, Spain
Division of Pharmacoepidemiology and Pharmacovigilance, Spanish Medicines and Healthcare Products Agency, Madrid, Spain
Department of Health Systems and Services, Pan American Health Organization, Unit of Medicines and Health Technologies, Washington, USA
Hospital Clínic, Universitat de Barcelona, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and CIBERSAM, Barcelona, Spain
Life Sciences Department, Barcelona Supercomputing Center, Barcelona, Spain
Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain